1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE-N-(CARBOXYFLUORESCEIN)

1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE-N-(CARBOXYFLUORESCEIN) Property

storage temp. 

−20°C

form 

solution

Safety

Safety Statements 

22-24/25

WGK Germany 

3

Storage Class

6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects

Hazard Classifications

Acute Tox. 3 Inhalation
Acute Tox. 4 Oral
Carc. 2
Eye Irrit. 2
Repr. 2
Skin Irrit. 2
STOT RE 1 Oral
STOT SE 3

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H331Toxic if inhaled

H336May cause drowsiness or dizziness

H351Suspected of causing cancer

H372Causes damage to organs through prolonged or repeated exposure

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE-N-(CARBOXYFLUORESCEIN) Chemical Properties,Usage,Production

Uses

18:1 PE CF may be used:

• to spike human serum
• to prepare concentrated lipid mix, PC:PE:fluoPE to assess basal binding properties and PC:PE:fluoPE:PIP to assess specific binding properties of the protein to each phosphoinositides (PIP)
• to prepare the large unilamellar vesicles (LUVs)
• in the preparation of fluorescent phosphoinositide?containing liposomes
• for fluorescent labeling of total lipids to the initial liposome formulation mixture
• in the formulation of pegylated magneto-liposomes (MLs) and transferrin (Tf) embedding

Biological Activity

Phosphatidylethanolamine controls the membrane fluidity in eukaryotic cells. Phosphoethanolamine (PHOS) has the ability to repress tumour growth both in vitro and in vivo. It possesses anticarcinogenic effects. It can also prevent the mRNA expression of cyclin D1 and VEGFR1 (vascular endothelial growth factor receptor 1).