ChemicalBook > CAS DataBase List > (5aS)-2,3,5aβ,6,7,8-Hexahydro-1H,5H-dipyrrolo[1,2-a:1',2'-d]pyrazine-5,10(10aβH)-dione

(5aS)-2,3,5aβ,6,7,8-Hexahydro-1H,5H-dipyrrolo[1,2-a:1',2'-d]pyrazine-5,10(10aβH)-dione

Product Name
(5aS)-2,3,5aβ,6,7,8-Hexahydro-1H,5H-dipyrrolo[1,2-a:1',2'-d]pyrazine-5,10(10aβH)-dione
CAS No.
6708-06-1
Chemical Name
(5aS)-2,3,5aβ,6,7,8-Hexahydro-1H,5H-dipyrrolo[1,2-a:1',2'-d]pyrazine-5,10(10aβH)-dione
Synonyms
Cyclo(Pro-Pro-);Cyclo(L-Pro-L-Pro-);L-Proline Anhydride;Aliskiren Impurity 50;cis-cyclo(?-Pro-?-Pro);Vildagliptin Impurity 23;Vildagliptin Impurity 60;Vildagliptin impurities12;Vildagliptin Dipyrrolidine Impurity;Proline cyclization impurity (mixed isomers)
CBNumber
CB42182070
Molecular Formula
C10H14N2O2
Formula Weight
194.23
MOL File
6708-06-1.mol
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(5aS)-2,3,5aβ,6,7,8-Hexahydro-1H,5H-dipyrrolo[1,2-a:1',2'-d]pyrazine-5,10(10aβH)-dione Property

Melting point:
146-148 °C
Boiling point:
413.5±25.0 °C(Predicted)
Density 
1.32±0.1 g/cm3(Predicted)
pka
-0.85±0.20(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Arctom
Product number
CFN90270
Product name
Cyclo(Pro-Pro)
Packaging
10mg
Price
$332
Updated
2021/12/16
AccelPharmtech
Product number
E0942
Product name
octahydro-5H,10H-Dipyrrolo[1,2-a:1',2'-d]pyrazine-5,10-dione
Purity
97.00%
Packaging
5G
Price
$1080
Updated
2021/12/16
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(5aS)-2,3,5aβ,6,7,8-Hexahydro-1H,5H-dipyrrolo[1,2-a:1',2'-d]pyrazine-5,10(10aβH)-dione Chemical Properties,Usage,Production

Uses

L-Proline Anhydride is an impurity of Vildagliptin (V305000), a class of oral anti-hyperglycemic agents that inhibit dipeptidyl peptidase 4 (DPP-4), which can act as a serine exopeptidase. Aside from their use in type 2 diabetes, gliptins have positive cardiovascular and anti-inflammtatory effects. Antidiabetic.

(5aS)-2,3,5aβ,6,7,8-Hexahydro-1H,5H-dipyrrolo[1,2-a:1',2'-d]pyrazine-5,10(10aβH)-dione Preparation Products And Raw materials

Raw materials

Preparation Products

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(5aS)-2,3,5aβ,6,7,8-Hexahydro-1H,5H-dipyrrolo[1,2-a:1',2'-d]pyrazine-5,10(10aβH)-dione Suppliers

SynZeal Research Pvt Ltd
Tel
--
Fax
--
Email
standards@synzeal.com
Country
India
ProdList
6514
Advantage
58
Pharmaffiliates Analytics and Synthetics P. Ltd
Tel
--
Fax
--
Email
mktg@pharmaffiliates.com
Country
India
ProdList
6739
Advantage
58

6708-06-1, (5aS)-2,3,5aβ,6,7,8-Hexahydro-1H,5H-dipyrrolo[1,2-a:1',2'-d]pyrazine-5,10(10aβH)-dioneRelated Search:


  • (5aS,10aS)-Hexahydro-1H,5H-dipyrrolo[1,2-a:1',2'-d]pyrazine-5,10(10aH)-dione
  • (5aS,10aS)-Octahydro-5H,10H-dipyrrolo[1,2-a:1',2'-d]pyrazine-5,10-dione
  • 1,2,3,5aβ,6,7,8,10aβ-Octahydro-5H,10H-dipyrrolo[1,2-a:1',2'-d]pyrazine-5,10-dione
  • Cyclo(L-Pro-L-Pro-)
  • Cyclo(Pro-Pro-)
  • Vildagliptin Impurity 60
  • Vildagliptin Impurity 23
  • Octahydro-5H,10H-Dipyrrolo[1,2-a:1',2'-d]pyrazine-5,10-dione
  • Vildagliptin Impurity 17/Vildagliptin Dipyrrolidine Impurity/octahydro-5H,10H-dipyrrolo[1,2-a:1',2'-d]pyrazine-5,10-dione
  • Vildagliptin Dipyrrolidine Impurity
  • 1,7-diazatricyclo[7.3.0.03,7]dodecane-2,8-dione
  • 5H,10H-Dipyrrolo[1,2-a:1',2'-d]pyrazine-5,10-dione, octahydro-
  • L-Proline Anhydride
  • Vildagliptin impurities12
  • Pyroglutamic acid lactam impurity (mixed isomers)
  • cis-cyclo(?-Pro-?-Pro)
  • Aliskiren Impurity 50
  • Proline cyclization impurity (mixed isomers)
  • Octahydro-5H,10H-dipyrrolo[1,2-a:1',2'-d]pyrazine-5,10-dione
  • 6708-06-1