METHYL 4-IODO-3-METHYLBENZOATE
- Product Name
- METHYL 4-IODO-3-METHYLBENZOATE
- CAS No.
- 5471-81-8
- Chemical Name
- METHYL 4-IODO-3-METHYLBENZOATE
- Synonyms
- METHYL 4-IODO-M-TOLUATE;METHYL 4-IODO-3-METHYLBENZOATE;Methyl4-Iodo-3-methylbenzoate>4-IODO-M-TOLUIC ACID METHYL ESTER;4-Iodo-3-methylbenzoic acid methyl;4-IODO-3-METHYLBENZOIC ACID METHYL ESTER;3-methyl-4-iodobenzoic acid methyl ester;Benzoic acid, 4-iodo-3-methyl-, methyl ester;4-iodo-3-methyl-Benzoic acid methyl ester (9CI ACI);Benzoic acid, 4-iodo-3-methyl-, methyl ester (9CI, ACI)
- CBNumber
- CB4205238
- Molecular Formula
- C9H9IO2
- Formula Weight
- 276.07
- MOL File
- 5471-81-8.mol
METHYL 4-IODO-3-METHYLBENZOATE Property
- Melting point:
- 59-62°C
- Boiling point:
- 106 °C / 4mmHg
- Density
- 1.666±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- Slightly soluble in methanol.
- form
- powder to crystal
- color
- White to Light yellow to Light orange
- Sensitive
- Light Sensitive
Safety
- Risk Statements
- 36/37/38
- Safety Statements
- 24/25-37-26
- Hazard Note
- Harmful
- HS Code
- 29163990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- I0601
- Product name
- Methyl 4-Iodo-3-methylbenzoate
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $86
- Updated
- 2025/07/31
- Product number
- I0601
- Product name
- Methyl 4-Iodo-3-methylbenzoate
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $288
- Updated
- 2025/07/31
- Product number
- I708600
- Product name
- 4-Iodo-3-methylbenzoicAcidMethylEster
- Packaging
- 1g
- Price
- $970
- Updated
- 2021/12/16
- Product number
- HCH0026485
- Product name
- METHYL 4-IODO-3-METHYLBENZOATE
- Purity
- 95.00%
- Packaging
- 25G
- Price
- $1161.74
- Updated
- 2021/12/16
- Product number
- 2723-H-X1
- Product name
- Methyl 4-iodo-3-methylbenzoate
- Packaging
- 5G
- Price
- $29
- Updated
- 2021/12/16
METHYL 4-IODO-3-METHYLBENZOATE Chemical Properties,Usage,Production
Uses
Methyl 4-iodo-3-methylbenzoate is used in the synthesis of novel colchicine-derived nitrate esters as immunosuppressant agents.
Uses
METHYL 4-IODO-3-METHYLBENZOATE is used in the synthesis of novel colchicine-derived nitrate esters
Synthesis
(a) 3-Methyl-4-iodobenzoic acid: 20 g (0.132 mol) of 3-methyl-4-aminobenzoic acid 175 ml of sulfuric acid (20%) was introduced into a three-necked flask. A solution of 11.9 g (0.172 mol) of sodium nitrite in 50 ml of water was added dropwise at -10??C and the mixture was stirred for 2 hours. The solution was added dropwise to 35 g (0.211 mol) of potassium iodide 35.2 g (0.185 mol) of copper iodide and 175 ml of sulfuric acid (20%) by means of an ampoule frozen at -5??C. The mixture was stirred for eight hours, the reaction medium was filtered, the solid obtained was dissolved in ethyl acetate, washed with water, then with sodium sulfite solution, dried with magnesium sulfate and evaporated. 24.4 g (70%) of 3-methyl-4-iodobenzoic acid with a melting point of 205-10 ??C was collected.
(b) Methyl 4-iodo-3-methylbenzoate: 24.4 g (0.093 mol) of 3-methyl-4-iodobenzoic acid 250 ml of methanol was introduced into a flask and 2.5 ml of concentrated sulfuric acid was added dropwise. The mixture was refluxed for twelve hours, the reaction medium was evaporated, the residue was dissolved in ethyl acetate and water, the organic phase was decanted, dried over magnesium sulfate and evaporated. The residue was ground in methanol, filtered, and 21.9 g (85%) of the expected methyl 4-iodo-3-methylbenzoate with a melting point of 58-9 ??C was collected.
METHYL 4-IODO-3-METHYLBENZOATE Preparation Products And Raw materials
Raw materials
Preparation Products
METHYL 4-IODO-3-METHYLBENZOATE Suppliers
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View Lastest Price from METHYL 4-IODO-3-METHYLBENZOATE manufacturers
- Product
- METHYL 4-IODO-3-METHYLBENZOATE 5471-81-8
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-06-27
- Product
- METHYL 4-IODO-3-METHYLBENZOATE 5471-81-8
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 1000KGS
- Release date
- 2019-12-20