ChemicalBook > CAS DataBase List > 2-THIENYL-2-DIMETHYLAMINOETHYL KETONE HCL

2-THIENYL-2-DIMETHYLAMINOETHYL KETONE HCL

Product Name
2-THIENYL-2-DIMETHYLAMINOETHYL KETONE HCL
CAS No.
5424-47-5
Chemical Name
2-THIENYL-2-DIMETHYLAMINOETHYL KETONE HCL
Synonyms
Duloxetine-16;Compound Fr12480;SALOR-INT L158135-1EA;Duloxetine Impurity 18;Duloxetine Impurity 9 HCl;2-THIENYL-2-DIMETHYLAMINOETHYL KETONE HCL;3-DIMETHYLAMINO-1-(2-THIENYL)-1-PROPANONE HCl;3-(dimethylamino)-1-(thiophen-2-yl)propan-1-one;2-Thienyl-2-dimethylaminoethyl ketone hydrochloride;3-(dimethylamino)-1-(thiophen-2-yl)propan-1-one HCl
CBNumber
CB4188269
Molecular Formula
C9H14ClNOS
Formula Weight
219.73
MOL File
5424-47-5.mol
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2-THIENYL-2-DIMETHYLAMINOETHYL KETONE HCL Property

Melting point:
176.0 to 182.0 °C
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
soluble in Methanol
form 
powder to crystal
color 
White to Almost white
InChI
InChI=1S/C9H13NOS.ClH/c1-10(2)6-5-8(11)9-4-3-7-12-9;/h3-4,7H,5-6H2,1-2H3;1H
InChIKey
HPVHJPMLORARSR-UHFFFAOYSA-N
SMILES
C1(SC=CC=1)C(=O)CCN(C)C.Cl
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Safety

HS Code 
2934.99.4400
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
L158135
Product name
3-(DIMETHYLAMINO)-1-(2-THIENYL)-1-PROPANONE HYDROCHLORIDE
Purity
Aldrich<sup>CPR</sup>
Packaging
1 unit
Price
$113
Updated
2025/07/31
Sigma-Aldrich
Product number
L158135
Product name
3-(DIMETHYLAMINO)-1-(2-THIENYL)-1-PROPANONE HYDROCHLORIDE
Purity
AldrichCPR
Packaging
50mg
Price
$110
Updated
2024/03/01
TCI Chemical
Product number
D4011
Product name
3-(Dimethylamino)-1-(2-thienyl)-1-propanone Hydrochloride
Purity
>98.0%(T)
Packaging
5g
Price
$295
Updated
2025/07/31
TRC
Product number
D456770
Product name
3-(DIMETHYLAMINO)-1-(2-THIENYL)-1-PROPANONE HYDROCHLORIDE
Packaging
1g
Price
$75
Updated
2021/12/16
AK Scientific
Product number
J51540
Product name
3-(Dimethylamino)-1-(thiophen-2-yl)propan-1-onehydrochloride
Packaging
1g
Price
$90
Updated
2021/12/16
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2-THIENYL-2-DIMETHYLAMINOETHYL KETONE HCL Chemical Properties,Usage,Production

Uses

3-(Dimethylamino)-1-(2-thienyl)-1-propanone, HCl

Synthesis

88-15-3

50-00-0

506-59-2

5424-47-5

2-Acetylthiophene (128 g, 1.00 mol), dimethylamine hydrochloride (90 g, 1.10 mol), paraformaldehyde (41 g, 1.40 mol), concentrated hydrochloric acid (5 mL), and isopropanol (500 mL) were mixed and heated and refluxed for 6 hours according to the method reported by Robertson [1]. Upon completion of the reaction, the reaction solution was cooled to 0 °C and stirring was continued for 1 hour. Subsequently, the reaction mixture was filtered, the solid product was washed with cold isopropanol and finally dried at 50 °C for 16 h to give 3-dimethylamino-1-(thiophen-2-yl)-propan-1-one hydrochloride (2a).

References

[1] Bioorganic Chemistry, 2016, vol. 65, p. 82 - 89
[2] Patent: CN104829587, 2017, B. Location in patent: Paragraph 0050-0052
[3] Tetrahedron Letters, 1990, vol. 31, # 45, p. 7101 - 7104
[4] Patent: EP2305669, 2011, A1. Location in patent: Page/Page column 1.1
[5] Organic Process Research and Development, 2006, vol. 10, # 5, p. 905 - 913

2-THIENYL-2-DIMETHYLAMINOETHYL KETONE HCL Preparation Products And Raw materials

Raw materials

Preparation Products

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2-THIENYL-2-DIMETHYLAMINOETHYL KETONE HCL Suppliers

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View Lastest Price from 2-THIENYL-2-DIMETHYLAMINOETHYL KETONE HCL manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
2-Thienyl-2-Dimethylaminoethyl Ketone Hcl 5424-47-5
Price
US $0.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
30tons/month
Release date
2023-02-07
Career Henan Chemical Co
Product
2-THIENYL-2-DIMETHYLAMINOETHYL KETONE HCL 5424-47-5
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
Customized
Release date
2018-08-20

5424-47-5, 2-THIENYL-2-DIMETHYLAMINOETHYL KETONE HCLRelated Search:

Duloxetine N-DesMethyl Metabolite 1-(2-Thienyl)-1-propanone [4-(4-CHLOROPHENYL)-1-PHENYLTETRAHYDRO-1H-PYRROL-3-YL](2-THIENYL)METHANONE AKOS 91896 AKOS 91759 AKOS 91937 SALOR-INT L436410-1EA AKOS 91761 2-THIENYL-2-DIMETHYLAMINOETHYL KETONE HCL [4-(4-CHLOROPHENYL)-1-METHYLTETRAHYDRO-1H-PYRROL-3-YL](2-THIENYL)METHANONE

  • SALOR-INT L158135-1EA
  • 2-THIENYL-2-DIMETHYLAMINOETHYL KETONE HCL
  • 3-(DIMETHYLAMINO)-1-(THIOPHEN-2-YL)PROPAN-1-ONE HYDROCHLORIDE
  • 3-DiMethylaMino-1-(2-thienyl)-1-propanone hydrochloride, 97+%
  • 3-DIMETHYLAMINO-1-(2-THIENYL)-1-PROPANONE HCl
  • 2-Thienyl-2-dimethylaminoethyl ketone hydrochloride
  • 2-[3-(Dimethylamino)propionyl]thiophene Hydrochloride
  • 1-Propanone-3-(diMethylaMino)-1-(2-thienyl)- hydrochloride
  • 1-Propanone,3-(diMethylaMino)-1-(2-thienyl)-, hydrochloride (1:1)
  • 3-(dimethylamino)-1-(thiophen-2-yl)propan-1-one
  • 1,5-Bis(dimethylamino)-1,5-di(thiophen-2-yl)pentan-3-one hydrochloride
  • Duloxetine Impurity 18
  • Duloxetine-16
  • 3-(Dimethylamino)-1-(2-thienyl)-1-propanoneHydrochloride&gt
  • 3-(N,N-dimethylamino)-1-(thiophen-2-yl)-propan-1-one hydrochloride
  • Duloxetine Impurity 9 HCl
  • 3-Dimethyl amino-1-(2-thienyl)-1-propanone hydrochlorideQ: What is 3-Dimethyl amino-1-(2-thienyl)-1-propanone hydrochloride Q: What is the CAS Number of 3-Dimethyl amino-1-(2-thienyl)-1-propanone hydrochloride Q: What is the storage condition of 3-Dimethyl amino-1-(2-thienyl)-1-propanone hydrochloride
  • 3-(dimethylamino)-1-(2-thienyl)-1-Propanone hydrochloride (1:1)
  • Compound Fr12480
  • 3-(Dimethylamino)-1-(thiophen-2-yl)propan-1-onehydrochloride(DuloxetineImpurity)
  • 3-(dimethylamino)-1-(thiophen-2-yl)propan-1-one HCl
  • 3-(Dimethylamino)-1-(2-thienyl)propanone hydrochloride
  • 3-(Dimethylamino)-1-(thiophen-2-yl)-1-propanone HCl
  • 5424-47-5
  • C9H14ClNOS
  • C9H13NOSHCl
  • C17H25ClN2OS2