Definition Pharmaceutical Properties
ChemicalBook > CAS DataBase List > CALYCOSIN

CALYCOSIN

Definition Pharmaceutical Properties
Product Name
CALYCOSIN
CAS No.
20575-57-9
Chemical Name
CALYCOSIN
Synonyms
Clycosin;CALYCOSIN;Calycosin-RM;CALYCOSIN(SH);Astraisoflavone;Calycosin 20575-57-9;Calycosin (Cyclosin);3'-HYDROXYFORMONONETIN;Calycosin >=98% (HPLC);Balofloxacin Impurity 8
CBNumber
CB4182878
Molecular Formula
C16H12O5
Formula Weight
284.26
MOL File
20575-57-9.mol
More
Less

CALYCOSIN Property

Melting point:
245~247℃
Boiling point:
536.8±50.0 °C(Predicted)
Density 
1.420±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,2-8°C
solubility 
methanol: soluble1mg/mL, clear, colorless
pka
6.94±0.20(Predicted)
form 
powder
color 
white to light yellow
InChI
InChI=1S/C16H12O5/c1-20-14-5-2-9(6-13(14)18)12-8-21-15-7-10(17)3-4-11(15)16(12)19/h2-8,17-18H,1H3
InChIKey
ZZAJQOPSWWVMBI-UHFFFAOYSA-N
SMILES
C1OC2=CC(O)=CC=C2C(=O)C=1C1=CC=C(OC)C(O)=C1
More
Less

Safety

Hazard Codes 
T
Risk Statements 
25
Safety Statements 
45
RIDADR 
UN 3462 6.1 / PGIII
WGK Germany 
3
HS Code 
2932996560
Hazardous Substances Data
20575-57-9(Hazardous Substances Data)
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

Precautionary statements

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHL82491
Product name
Calycosin
Purity
phyproof? Reference Substance
Packaging
10mg
Price
$629
Updated
2024/03/01
Sigma-Aldrich
Product number
1087472
Product name
Calycosin
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
50mg
Price
$303
Updated
2024/03/01
Cayman Chemical
Product number
25091
Product name
Calycosin
Purity
≥98%
Packaging
5mg
Price
$81
Updated
2024/03/01
Cayman Chemical
Product number
25091
Product name
Calycosin
Purity
≥98%
Packaging
10mg
Price
$152
Updated
2024/03/01
Sigma-Aldrich
Product number
B9938
Product name
Calycosin
Purity
≥98% (HPLC)
Packaging
10mg
Price
$350
Updated
2024/03/01
More
Less

CALYCOSIN Chemical Properties,Usage,Production

Definition

Calycosin is an O-methylated isoflavone. It can be isolated from Astragalus membranaceus Bge. var. mongholicus and Trifolium pratense L. Calycosin is a member of the class of 7-hydroxyisoflavones that is 7-hydroxyisoflavone which is substituted by an additional hydroxy group at the 3' position and a methoxy group at the 4' position. It has a role as a metabolite and an antioxidant. It is a member of 7-hydroxyisoflavones and a member of 4'-methoxyisoflavones. It derives from an isoflavone. It is a conjugate acid of a calycosin(1-).

Pharmaceutical Properties

The potential pharmaceutical properties of calycosin in the treatment of tumors, inflammation, stroke, and cardiovascular diseases have gained increasing attention in the recent years. The literature survey showed that calycosin exhibits promising effects for the treatment of several diseases and that these effects may be due to its isoflavonoid and phytoestrogenic properties. The effects of calycosin most likely result from its interaction with the ER receptors on the cell membrane and the modulation of the MAPK signaling pathway.
Through its effect on this pathway, calycosin can regulate several cell activities, such as apoptosis and angiogenesis, which enables its therapeutic functions. 

Uses

Calycosin is a known antioxidant that prevent redox imbalance in organisms. Also, it possesses anti-tumor, anti-inflammation and osteogenic properties; Useful as a therapeutic reagent for bone loss-associated diseases.

Definition

ChEBI: Calycosin is a member of the class of 7-hydroxyisoflavones that is 7-hydroxyisoflavone which is substituted by an additional hydroxy group at the 3' position and a methoxy group at the 4' position. It has a role as a metabolite and an antioxidant. It is a member of 7-hydroxyisoflavones and a member of 4'-methoxyisoflavones. It is functionally related to an isoflavone. It is a conjugate acid of a calycosin(1-).

CALYCOSIN Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

CALYCOSIN Suppliers

Shanghai Standard Technology Co.,Ltd.
Tel
021-021-57127007-6622-6622 17621252073
Fax
+86 (21) 5132-0077
Email
luzh@nature-standard.com
Country
China
ProdList
3021
Advantage
58
Chembest Research Laboratories Limited
Tel
+86-21-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6005
Advantage
61
Beijing HwrkChemical Technology Co., Ltd
Tel
010-89508211 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
8418
Advantage
55
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14103
Advantage
59
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18738
Advantage
57
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11707
Advantage
57
Shenzhen Sungening Bio-Tech Co., Ltd
Tel
+86-0755-89668383
Fax
+86-0755-89594066/4038
Email
sales@sungening.com
Country
China
ProdList
1319
Advantage
65
Dalian Meilun Biotech Co., Ltd.
Tel
0411-62910999 13889544652
Email
meilunui@163.com
Country
China
ProdList
4727
Advantage
58
BioBioPha Co., Ltd.
Tel
0871-65217109 13211707573;
Fax
0871-65215563
Email
y.liu@mail.biobiopha.com
Country
China
ProdList
5653
Advantage
65
ShangHai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847 13636370518
Fax
021-55068248
Email
shyysw007@163.com
Country
China
ProdList
4940
Advantage
60
More
Less

View Lastest Price from CALYCOSIN manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Calycosin 20575-57-9
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-06-07
Hebei Dangtong Import and export Co LTD
Product
CALYCOSIN 20575-57-9
Price
US $510.00-470.00/Grams
Min. Order
10Grams
Purity
99.99%
Supply Ability
100Tons
Release date
2023-03-21
Hebei Weibang Biotechnology Co., Ltd
Product
CALYCOSIN 20575-57-9
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 mt
Release date
2024-11-07

20575-57-9, CALYCOSINRelated Search:


  • CALYCOSIN
  • 7,3'-DIHYDROXY-4'-METHOXYISOFLAVONE
  • 3'-HYDROXYFORMONONETIN
  • 3',7-DIHYDROXY-4'-METHOXYISOFLAVONE
  • 3-(3-Hydroxy-4-methoxyphenyl)-7-hydroxy-4H-1-benzopyran-4-one
  • 7-Hydroxy-3-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one
  • Astraisoflavone
  • Clycosin
  • CALYCOSIN(SH)
  • Calycosin 20575-57-9
  • 7-hydroxy-3-(3-hydroxy-4-methoxyphenyl)-1-benzopyran-4-one
  • Calycosin, 98%, from Astragalus membranaceus Bunge
  • 7-hydroxy-3-(3-hydroxy-4-methoxyphenyl)-4H-chromen-4-one
  • Calycosin (Cyclosin)
  • 4H-1-Benzopyran-4-one, 7-hydroxy-3-(3-hydroxy-4-methoxyphenyl)-
  • Calycosin >=98% (HPLC)
  • 3',7-Dihydroxy-4'-methoxy-isoflavone7-hydroxy-3-(3-hydroxy-4-methoxyphenyl)chromen-4-one
  • 7,3'-dihydroxy-4'-methoxyisoflavanon-2-ene
  • 7,5'-dihydroxy-4'-methoxyisoflavone
  • 7-hydroxy-3-(3-hydroxy-4-methoxyphenyl)-
  • 7-Hydroxy-3-(3-hydroxy-4-methoxyphenyl)-4H-chromen-4-one4H-1-Benzopyran-4-one
  • 7-Hydroxy-3-(3-hydroxy-4-methoxyphenyl)-4H-chromen-4-one[Cyclosin]
  • Calycosin-RM
  • Balofloxacin Impurity 8
  • 20575-57-9
  • C16H12O5
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
  • reference substance
  • Iso-Flavones
  • The group of Astralosides