ChemicalBook > CAS DataBase List > 2-(3-Chloro-phenyl)-pyrrolidine

2-(3-Chloro-phenyl)-pyrrolidine

Product Name
2-(3-Chloro-phenyl)-pyrrolidine
CAS No.
298690-74-1
Chemical Name
2-(3-Chloro-phenyl)-pyrrolidine
Synonyms
AKOS BB-8867;CHEMBRDG-BB 4006410;2-(3-CHLOROPHENYL)PYRROLIDINE;Pyrrolidine, 2-(3-chlorophenyl)-;(+/-)-2-(3-chlorophenyl)-pyrrolidine
CBNumber
CB4175836
Molecular Formula
C10H12ClN
Formula Weight
181.66
MOL File
298690-74-1.mol
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2-(3-Chloro-phenyl)-pyrrolidine Property

Boiling point:
138-141 °C(Press: 16 Torr)
Density 
1.129±0.06 g/cm3(Predicted)
storage temp. 
2-8°C(protect from light)
pka
9.58±0.10(Predicted)
CAS DataBase Reference
298690-74-1(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36
Safety Statements 
26
HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H314Causes severe skin burns and eye damage

H361Suspected of damaging fertility or the unborn child

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P308+P313IF exposed or concerned: Get medical advice/attention.

P363Wash contaminated clothing before reuse.

P391Collect spillage. Hazardous to the aquatic environment

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
C350775
Product name
2-(3-Chlorophenyl)pyrrolidine
Packaging
100mg
Price
$45
Updated
2021/12/16
Apolloscientific
Product number
OR962418
Product name
2-(3-Chlorophenyl)pyrrolidine
Purity
97%
Packaging
5g
Price
$345
Updated
2021/12/16
Apolloscientific
Product number
OR962418
Product name
2-(3-Chlorophenyl)pyrrolidine
Purity
97%
Packaging
1g
Price
$115
Updated
2021/12/16
AK Scientific
Product number
3067AB
Product name
2-(3-Chlorophenyl)pyrrolidine
Packaging
1g
Price
$246
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC50791
Product name
2-(3-Chlorophenyl)pyrrolidine
Packaging
1g
Price
$260.6
Updated
2021/12/16
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2-(3-Chloro-phenyl)-pyrrolidine Chemical Properties,Usage,Production

Uses

Used as an intermediate for organic synthesis.

Application

(+/-)-2-(3-chlorophenyl)-pyrrolidine has a wide application in synthesis of pharma intermediates,It is also used as an antioxidant.

Reactions

2-(3-Chloro-phenyl)-pyrrolidine is an important building block for the synthesis of various organic compounds. Through the coupling of the amine, It could be employed to couple with 4-(4-formylphenoxy)-1-naphthamide to synthesize 4-[4-[2-(3-Chlorophenyl)pyrrolidin-1-yl]methylphenoxyl]-1-naphthamide which is an aminobenzyloxyarylamide derivatives and act as κ opioid receptor antagonists.

Synthesis

To a solution of substituted benzoic acid inabsolute ethyl alcohol was slowly added thionyl chloride. The mixture was heated to reflux for 2h, and then cooledto room temperature. The solvent was removed and the solid residuewas dissolved in ethyl acetate, and washed withsaturated NaHCO3 solution. After a series of reactions, 3-(2-chloro-phenyl)-pyrrolidine can be obtained.

2-(3-Chloro-phenyl)-pyrrolidine Preparation Products And Raw materials

Raw materials

Preparation Products

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2-(3-Chloro-phenyl)-pyrrolidine Suppliers

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View Lastest Price from 2-(3-Chloro-phenyl)-pyrrolidine manufacturers

Career Henan Chemical Co
Product
3-(2-CHLORO-PHENYL)-PYRROLIDINE 298690-74-1
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100KG
Release date
2019-12-23