2-THIENYL-2-DIMETHYLAMINOETHYL KETONE HCL

Product Name: 2-THIENYL-2-DIMETHYLAMINOETHYL KETONE HCL
CAS No.: 5424-47-5
Chemical Name: 2-THIENYL-2-DIMETHYLAMINOETHYL KETONE HCL
Synonyms: Duloxetine-16;Compound Fr12480;SALOR-INT L158135-1EA;Duloxetine Impurity 18;Duloxetine Impurity 9 HCl;2-THIENYL-2-DIMETHYLAMINOETHYL KETONE HCL;3-DIMETHYLAMINO-1-(2-THIENYL)-1-PROPANONE HCl;3-(dimethylamino)-1-(thiophen-2-yl)propan-1-one;2-Thienyl-2-dimethylaminoethyl ketone hydrochloride;3-(dimethylamino)-1-(thiophen-2-yl)propan-1-one HCl
CBNumber: CB4188269
Molecular Formula: C9H14ClNOS
Formula Weight: 219.73
MOL File: 5424-47-5.mol

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2-THIENYL-2-DIMETHYLAMINOETHYL KETONE HCL Property

Melting point:: 176.0 to 182.0 °C
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
solubility: soluble in Methanol
form: powder to crystal
color: White to Almost white
InChI: InChI=1S/C9H13NOS.ClH/c1-10(2)6-5-8(11)9-4-3-7-12-9;/h3-4,7H,5-6H2,1-2H3;1H
InChIKey: HPVHJPMLORARSR-UHFFFAOYSA-N
SMILES: C1(SC=CC=1)C(=O)CCN(C)C.Cl

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Safety

HS Code: 2934.99.4400

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: L158135
Product name: 3-(DIMETHYLAMINO)-1-(2-THIENYL)-1-PROPANONE HYDROCHLORIDE
Purity: Aldrich<sup>CPR</sup>
Packaging: 1 unit
Price: $113
Updated: 2025/07/31

Sigma-Aldrich

Product number: L158135
Product name: 3-(DIMETHYLAMINO)-1-(2-THIENYL)-1-PROPANONE HYDROCHLORIDE
Purity: AldrichCPR
Packaging: 50mg
Price: $110
Updated: 2024/03/01

TCI Chemical

Product number: D4011
Product name: 3-(Dimethylamino)-1-(2-thienyl)-1-propanone Hydrochloride
Purity: >98.0%(T)
Packaging: 5g
Price: $295
Updated: 2025/07/31

TRC

Product number: D456770
Product name: 3-(DIMETHYLAMINO)-1-(2-THIENYL)-1-PROPANONE HYDROCHLORIDE
Packaging: 1g
Price: $75
Updated: 2021/12/16

AK Scientific

Product number: J51540
Product name: 3-(Dimethylamino)-1-(thiophen-2-yl)propan-1-onehydrochloride
Packaging: 1g
Price: $90
Updated: 2021/12/16

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2-THIENYL-2-DIMETHYLAMINOETHYL KETONE HCL Chemical Properties,Usage,Production

Uses

3-(Dimethylamino)-1-(2-thienyl)-1-propanone, HCl

Synthesis

88-15-3

50-00-0

506-59-2

5424-47-5

2-Acetylthiophene (128 g, 1.00 mol), dimethylamine hydrochloride (90 g, 1.10 mol), paraformaldehyde (41 g, 1.40 mol), concentrated hydrochloric acid (5 mL), and isopropanol (500 mL) were mixed and heated and refluxed for 6 hours according to the method reported by Robertson [1]. Upon completion of the reaction, the reaction solution was cooled to 0 °C and stirring was continued for 1 hour. Subsequently, the reaction mixture was filtered, the solid product was washed with cold isopropanol and finally dried at 50 °C for 16 h to give 3-dimethylamino-1-(thiophen-2-yl)-propan-1-one hydrochloride (2a).

References

[1] Bioorganic Chemistry, 2016, vol. 65, p. 82 - 89
[2] Patent: CN104829587, 2017, B. Location in patent: Paragraph 0050-0052
[3] Tetrahedron Letters, 1990, vol. 31, # 45, p. 7101 - 7104
[4] Patent: EP2305669, 2011, A1. Location in patent: Page/Page column 1.1
[5] Organic Process Research and Development, 2006, vol. 10, # 5, p. 905 - 913

2-THIENYL-2-DIMETHYLAMINOETHYL KETONE HCL Preparation Products And Raw materials

Raw materials

Preparation Products

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2-THIENYL-2-DIMETHYLAMINOETHYL KETONE HCL Suppliers

Americas 1 Canada 1 China 153 Europe 1 India 36 Japan 1 United Kingdom 2 United States 18 Global 213

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View Lastest Price from 2-THIENYL-2-DIMETHYLAMINOETHYL KETONE HCL manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 2-Thienyl-2-Dimethylaminoethyl Ketone Hcl 5424-47-5
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98%min
Supply Ability: 30tons/month
Release date: 2023-02-07

Career Henan Chemical Co

Product: 2-THIENYL-2-DIMETHYLAMINOETHYL KETONE HCL 5424-47-5
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: Customized
Release date: 2018-08-20

5424-47-5, 2-THIENYL-2-DIMETHYLAMINOETHYL KETONE HCLRelated Search:

Duloxetine N-DesMethyl Metabolite 1-(2-Thienyl)-1-propanone [4-(4-CHLOROPHENYL)-1-PHENYLTETRAHYDRO-1H-PYRROL-3-YL](2-THIENYL)METHANONE AKOS 91896 AKOS 91759 AKOS 91937 SALOR-INT L436410-1EA AKOS 91761 2-THIENYL-2-DIMETHYLAMINOETHYL KETONE HCL [4-(4-CHLOROPHENYL)-1-METHYLTETRAHYDRO-1H-PYRROL-3-YL](2-THIENYL)METHANONE

SALOR-INT L158135-1EA

2-THIENYL-2-DIMETHYLAMINOETHYL KETONE HCL

3-(DIMETHYLAMINO)-1-(THIOPHEN-2-YL)PROPAN-1-ONE HYDROCHLORIDE

3-DiMethylaMino-1-(2-thienyl)-1-propanone hydrochloride, 97+%

3-DIMETHYLAMINO-1-(2-THIENYL)-1-PROPANONE HCl

2-Thienyl-2-dimethylaminoethyl ketone hydrochloride

2-[3-(Dimethylamino)propionyl]thiophene Hydrochloride

1-Propanone-3-(diMethylaMino)-1-(2-thienyl)- hydrochloride

1-Propanone,3-(diMethylaMino)-1-(2-thienyl)-, hydrochloride (1:1)

3-(dimethylamino)-1-(thiophen-2-yl)propan-1-one

1,5-Bis(dimethylamino)-1,5-di(thiophen-2-yl)pentan-3-one hydrochloride

Duloxetine Impurity 18

Duloxetine-16

3-(Dimethylamino)-1-(2-thienyl)-1-propanoneHydrochloride&gt

3-(N,N-dimethylamino)-1-(thiophen-2-yl)-propan-1-one hydrochloride

Duloxetine Impurity 9 HCl

3-Dimethyl amino-1-(2-thienyl)-1-propanone hydrochlorideQ: What is 3-Dimethyl amino-1-(2-thienyl)-1-propanone hydrochloride Q: What is the CAS Number of 3-Dimethyl amino-1-(2-thienyl)-1-propanone hydrochloride Q: What is the storage condition of 3-Dimethyl amino-1-(2-thienyl)-1-propanone hydrochloride

3-(dimethylamino)-1-(2-thienyl)-1-Propanone hydrochloride (1:1)

Compound Fr12480

3-(Dimethylamino)-1-(thiophen-2-yl)propan-1-onehydrochloride(DuloxetineImpurity)

3-(dimethylamino)-1-(thiophen-2-yl)propan-1-one HCl

3-(Dimethylamino)-1-(2-thienyl)propanone hydrochloride

3-(Dimethylamino)-1-(thiophen-2-yl)-1-propanone HCl

5424-47-5

C9H14ClNOS

C9H13NOSHCl

C17H25ClN2OS2