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LEUROSINE
- Product Name
- LEUROSINE
- CAS No.
- 23360-92-1
- Chemical Name
- LEUROSINE
- Synonyms
- amotin;LEUROSINE;nsc-528004;Vinleurosine;Vincristine EP Impurity F;Vincristine EP Impurity F (Leurosine);4'-Deoxy-3',4'-epoxyvincaleucoblastine, 9CI;(3'R,4'S)-3',4'-Oxy-4'-deoxyvincaleukoblastine;Vincristine Impurity 6(Vincristine EP Impurity F);4′-deoxy-3′α,4′α-epoxyvincaleukoblastine(leurosine)
- CBNumber
- CB4205283
- Molecular Formula
- C46H56N4O9
- Formula Weight
- 808.97
- MOL File
- 23360-92-1.mol
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LEUROSINE Property
- Melting point:
- 202-205℃
- Density
- 1.39
- pka
- 11.36±0.60(Predicted)
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Safety
- RIDADR
- 1544
- HazardClass
- 6.1(a)
- PackingGroup
- II
- Hazardous Substances Data
- 23360-92-1(Hazardous Substances Data)
- Toxicity
- dog,LDLo,intraperitoneal,12mg/kg (12mg/kg),GASTROINTESTINAL: NAUSEA OR VOMITINGGASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA",Eksperimental'naya Onkologiya. Experimental Oncology. Vol. 9(5), Pg. 76, 1987.
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N-Bromosuccinimide Price
TRC
- Product number
- V314520
- Product name
- Vinleurosine
- Packaging
- 10mg
- Price
- $1320
- Updated
- 2021/12/16
Arctom
- Product number
- CFN90466
- Product name
- Vinleurosine
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $833
- Updated
- 2021/12/16
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LEUROSINE Chemical Properties,Usage,Production
Description
Vinqa rosea yields this complex dimeric alkaloid which forms colourless crystals that are best purified by recrystallization from acetonitrile. It crystallizes with 8 moles of H20 and loses solvent when heated at In-5°C. It is also dextro? rotatory with [α]26D + n° (CHCI3)’ A crystalline SUlphate is known which has m.p. 238-242°C (dec.) and [α]D - 8.3° (MeOH). The N(b)-oxide is identical with pleurosine (q.v.).
Uses
Antineoplastic.
Uses
Vinleurosine is an antitumor compound derived from Vinca Rosea.
Definition
ChEBI: Leurosine is a vinca alkaloid.
References
Svoboda., J. Amer. Pharm. Assoc., 47,834 (1959)
Neuss et al., J. Amer. Chern. Soc., 81,4754 (1959)
Revised structure:
Neuss et al., Tetrahedron Lett., 783 (1968)
LEUROSINE Preparation Products And Raw materials
Raw materials
Preparation Products
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LEUROSINE Suppliers
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View Lastest Price from LEUROSINE manufacturers
Career Henan Chemical Co
- Product
- LEUROSINE 23360-92-1
- Price
- US $0.01/KG
- Min. Order
- 1KG
- Purity
- 98%; 99%
- Supply Ability
- 500g;1kg; 25kg
- Release date
- 2020-01-09
23360-92-1, LEUROSINERelated Search:
VincristineM1
4'-Deoxy Vincristine
N-Desmethylvinblastine
Vinorelbine EP Impurity G
Aspidospermidine-3-carboxylic acid, 4-(acetyloxy)-6,7-didehydro-15-[(6R,8S)-4-ethyl-1,3,6,7,8,9-hexahydro-8-(methoxycarbonyl)-2-oxido-2,6-methano-2H-azecino[4,3-b]indol-8-yl]-3-hydroxy-16-methoxy-1-methyl-, methyl ester, (2β,3β,4β,5α,12R,19α)-
4-Desacetyl Vinblastine
3',4'-Anhydrovinblastine
Vinorelbine EP Impurity H
Cophylline
desacetylnavelbine
Vinorelbine EP Impurity F
VINBLASTINE
(2R,3R)-3-AMINO-2-HYDROXYHEXANOIC ACID
LEUROSINE
(R)-3-AMINO-4-(3-METHYLPHENYL)BUTANOIC ACID HYDROCHLORIDE
3-AMINO-4-(4-METHOXY-PHENYL)-BUTYRIC ACID
(R)-3-AMINO-4-(4-METHOXYPHENYL)BUTANOIC ACID
(2S,3R)-3-AMINO-2-HYDROXY-4-PHENYLBUTYRIC ACID HYDROCHLORIDE