5-AMINO-2-FLUOROBENZONITRILE
- Product Name
- 5-AMINO-2-FLUOROBENZONITRILE
- CAS No.
- 77123-60-5
- Chemical Name
- 5-AMINO-2-FLUOROBENZONITRILE
- Synonyms
- 3-ETHYNYL-4-FLUOROANILINE;2-FLUORO-5-AMINOBENZONITRILE;3-Ethynyl-4-fluorobenzenamine;Benzenamine, 3-ethynyl-4-fluoro-;5-AMINO-2-FLUOROBENZONITRILE 95%min;3-Ethynyl-4-fluoroaniline - [E47969];Benzenamine, 3-ethynyl-4-fluoro- (9CI);5-AMINO-2-FLUOROBENZONITRILE ISO 9001：2015 REACH
- CBNumber
- CB4217806
- Molecular Formula
- C8H6FN
- Formula Weight
- 135.14
- MOL File
- 77123-60-5.mol
5-AMINO-2-FLUOROBENZONITRILE Property
- Melting point:
- 92-96 °C(lit.)
- Boiling point:
- 247℃
- Density
- 1.16
- Flash point:
- 114℃
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 3.73±0.10(Predicted)
- Appearance
- Light yellow to yellow Liquid
N-Bromosuccinimide Price
- Product number
- E932653
- Product name
- 3-Ethynyl-4-fluoroaniline
- Packaging
- 250mg
- Price
- $165
- Updated
- 2021/12/16
- Product number
- E47969
- Product name
- 3-Ethynyl-4-fluoroaniline
- Purity
- 95+%
- Packaging
- 100mg
- Price
- $50
- Updated
- 2021/12/16
- Product number
- E47969
- Product name
- 3-Ethynyl-4-fluoroaniline
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $90
- Updated
- 2021/12/16
- Product number
- AS34493
- Product name
- 3-Ethynyl-4-fluoroaniline
- Purity
- 97+%
- Packaging
- 250mg
- Price
- $115
- Updated
- 2021/12/16
- Product number
- E47969
- Product name
- 3-Ethynyl-4-fluoroaniline
- Purity
- 95+%
- Packaging
- 1g
- Price
- $160
- Updated
- 2021/12/16
5-AMINO-2-FLUOROBENZONITRILE Chemical Properties,Usage,Production
Synthesis
77123-63-8
77123-60-5
Step 3d. Synthesis of 3-ethynyl-4-fluoroaniline (Compound 0605): Compound 0604 (1.49 g) obtained above was dissolved in 20 mL of methanol, 100 mg of potassium hydroxide was added and the reaction was stirred at room temperature overnight. Upon completion of the reaction, the reaction solution was concentrated, diluted to neutral with water and subsequently extracted with ether. The organic phases were combined, dried with anhydrous magnesium sulfate, filtered and concentrated to give 3-alkynyl-4-fluoroaniline 0605 (1.49 g, 85% yield) as a brown oil. The molecular weight of the product was 136 [M + 1]+ by LCMS. The obtained product can be directly used in the subsequent reaction without further purification.
References
[1] Patent: US2009/111772, 2009, A1. Location in patent: Page/Page column 77
[2] Patent: WO2008/33747, 2008, A2. Location in patent: Page/Page column 139
[3] Patent: US2009/76022, 2009, A1. Location in patent: Page/Page column 78
[4] Journal of Organic Chemistry, 1981, vol. 46, # 11, p. 2280 - 2286
[5] Patent: JP5680638, 2015, B2. Location in patent: Paragraph 0347-0348
5-AMINO-2-FLUOROBENZONITRILE Preparation Products And Raw materials
Raw materials
Preparation Products
5-AMINO-2-FLUOROBENZONITRILE Suppliers
- Tel
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- info@chemsworth.com
- Country
- India
- ProdList
- 6700
- Advantage
- 30
- Tel
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- sales@ajchem.in
- Country
- India
- ProdList
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- Advantage
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View Lastest Price from 5-AMINO-2-FLUOROBENZONITRILE manufacturers
- Product
- 3-Ethynyl-4-fluoroaniline 77123-60-5
- Price
- US $0.00-0.00/KG
- Min. Order
- 10mg
- Purity
- 99%HPLC
- Supply Ability
- 2000tons
- Release date
- 2020-01-17
- Product
- 5-AMINO-2-FLUOROBENZONITRILE 77123-60-5
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2020-01-08