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Dichloroacetyl chloride

Product Name
Dichloroacetyl chloride
CAS No.
79-36-7
Chemical Name
Dichloroacetyl chloride
Synonyms
2,2-DICHLOROACETYL CHLORIDE;CHCl2COCl;2,2-dichloroac;2,2-dichloroacetyl;Dichloroacetyl chlor;Dichloracetylchlorid;DichloroacetylChoride;DICHLORACETYL CHLORIDE;dichloro-acetylchlorid;DICHLOROACETYL CHLORIDE
CBNumber
CB0153797
Molecular Formula
C2HCl3O
Formula Weight
147.39
MOL File
79-36-7.mol
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Dichloroacetyl chloride Property

Melting point:
<25 °C
Boiling point:
107-108 °C (lit.)
Density 
1.532 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.46(lit.)
Flash point:
66 °C
storage temp. 
2-8°C
solubility 
Chloroform, Hexanes
form 
Liquid
color 
Clear colorless to light yellow
Specific Gravity
1.537 (20/4℃)
Water Solubility 
MAY DECOMPOSE
Sensitive 
Moisture Sensitive
Merck 
14,3053
BRN 
1209426
Stability:
Stable. Combustible. Incompatible with water, alcohols and oxidizing agents. Fumes in air.
InChIKey
FBCCMZVIWNDFMO-UHFFFAOYSA-N
CAS DataBase Reference
79-36-7(CAS DataBase Reference)
NIST Chemistry Reference
Acetyl chloride, dichloro-(79-36-7)
EPA Substance Registry System
Dichloroacetyl chloride (79-36-7)
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Safety

Hazard Codes 
C,N
Risk Statements 
35-50
Safety Statements 
9-26-45-61
RIDADR 
UN 1765 8/PG 2
WGK Germany 
2
RTECS 
AO6650000
19-21
Hazard Note 
Corrosive/Moisture Sensitive
TSCA 
Yes
HazardClass 
8
PackingGroup 
II
HS Code 
29159000
Hazardous Substances Data
79-36-7(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

H350May cause cancer

H400Very toxic to aquatic life

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
D55008
Product name
Dichloroacetyl chloride
Purity
98%
Packaging
100g
Price
$71
Updated
2024/03/01
Sigma-Aldrich
Product number
D55008
Product name
Dichloroacetyl chloride
Purity
98%
Packaging
5g
Price
$37
Updated
2023/06/20
TCI Chemical
Product number
D0313
Product name
Dichloroacetyl Chloride
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$28
Updated
2024/03/01
TCI Chemical
Product number
D0313
Product name
Dichloroacetyl Chloride
Purity
>98.0%(GC)(T)
Packaging
500g
Price
$91
Updated
2024/03/01
Alfa Aesar
Product number
B22296
Product name
Dichloroacetyl chloride, 97%
Packaging
100g
Price
$31.65
Updated
2024/03/01
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Dichloroacetyl chloride Chemical Properties,Usage,Production

Chemical Properties

Dichloroacetyl chloride (DCAC) is a colourless to light yellow fuming liquid with an acrid, penetrating odor. It is irritating to the eyes and mucous membranes (HSDB 2003b). DCAC is insoluble in water, but decomposes quickly to form HCl and dichloroacetic acid (t1/2 of hydrolysis of 0.0023 seconds in water at 25°C, and 0.2 seconds in 89.1:10.9 water-acetone at -20°C (Prager et al. 2001, Ugi and Beck 1961).

Uses

Dichloroacetyl Chloride is a reagent used in the synthesis of substituted benzothiazoles exhibiting antitumor and anticancer activity.

Preparation

Dichloroacetyl chloride can be synthesized by the reaction of dichloroacetic acid and chlorosulfonic acid. Or from the oxidation of trichloroethylene. Trichloroethylene and azobisisobutyronitrile (catalyst) were heated to 100°C, and oxygen was introduced to react under 0.6MPa pressure, maintaining the oil bath temperature at 110°C, and reacted for 10h, The product dichloroacetyl chloride is distilled off under normal pressure.

Definition

ChEBI: Dichloroacetyl chloride is the acyl chloride obtained by displacement of the hydroxy group of dichloroacetic acid by chloride. It has a role as a hapten. It derives from a dichloroacetic acid.

General Description

Dichloroacetyl chloride is a colorless liquid with a pungent odor. Flash point 151°F Boiling point 107-108°F. Vapors are irritating to the eyes and mucous membranes. Corrosive to metals and tissue.

Air & Water Reactions

Fumes in air. Decomposed by water to dichloroacetic acid and hydrochloric acid, both corrosive, with release of heat. (NIP).

Reactivity Profile

Solutions in acetone are stable for less than two hours and fresh solution should be prepared before each use (NIP). May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291].

Health Hazard

TOXIC; inhalation, ingestion or contact (skin, eyes) with vapors, dusts or substance may cause severe injury, burns or death. Contact with molten substance may cause severe burns to skin and eyes. Reaction with water or moist air will release toxic, corrosive or flammable gases. Reaction with water may generate much heat that will increase the concentration of fumes in the air. Fire will produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

Fire Hazard

Combustible material: may burn but does not ignite readily. Substance will react with water (some violently) releasing flammable, toxic or corrosive gases and runoff. When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapors may travel to source of ignition and flash back. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated or if contaminated with water.

Safety Profile

Questionable carcinogen with experimental tumorigenic data. Moderately toxic by ingestion, inhalation, and skin contact. Corrosive to the skin, eyes, and mucous membranes. Combustible when exposed to heat or flame. When heated to decomposition it emits toxic fumes of Cl-. See also CHLORIDES.

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Dichloroacetyl chloride Suppliers

Qingdao Dexin Chemical Co. LTD
Tel
18560810705 18560810705
Email
354907727@qq.com
Country
China
ProdList
234
Advantage
58
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12438
Advantage
60
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9414
Advantage
66
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
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View Lastest Price from Dichloroacetyl chloride manufacturers

Hebei Chuanghai Biotechnology Co,.LTD
Product
Isoamyl acetate 79-36-7
Price
US $10.70/kg
Min. Order
10kg
Purity
99%
Supply Ability
10000kg
Release date
2024-08-20
Hebei Weibang Biotechnology Co., Ltd
Product
Dichloroacetyl chloride 79-36-7
Price
US $9.90/KG
Min. Order
1KG
Purity
99%
Supply Ability
5tons
Release date
2021-10-21
Henan Fengda Chemical Co., Ltd
Product
Dichloroacetyl chloride 79-36-7
Price
US $50.00-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2023-12-22

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