ChemicalBook > CAS DataBase List > 7-AMINO-4-METHYL-3-COUMARINYLACETIC ACID

7-AMINO-4-METHYL-3-COUMARINYLACETIC ACID

Product Name: 7-AMINO-4-METHYL-3-COUMARINYLACETIC ACID
CAS No.: 106562-32-7
Chemical Name: 7-AMINO-4-METHYL-3-COUMARINYLACETIC ACID
Synonyms: AMCA-H;AMCA blue;AMCA acid;AMCA (coumarin);AMCA Free Acid (Blue);2H-1-Benzopyran-3-acetic acid;AMCA acid *CAS#: 106562-32-7*;AMINO-METHYL-COUMARINACETICACID;7-AMINO-4-METHYL-3-COUMARINYLACETIC ACID;7-Amino-4-methylcoumarin-3-aceticAcid>
CBNumber: CB4196576
Molecular Formula: C12H11NO4
Formula Weight: 233.22
MOL File: 106562-32-7.mol

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7-AMINO-4-METHYL-3-COUMARINYLACETIC ACID Property

Boiling point:: 512.2±50.0 °C(Predicted)
Density: 1.391±0.06 g/cm3 (20 ºC 760 Torr)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: DMF: soluble
form: powder to crystal
pka: 3.80±0.10(Predicted)
color: Light yellow to Brown
Appearance: Solid
λmax: 344nm(Buffer)(lit.)
BRN: 7927205
InChI: InChI=1S/C12H11NO4/c1-6-8-3-2-7(13)4-10(8)17-12(16)9(6)5-11(14)15/h2-4H,5,13H2,1H3,(H,14,15)
InChIKey: QEQDLKUMPUDNPG-UHFFFAOYSA-N
SMILES: C1(=O)OC2=CC(N)=CC=C2C(C)=C1CC(O)=O

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
HS Code: 29322090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 08445
Product name: 7-Amino-4-methyl-3-coumarinylacetic acid
Purity: BioReagent, suitable for fluorescence, ~90% (HPLC)
Packaging: 100mg
Price: $110
Updated: 2025/07/31

Sigma-Aldrich

Product number: 08445
Product name: 7-Amino-4-methyl-3-coumarinylacetic acid
Purity: BioReagent, suitable for fluorescence, ~90% (HPLC)
Packaging: 500mg
Price: $377.3
Updated: 2025/07/31

TCI Chemical

Product number: A2820
Product name: 7-Amino-4-methylcoumarin-3-acetic Acid
Purity: >95.0%(T)
Packaging: 50mg
Price: $49
Updated: 2025/07/31

TCI Chemical

Product number: A2820
Product name: 7-Amino-4-methylcoumarin-3-acetic Acid
Purity: >95.0%(T)
Packaging: 250mg
Price: $156
Updated: 2025/07/31

Cayman Chemical

Product number: 29184
Product name: 7-Amino-4-methyl-3-coumarinylacetic Acid
Packaging: 50mg
Price: $48
Updated: 2024/03/01

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7-AMINO-4-METHYL-3-COUMARINYLACETIC ACID Chemical Properties,Usage,Production

Description

AMCA is fluorescent protein labeling agent. It contains an N-hydroxysuccinimide ester that reacts with lysine residues to form photostable amide links. Upon activation with UV light, AMCA displays emission maxima of 400-460 nm. It has commonly been used in multiplex immunophenotyping applications.

Uses

7-AMINO-4-METHYL-3-COUMARINYLACETIC ACID is a blue fluorescent dye. Its desirable properties include a relatively large Stoke's shift and resistance to photobleaching. 7-AMINO-4-METHYL-3-COUMARINYLACETIC ACID is used as contrasting probes for double and triple labeling in im

Uses

Non-Activated, Amine-Reactive, fluorescent probe

Chemical Reactivity

Primary amines (needs activation)

References

[1] H. KHALFAN. Aminomethyl coumarin acetic acid: A new fluorescent labelling agent for proteins[J]. Journal of Molecular Histology, 1986, 18 9: 497-499. DOI: 10.1007/bf01675617
[2] G L FERRI. Quadruple immunofluorescence: a direct visualization method.[J]. Journal of Histochemistry & Cytochemistry, 1997, 45 2: 155-158. DOI: 10.1177/002215549704500201
[3] P. M. NEDERLOF. Three-color fluorescence in situ hybridization for the simultaneous detection of multiple nucleic acid sequences[J]. Cytometry Part B: Clinical Cytometry, 1989, 10 1: 20-27. DOI: 10.1002/cyto.990100105
[4] ANDRé GOTHOT Jean M P Jean Claude Grosdent. A strategy for multiple immunophenotyping by image cytometry: Model studies using latex microbeads labeled with seven streptavidin-bound fluorochromes[J]. Cytometry Part A, 1996, 24 3: 214-225. DOI: 10.1002/(sici)1097-0320(19960701)24:3<214::aid-cyto4>3.0.co;2-h

Abs/Em Maxima

345/450 nm

Extinction Coefficient

19,000 cm-1M-1

Spectrally Similar Dyes

Alexa Fluor® 350, AMCA, DyLight® 350

7-AMINO-4-METHYL-3-COUMARINYLACETIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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7-AMINO-4-METHYL-3-COUMARINYLACETIC ACID Suppliers

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View Lastest Price from 7-AMINO-4-METHYL-3-COUMARINYLACETIC ACID manufacturers

Career Henan Chemical Co

Product: 7-AMINO-4-METHYL-3-COUMARINYLACETIC ACID 106562-32-7
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98% HPLC
Supply Ability: 10 tons/month
Release date: 2020-01-09

106562-32-7, 7-AMINO-4-METHYL-3-COUMARINYLACETIC ACIDRelated Search:

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AMCA (coumarin)

AMCA blue

2H-1-Benzopyran-3-acetic acid, 7-amino-4-methyl-2-oxo-

AMINO-METHYL-COUMARINACETICACID

7-AMINO-4-METHYL-3-COUMARINYLACETIC ACID BIOCHEMIKA, FOR FLUORESCENCE 90%

2-(7-amino-4-methyl-2-oxochromen-3-yl)acetic acid

AMCA-H

7-AMINO-4-METHYL-3-COUMARINYLACETIC ACID

7-AMINO-4-METHYL-2-OXO-2H-CHROMEN-3-YL ACETIC ACID

2-(7-aMino-4-Methyl-2-oxo-2H-chroMen-3-yl)acetic acid

AMCA-H [7-AMino-4-Methyl-3-couMarinylacetic acid ]

FMOC-7-AMINO-4-METHYL-3-COUMARINYLACETIC ACID

2H-1-Benzopyran-3-acetic acid

7-Amino-4-methyl-3-coumarinylacetic acid(AMCA)

AMCA acid *CAS#: 106562-32-7*

7-Amino-4-methylcoumarin-3-aceticAcid&gt

AMCA acid

7-Amino-4-methyl-2-oxo-2H-chromen-3-yl acetic acid, 90+%

2-(7-amino-4-methyl-2-oxochromen-3-yl)aceticaci

7-Amino-4-methylcoumarin-3-acetic acid, 10 mM in DMSO

AMCA Free Acid (Blue)

106562-32-7

Biochemicals and Reagents

BioChemical

Fluorescent Probes, Labels, Particles and Stains

Detection

AMCA