ChemicalBook > CAS DataBase List > N,N-Dimethyl-p-toluidine

N,N-Dimethyl-p-toluidine

Product Name
N,N-Dimethyl-p-toluidine
CAS No.
99-97-8
Chemical Name
N,N-Dimethyl-p-toluidine
Synonyms
N,N,4-Trimethylaniline;Dimethyl-p-toluidine;dimethyltoluidine;n,n-dimethyl-p-toluidin;N,N-DIMETHYL-4-TOLUIDINE;N,N-Dimethyl-p-tolylamine;N,N-DIMETHYL-4-METHYLANILINE;4,N,N-TrimethyL;N,N,4-trimethyl-;DIMETHYLTOLYLAMINE
CBNumber
CB4196682
Molecular Formula
C9H13N
Formula Weight
135.21
MOL File
99-97-8.mol
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N,N-Dimethyl-p-toluidine Property

Melting point:
-25°C
Boiling point:
211 °C(lit.)
Density 
0.937 g/mL at 25 °C(lit.)
vapor density 
>1 (vs air)
vapor pressure 
0.1 hPa (20 °C)
refractive index 
n20/D 1.546(lit.)
Flash point:
182 °F
storage temp. 
Store below +30°C.
solubility 
0.65g/l
form 
Liquid
pka
pK1:7.24(+1) (25°C)
color 
Clear yellow
explosive limit
7%
Water Solubility 
Miscible with alcohol, ether and chloroform. Immiscible with water.
BRN 
774409
Dielectric constant
3.3（20℃）
Stability:
Stable. Combustible. Incompatible with strong oxidizing agents.
InChIKey
GYVGXEWAOAAJEU-UHFFFAOYSA-N
LogP
1.729-2.81 at 35℃
CAS DataBase Reference
99-97-8(CAS DataBase Reference)
IARC
2B (Vol. 115) 2018
EPA Substance Registry System
N,N,4-Trimethylaniline (99-97-8)
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Safety

Hazard Codes 
T
Risk Statements 
23/24/25-33-52/53
Safety Statements 
28-36/37-45-61-28A-51-44-36-22-20/21
RIDADR 
1708
WGK Germany 
3
RTECS 
XU5803000
F 
8-10-23
Autoignition Temperature
425 °C
TSCA 
Yes
HS Code 
2921 43 00
HazardClass 
6.1
PackingGroup 
II
Hazardous Substances Data
99-97-8(Hazardous Substances Data)
Toxicity
LD50 orally in Rabbit: 1650 mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H330Fatal if inhaled

H373May cause damage to organs through prolonged or repeated exposure

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P314Get medical advice/attention if you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.22040
Product name
N,N-Dimethyl-p-toluidine
Purity
for synthesis
Packaging
5ML
Price
$27.1
Updated
2024/03/01
Sigma-Aldrich
Product number
8.22040
Product name
N,N-Dimethyl-p-toluidine
Purity
for synthesis
Packaging
250ML
Price
$68.2
Updated
2024/03/01
Sigma-Aldrich
Product number
8.22040
Product name
N,N-Dimethyl-p-toluidine
Purity
for synthesis
Packaging
1L
Price
$139
Updated
2024/03/01
Sigma-Aldrich
Product number
41690
Product name
4,N,N-Trimethylaniline
Purity
catalyst grade (for peroxide polymerization), ≥98.5% (GC)
Packaging
100ml
Price
$61.8
Updated
2024/03/01
Sigma-Aldrich
Product number
41690
Product name
4,N,N-Trimethylaniline
Purity
catalyst grade (for peroxide polymerization), ≥98.5% (GC)
Packaging
500ml
Price
$142
Updated
2024/03/01
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N,N-Dimethyl-p-toluidine Chemical Properties,Usage,Production

Chemical Properties

light yellow liquid

Uses

N,N-Dimethyl-4-toluidine is an amine accelerator for the polymerization of e.g. dental methacrylic restorative materials

Uses

N,N-Dimethyl-p-toluidine is used as a polymerization catalyst for polyesters, acrylate and epoxy resins. It is also used as a hardener for dental cements and in adhesives. It serves as an intermediate for photographic chemicals, in industrial glues, in artificial fingernail preparations, colorants, pharmaceuticals. It reacts with vinyl ether in the presence of copper(II) chloride gives tetrahydroquinolines. Further, it is used to accelerate polymerization of ethyl methacrylate.

Synthesis Reference(s)

Synthetic Communications, 19, p. 3051, 1989 DOI: 10.1080/00397918908052700
Tetrahedron Letters, 8, p. 1849, 1967

General Description

A clear colorless liquid with an aromatic odor. Density 0.937 g / cm3 (Lancaster) and insoluble in water. Hence floats on water. Toxic by skin absorption and inhalation. Flash point 181°F. May release toxic vapors when burned.

Air & Water Reactions

Tends to darken upon exposure to air. Insoluble in water.

Reactivity Profile

N,N-Dimethyl-p-toluidine neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. May generate hydrogen, a flammable gas, in combination with strong reducing agents such as hydrides.

Health Hazard

TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

Fire Hazard

Combustible material: may burn but does not ignite readily. When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Runoff may pollute waterways. Substance may be transported in a molten form.

Synthesis

N,N-Dimethyl-p-toluidine was prepared by reacting p-toluidine with methanol and POCl3 in autoclave heated up to 280° C for 3h.

Purification Methods

Reflux for 3hours with 2 molar equivalents of Ac2O, then fractionally distil it under reduced pressure. Alternatively, dry it over BaO, distil and store it over KOH. The picrate has m 128o (from EtOH). Methods described for N,N-dimethylaniline are applicable here. [Beilstein 12 H 902, 12 III 2026, 12 IV 1874.]

N,N-Dimethyl-p-toluidine Preparation Products And Raw materials

Raw materials

Preparation Products

Acid Violet 48
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N,N-Dimethyl-p-toluidine Suppliers

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View Lastest Price from N,N-Dimethyl-p-toluidine manufacturers

HebeiShuoshengImportandExportco.,Ltd
Product
N,N-DIMETHYL-P-TOLUIDINE 99-97-8
Price
US $6.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000KG/Month
Release date
2024-08-08
Jinan Finer Chemical Co., Ltd
Product
N,N-Dimethyl-4-methylaniline 99-97-8
Price
US $0.00/Kg/Drum
Min. Order
1KG
Purity
99%
Supply Ability
2000mt/year
Release date
2021-08-03
Hebei Longbang Technology Co., Ltd
Product
N,N-DIMETHYL-P-TOLUIDINE 99-97-8
Price
US $6.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20TONS
Release date
2024-05-11

99-97-8, N,N-Dimethyl-p-toluidineRelated Search:

N,N-DIMETHYL-M-PHENYLENEDIAMINE DIHYDROCHLORIDE N,N-DIETHYL-O-TOLUIDINE N,N-DIMETHYLBUTYRAMIDE N,N-diMethyl-2-phenylethylaMine hydrochloride (USAF EL-79) N,N-dimethyl-4-vinylaniline N,O-dimethyl-N'-nitroisourea N,N-DIETHYLSALICYLAMIDE N,N-Dibenzylethanolamine N,N-DIMETHYL-2-FLUOROANILINE N,N-dimethyl-m-phenylenediamine N,N,3,5-TETRAMETHYLANILINE 4-BROMO-3-FLUORO-N,N-DIMETHYLBENZAMIDE N,N-DIISOPROPYLBENZAMIDE N,N-Diethyl-m-toluamide N,N'-DIDODECYL DITHIOOXAMIDE N,N-DIPHENYLACETAMIDE Pigment Violet 3 4-MORPHOLINOACETOPHENONE

  • N,N,4-TRIMETHYLBENZENAMINE
  • N,N-DIMETHYL-4-METHYLANILINE
  • N,N-DIMETHYL-4-TOLUIDINE
  • N,N-DIMETHYL-PARA-TOLUIDINE
  • N,N-DIMETHYL-P-TOLUIDINE
  • Benzeneamine,N,N,4-trimethyl-
  • dimethyl-4-toluidine
  • Dimethyl-p-toluidine
  • Dimethyl-p-tolyl-amine
  • dimethyltoluidine
  • Dimetil-p-toluidina
  • N,N,4-Trimethylaniline
  • n,n,4-trimethyl-benzenamin
  • N,N-Dialkylarylamine(methylgroupinmetaposition)
  • N,N-Dialkylarylamine
  • 4,N,N-Trimethylaniline,4-Dimethylaminotoluene, N,N-Dimethyl-p-toluidine
  • 4,N,N-Trimethylanili
  • N,N-DiMethyl-p-toluidine, 99% 500GR
  • <i>N,N</i>-Dimethyl-<i>p</i>-toluidine
  • 4,N,N-Trimethylaniline catalyst grade (for peroxide polymerization), >=98.5% (GC)
  • 4,N,N-Trimethylaniline purum, >=98.0% (GC)
  • N,N,4-Trimethylaniline 4-Dimethylaminotoluene
  • N,N- two Methylp-toluidine
  • 4,N,N-TriMethylaniline 99%
  • 4,N,N-TriMethylaniline, 98%+
  • N,N,4-trimethyl-
  • <i>N</i>,<i>N</i>-Dimethyl-<i>p</i>-toluidine
  • N,N-Dimethyl-p-toluidine for synthesis
  • 4,N,N-TrimethyL
  • n,n-dimethyl-p-toluidin
  • N,N-Dimethyl-p-tolylamine
  • p-(dimethylamino)toluene
  • p,N,N-trimethylaniline
  • p-Methyl-N,N-dimethylaniline
  • p-Toluidine, N,N-dimethyl-
  • 4-DIMETHYLAMINOTOLUENE
  • 4,N,N-TRIMETHYLANILINE
  • Tetraphenylphthalicanhydride,98%
  • Benzenamine, N,N,4-trimethyl-
  • DIMETHYLPARA-TOLUIDINE
  • 4-METHYL-N,N-DIMETHYLANILINE
  • PARA-N,N-TRIMETHYLANILINE
  • 4-Dimethylaminotoluene, N,N-Dimethyl-p-toluidine
  • p-Tolyldimethylamine
  • N,N-Dimethyl-p-toluidine,99%
  • DIMETHYLTOLYLAMINE
  • N,N-Dimethyl-p-toluidine &gt
  • N,N-DIMETHYL-P-TOLUIDINE ISO 9001：2015 REACH
  • N,N-Dimethyl-p-toluidine Purity 99%
  • Diethyl pyrocarbonate 1609-47-8
  • 99-97-8
  • CH3C6H4NCH32
  • Building Blocks
  • Amines
  • C9 to C10
  • Organic Building Blocks
  • Nitrogen Compounds
  • Solvents