H-SER-CYS-SER-LEU-PRO-GLN-THR-SER-GLY-LEU-GLN-LYS-PRO-GLU-SER-NH2

ChemicalBook > CAS DataBase List > H-SER-CYS-SER-LEU-PRO-GLN-THR-SER-GLY-LEU-GLN-LYS-PRO-GLU-SER-NH2

H-SER-CYS-SER-LEU-PRO-GLN-THR-SER-GLY-LEU-GLN-LYS-PRO-GLU-SER-NH2

Product Name: H-SER-CYS-SER-LEU-PRO-GLN-THR-SER-GLY-LEU-GLN-LYS-PRO-GLU-SER-NH2
CAS No.: 258276-95-8
Chemical Name: H-SER-CYS-SER-LEU-PRO-GLN-THR-SER-GLY-LEU-GLN-LYS-PRO-GLU-SER-NH2
Synonyms: SCSLPQTSGLQKPES;LEP (116-130) (mouse);LEPTIN (116-130) MOUSE;Mouse leptin(116-130) amide;LEPTIN (116-130) AMIDE (MOUSE);obese gene peptide 116-130 amide;LEPTIN FRAGMENT 116-130 AMIDE, MOUSE;OBESE GENE PEPTIDE (116-130) AMIDE (MOUSE);Leptin fragment 116-130 amide mouse, >95%(HPLC);SER-CYS-SER-LEU-PRO-GLN-THR-SER-GLY-LEU-GLN-LYS-PRO-GLU-SER
CBNumber: CB4178660
Molecular Formula: C64H109N19O24S
Formula Weight: 1560.73
MOL File: 258276-95-8.mol

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H-SER-CYS-SER-LEU-PRO-GLN-THR-SER-GLY-LEU-GLN-LYS-PRO-GLU-SER-NH2 Property

Boiling point:: 2035.4±65.0 °C(Predicted)
Density: 1.372±0.06 g/cm3(Predicted)
storage temp.: −20°C
solubility: insoluble in EtOH; ≥156 mg/mL in DMSO; ≥24.15 mg/mL in H2O
form: white powder
pka: 4.44±0.10(Predicted)
color: White to off-white
Sequence: H-Ser-Cys-Ser-Leu-Pro-Gln-Thr-Ser-Gly-Leu-Gln-Lys-Pro-Glu-Ser-OH

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris

Product number: 2985
Product name: LEP(116-130)(mouse)
Packaging: 1
Price: $235
Updated: 2021/12/16

ApexBio Technology

Product number: A1024
Product name: LEP(116-130)(mouse)
Packaging: 5mg
Price: $240
Updated: 2021/12/16

ApexBio Technology

Product number: A1024
Product name: LEP(116-130)(mouse)
Packaging: 10mg
Price: $400
Updated: 2021/12/16

ApexBio Technology

Product number: A1024
Product name: LEP(116-130)(mouse)
Packaging: 25mg
Price: $560
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: PEP0002368
Product name: LEPTIN (116-130), MOUSE
Purity: 95.00%
Packaging: 0.5MG
Price: $643.91
Updated: 2021/12/16

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H-SER-CYS-SER-LEU-PRO-GLN-THR-SER-GLY-LEU-GLN-LYS-PRO-GLU-SER-NH2 Chemical Properties,Usage,Production

Biological Activity

leptin (116-130), amide, mouse(c64h109n19o24s),a peptide with the sequence ser-cys-ser-leu-pro-gln-thr-ser-gly-leu-gln-lys-pro-glu-ser-nh2. leptin is an adipocyte-derived hormone that acts as a major regulator for food intake and energy homeostasis. leptin deficiency or resistance can result in profound obesity, diabetes, and infertility in humans. since the discovery of leptin, the breadth of biological actions has dramatically expanded and served to broaden the initial perspective, where this protein was viewed solely as an antiobesity hormone. important biological activities have been discovered in peripheral tissues that demonstrate the pleiotropic effects of this molecule in such areas as hematopoiesis, angiogenesis, blood pressure, bone mass, lymphoid organ homeostasis, and t lymphocyte function. recent data indicate that leptin(116-130), an active fragment of the native molecule, exerts effects similar to those of the native peptide on body weight and food intake.figure1 formula of leptin (116-130)figure2 signal transduction pathways of leptin

References

1. Zhang F, Basinski MB, Beals JM, Briggs SL, Churgay LM, Clawson DK, DiMarchi RD, Furman TC, Hale JE, Hsiung HM, Schoner BE, Smith DP, Zhang XY, Wery JP, Schevitz RW (May 1997). "Crystalstructure of the obese protein leptin-E100". Nature 387 (6629): 206–9.2. Brennan AM, Mantzoros CS (June 2006). "Drug Insight: the role of leptin in human physiology and pathophysiology--emerging clinical applications". Nat Clin Pract Endocrinol Metab 2 (6): 318–327. 3. GreGreen ED, Maffei M, Braden VV, Proenca R, DeSilva U, Zhang Y, Chua SC Jr, Leibel RL, Weissenbach J, Friedman JM (August 1995). "The human obese (OB) gene: RNA expression pattern and mapping on the physical, cytogenetic, and genetic maps of chromosome 7". Genome Res. 5 (1): 5–12.4. Margetic S, Gazzola C, Pegg GG, Hill RA (2002). "Leptin: a review of its peripheral actions and interactions". Int. J. Obes. Relat. Metab. Disord. 26 (11): 1407–1433.

H-SER-CYS-SER-LEU-PRO-GLN-THR-SER-GLY-LEU-GLN-LYS-PRO-GLU-SER-NH2 Preparation Products And Raw materials

Raw materials

Preparation Products

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H-SER-CYS-SER-LEU-PRO-GLN-THR-SER-GLY-LEU-GLN-LYS-PRO-GLU-SER-NH2 Suppliers

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View Lastest Price from H-SER-CYS-SER-LEU-PRO-GLN-THR-SER-GLY-LEU-GLN-LYS-PRO-GLU-SER-NH2 manufacturers

Career Henan Chemical Co

Product: H-SER-CYS-SER-LEU-PRO-GLN-THR-SER-GLY-LEU-GLN-LYS-PRO-GLU-SER-NH2 258276-95-8
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100KG
Release date: 2020-02-16

258276-95-8, H-SER-CYS-SER-LEU-PRO-GLN-THR-SER-GLY-LEU-GLN-LYS-PRO-GLU-SER-NH2Related Search:

LEPTIN (150-167) (HUMAN) LEPTIN (138-167) (HUMAN) LEPTIN (22-56), HUMAN LEPTIN (93-105) (HUMAN) TYR-LEPTIN (26-39) (HUMAN) H-SER-CYS-SER-LEU-PRO-GLN-THR-SER-GLY-LEU-GLN-LYS-PRO-GLU-SER-NH2

SCSLPQTSGLQKPES

SER-CYS-SER-LEU-PRO-GLN-THR-SER-GLY-LEU-GLN-LYS-PRO-GLU-SER

SER-CYS-SER-LEU-PRO-GLN-THR-SER-GLY-LEU-GLN-LYS-PRO-GLU-SER-NH2

OBESE GENE PEPTIDE (116-130) AMIDE (MOUSE)

Leptin fragment 116-130 amide mouse, >95%(HPLC)

obese gene peptide 116-130 amide

H-Ser-Cys-Ser-Leu-Pro-Gln-Thr-Ser-Gly-Leu-Gln-Lys-Pro-Glu-Ser-OH

SER-CYS-SER-LEU-PRO-GLN-THR-SER-GLY-LEU-GLN-LYS-PRO-GLU-SER-NH2: SCSLPQTSGLQKPES-NH2

SER-CYS-SER-LEU-PRO-GLN-THR-SER-GLY-LEU-GLN-LYS-PRO-GLU-SER: SCSLPQTSGLQKPES

LEP (116-130) (mouse)

Leptin (116-130) aMide (Mouse) Obese Gene Peptide (116-130) aMide (Mouse)

H-SER-CYS-SER-LEU-PRO-GLN-THR-SER-GLY-LEU-GLN-LYS-PRO-GLU-SER-NH2

LEPTIN FRAGMENT 116-130 AMIDE, MOUSE

LEPTIN (116-130) AMIDE (MOUSE)

LEPTIN (116-130) MOUSE

L-Serinamide,L-seryl-L-cysteinyl-L-seryl-L-leucyl-L-prolyl-L-glutaminyl-L-threonyl-L-serylglycyl-L-leucyl-L-glutaminyl-L-lysyl-L-prolyl-L-a-glutamyl-

L-Seryl-L-cysteinyl-L-seryl-L-leucyl-L-prolyl-L-glutaminyl-L-threonyl-L-serylglycyl-L-leucyl-L-glutaminyl-L-lysyl-L-prolyl-L-alpha-glutamyl-L-serinamide

Mouse leptin(116-130) amide

L-Serinamide, L-seryl-L-cysteinyl-L-seryl-L-leucyl-L-prolyl-L-glutaminyl-L-threonyl-L-serylglycyl-L-leucyl-L-glutaminyl-L-lysyl-L-prolyl-L-α-glutamyl-

LEP(116-130)(mouse),Inhibitor,LEP(116130)(mouse),inhibit,LEP(116 130)(mouse)

258276-95-8

C64H107N18O25S

C64H109N19O24S

BioChemical

Cell Biology

Cell Signaling and Neuroscience

Leptin (OB)

Hormones

Obesity Research

Cytokines, Growth Factors and Hormones

Peptide

Immunology