ChemicalBook > CAS DataBase List > FLB 131, S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochloride

FLB 131, S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochloride

Product Name
FLB 131, S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochloride
CAS No.
97612-24-3
Chemical Name
FLB 131, S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochloride
Synonyms
Eticlopride HCl;Eticlopride hydrochl;S(-)-ETICLOPRIDE HYDROCHLORIDE (POTENT A ND SELECTIVE D2 DOPAMINE;(2S)-2-{[(3-chloro-5-ethyl-6-hydroxy-2-methoxybenzoyl)amino]methyl}-1-ethylpyrrolidinium chloride;3-Chloro-5-ethyl-N-[[(2S)-1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxy-benzamidehydrochloride;Benzamide,3-chloro-5-ethyl-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-6-hydroxy-2-methoxy-,hydrochloride (1:1);FLB 131, S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochloride
CBNumber
CB42130556
Molecular Formula
C17H26Cl2N2O3
Formula Weight
377.31
MOL File
97612-24-3.mol
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FLB 131, S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochloride Property

Melting point:
144-146 °C(Solv: acetone (67-64-1))
storage temp. 
Desiccate at RT
solubility 
H2O: soluble >10mg/mL
form 
powder
color 
off-white
optical activity
[α]27/D 7.2°, c = 0.3 in methanol(lit.)
Water Solubility 
Soluble to 100 mM in water
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Safety

WGK Germany 
3
RTECS 
CV2450000
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
E101
Product name
S-(?)-Eticlopride hydrochloride
Purity
≥98% (HPLC), powder
Packaging
25mg
Price
$178
Updated
2024/03/01
Sigma-Aldrich
Product number
E101
Product name
S-(?)-Eticlopride hydrochloride
Purity
≥98% (HPLC), powder
Packaging
100mg
Price
$476
Updated
2024/03/01
Cayman Chemical
Product number
29112
Product name
Eticlopride (hydrochloride)
Packaging
5mg
Price
$68
Updated
2024/03/01
Cayman Chemical
Product number
29112
Product name
Eticlopride (hydrochloride)
Packaging
10mg
Price
$121
Updated
2024/03/01
Cayman Chemical
Product number
29112
Product name
Eticlopride (hydrochloride)
Packaging
25mg
Price
$252
Updated
2024/03/01
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FLB 131, S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochloride Chemical Properties,Usage,Production

Uses

Dopamine receptor antagonist

Uses

S-(?)-Eticlopride hydrochloride has been used in astrocyte-neuron coculture and functional magnetic resonance imaging (fMRI) experiments.

Biological Activity

Selective dopamine D 2 /D 3 receptor antagonist (K i values are 0.50 and 0.16 nM respectively). Antipsychotic.

Biochem/physiol Actions

Potent and selective D2 dopamine receptor antagonist. Eticlopride is highly specific for DAD2?receptors than pimozide or haloperidol. The gene encoding the D2 dopamine receptor (DRD2) is linked with a several disorders including Parkinson′s disease, schizophrenia, and susceptibility to alcoholism.

storage

room temperature (desiccate)

FLB 131, S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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FLB 131, S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochloride Suppliers

China 16 India 1 United Kingdom 1 United States 7 Global 25
3B Pharmachem (Wuhan) International Co.,Ltd.
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821-50328103-801 18930552037
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86-21-50328109
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3bsc@sina.com
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China
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Shanghai TaoSu Biochemical Technology Co., Ltd.
Tel
021-33632979
Fax
021-34692979
Email
info@tsbiochem.com
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China
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8065
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58
Sigma-Aldrich
Tel
021-61415566 800-8193336
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orderCN@merckgroup.com
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China
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Shanghai EFE Biological Technology Co., Ltd.
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021-65675885 18964387627
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021-65675885
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China
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ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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18818260767
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QQ 3610331285
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sales@chemegen.com
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China
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Guangzhou Younan Technology Co., Ltd
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020-82000279 18988968278
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sales@ubiochem.com
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China
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MedBioPharmaceutical Technology Inc
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021-69568360 18916172912
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order@med-bio.cn
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China
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Shanghai Universal Biotech Co.,Ltd
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13774214275
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zhouzz@univ-bio.com
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China
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InvivoChem
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13549236410
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sales@invivochem.cn
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China
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JiangSu Star Science Co.,Ltd
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sales022@b2star.com
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TargetMol Chemicals Inc.
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marketing@tsbiochem.com
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Shanghai Maclean Biochemical Technology Co., LTD
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China
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Shanghai Yingxin laboratory equipment Co., Ltd
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Shanghai Guchen Biotechnology Co., LTD
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Nantong QuanYi Biotechnology Co., Ltd
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97612-24-3, FLB 131, S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochlorideRelated Search:

Etidronate disodium S(-)-ETICLOPRIDE HYDROCHLORIDE

  • S(-)-ETICLOPRIDE HYDROCHLORIDE (POTENT A ND SELECTIVE D2 DOPAMINE
  • FLB 131, S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochloride
  • 3-Chloro-5-ethyl-N-[[(2S)-1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxy-benzamidehydrochloride
  • Eticlopride hydrochl
  • Benzamide,3-chloro-5-ethyl-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-6-hydroxy-2-methoxy-,hydrochloride (1:1)
  • (2S)-2-{[(3-chloro-5-ethyl-6-hydroxy-2-methoxybenzoyl)amino]methyl}-1-ethylpyrrolidinium chloride
  • Eticlopride HCl
  • 97612-24-3