ChemicalBook > CAS DataBase List > Dichloroacetyl chloride

Dichloroacetyl chloride

Product Name
Dichloroacetyl chloride
CAS No.
79-36-7
Chemical Name
Dichloroacetyl chloride
Synonyms
2,2-DICHLOROACETYL CHLORIDE;CHCl2COCl;2,2-dichloroac;2,2-dichloroacetyl;Dichloroacetyl chlor;Dichloracetylchlorid;DichloroacetylChoride;DICHLORACETYL CHLORIDE;dichloro-acetylchlorid;DICHLOROACETYL CHLORIDE
CBNumber
CB0153797
Molecular Formula
C2HCl3O
Formula Weight
147.39
MOL File
79-36-7.mol
More
Less

Dichloroacetyl chloride Property

Melting point:
<25 °C
Boiling point:
107-108 °C (lit.)
Density 
1.532 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.46(lit.)
Flash point:
66 °C
storage temp. 
2-8°C
solubility 
Chloroform, Hexanes
form 
Liquid
color 
Clear colorless to light yellow
Specific Gravity
1.537 (20/4℃)
Water Solubility 
MAY DECOMPOSE
Sensitive 
Moisture Sensitive
Merck 
14,3053
BRN 
1209426
Stability:
Stable. Combustible. Incompatible with water, alcohols and oxidizing agents. Fumes in air.
InChIKey
FBCCMZVIWNDFMO-UHFFFAOYSA-N
CAS DataBase Reference
79-36-7(CAS DataBase Reference)
NIST Chemistry Reference
Acetyl chloride, dichloro-(79-36-7)
EPA Substance Registry System
Dichloroacetyl chloride (79-36-7)
More
Less

Safety

Hazard Codes 
C,N
Risk Statements 
35-50
Safety Statements 
9-26-45-61
RIDADR 
UN 1765 8/PG 2
WGK Germany 
2
RTECS 
AO6650000
F 
19-21
Hazard Note 
Corrosive/Moisture Sensitive
TSCA 
Yes
HazardClass 
8
PackingGroup 
II
HS Code 
29159000
Hazardous Substances Data
79-36-7(Hazardous Substances Data)
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

H350May cause cancer

H400Very toxic to aquatic life

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
D55008
Product name
Dichloroacetyl chloride
Purity
98%
Packaging
100g
Price
$71
Updated
2024/03/01
Sigma-Aldrich
Product number
D55008
Product name
Dichloroacetyl chloride
Purity
98%
Packaging
5g
Price
$37
Updated
2023/06/20
TCI Chemical
Product number
D0313
Product name
Dichloroacetyl Chloride
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$28
Updated
2024/03/01
TCI Chemical
Product number
D0313
Product name
Dichloroacetyl Chloride
Purity
>98.0%(GC)(T)
Packaging
500g
Price
$91
Updated
2024/03/01
Alfa Aesar
Product number
B22296
Product name
Dichloroacetyl chloride, 97%
Packaging
100g
Price
$31.65
Updated
2024/03/01
More
Less

Dichloroacetyl chloride Chemical Properties,Usage,Production

Chemical Properties

Dichloroacetyl chloride (DCAC) is a colourless to light yellow fuming liquid with an acrid, penetrating odor. It is irritating to the eyes and mucous membranes (HSDB 2003b). DCAC is insoluble in water, but decomposes quickly to form HCl and dichloroacetic acid (t1/2 of hydrolysis of 0.0023 seconds in water at 25°C, and 0.2 seconds in 89.1:10.9 water-acetone at -20°C (Prager et al. 2001, Ugi and Beck 1961).

Uses

Dichloroacetyl Chloride is a reagent used in the synthesis of substituted benzothiazoles exhibiting antitumor and anticancer activity.

Preparation

Dichloroacetyl chloride can be synthesized by the reaction of dichloroacetic acid and chlorosulfonic acid. Or from the oxidation of trichloroethylene. Trichloroethylene and azobisisobutyronitrile (catalyst) were heated to 100°C, and oxygen was introduced to react under 0.6MPa pressure, maintaining the oil bath temperature at 110°C, and reacted for 10h, The product dichloroacetyl chloride is distilled off under normal pressure.

Definition

ChEBI: Dichloroacetyl chloride is the acyl chloride obtained by displacement of the hydroxy group of dichloroacetic acid by chloride. It has a role as a hapten. It derives from a dichloroacetic acid.

General Description

Dichloroacetyl chloride is a colorless liquid with a pungent odor. Flash point 151°F Boiling point 107-108°F. Vapors are irritating to the eyes and mucous membranes. Corrosive to metals and tissue.

Air & Water Reactions

Fumes in air. Decomposed by water to dichloroacetic acid and hydrochloric acid, both corrosive, with release of heat. (NIP).

Reactivity Profile

Solutions in acetone are stable for less than two hours and fresh solution should be prepared before each use (NIP). May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291].

Health Hazard

TOXIC; inhalation, ingestion or contact (skin, eyes) with vapors, dusts or substance may cause severe injury, burns or death. Contact with molten substance may cause severe burns to skin and eyes. Reaction with water or moist air will release toxic, corrosive or flammable gases. Reaction with water may generate much heat that will increase the concentration of fumes in the air. Fire will produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

Fire Hazard

Combustible material: may burn but does not ignite readily. Substance will react with water (some violently) releasing flammable, toxic or corrosive gases and runoff. When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapors may travel to source of ignition and flash back. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated or if contaminated with water.

Safety Profile

Questionable carcinogen with experimental tumorigenic data. Moderately toxic by ingestion, inhalation, and skin contact. Corrosive to the skin, eyes, and mucous membranes. Combustible when exposed to heat or flame. When heated to decomposition it emits toxic fumes of Cl-. See also CHLORIDES.

Dichloroacetyl chloride Preparation Products And Raw materials

Raw materials

2,2'-Azobis(2-methylpropionitrile) Oxygen Trichloroethylene Dichloroacetic acid Aluminum chloride Chlorosulfonic acid

Preparation Products

Tetrachlorvinphos HEPTENOPHOS Fluorochloridone Trichloroacetyl chloride 4'-Hydroxy-3'-methylacetophenone
More
Less

Dichloroacetyl chloride Suppliers

Americas 1 Belgium 3 Canada 1 China 232 Europe 1 Finland 1 France 3 Germany 10 India 15 Japan 6 Slovakia 1 South Korea 1 Spain 1 Switzerland 5 The Netherlands 1 Ukraine 1 United Kingdom 17 United States 41 Global 341
Zouping Mingxing Chemical Co.,Ltd
Tel
18806491188
Email
lzkysong@163.com
Country
China
ProdList
20
Advantage
58
Qingdao Dexin Chemical Co. LTD
Tel
15624488783
Email
290898708@qq.com
Country
China
ProdList
107
Advantage
58
Dexin Chemical (Shandong) Co., LTD
Tel
18560864701
Email
957395144@qq.com
Country
China
ProdList
194
Advantage
58
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169097
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12458
Advantage
60
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9984
Advantage
60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9551
Advantage
66
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696;
Email
info@hanhongsci.com
Country
China
ProdList
42982
Advantage
64
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32344
Advantage
50
Shandong Xiya Chemical Co., Ltd
Tel
13355009207 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18739
Advantage
57
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12990
Advantage
57
BEST-REAGENT
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11726
Advantage
57
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9823
Advantage
79
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11714
Advantage
57
Chengdu Ai Keda Chemical Technology Co., Ltd.
Tel
4008-755-333 18080918076
Fax
028-86757656
Email
800078821@qq.com
Country
China
ProdList
9725
Advantage
55
Shanghai civi chemical technology co.,Ltd
Tel
86-21-34053660
Fax
86-21-34053661
Email
sale@labgogo.com
Country
China
ProdList
9872
Advantage
52
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17779
Advantage
75
Beijing innoChem Science & Technology Co.,Ltd.
Tel
400-810-7969 010-59572699
Fax
010-59572688
Email
ningzi.li@inno-chem.com.cn
Country
China
ProdList
6139
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
18216
Advantage
56
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
18521735133 18521732826;
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25015
Advantage
65
Cantotech Chemicals, Ltd.
Tel
86-0755-86635001
Fax
86-0755-22642228
Email
cantotech@126.com
Country
China
ProdList
4576
Advantage
55
Zouping Mingxing Chemical Co.,Ltd.
Tel
86-13605431940 13605431940
Fax
0086-0543-2240079
Email
zpmxchemical@126.com
Country
China
ProdList
2002
Advantage
62
Wuxi Zhangkun Biochemical Technology Co., Ltd.
Tel
+86 0510-85629785
Fax
+86 0510-85625359
Country
China
ProdList
2331
Advantage
58
Shanghai Meishui Chemical Technology Co., Ltd
Tel
021-60549325 18616193163
Fax
021-33250306
Country
China
ProdList
4528
Advantage
56
Shanghai JONLN Reagent Co., Ltd.
Tel
400-0066400 13621662912
Fax
021-55660885
Email
422131432@qq.com
Country
China
ProdList
9986
Advantage
55
Huainan Kedi Chemical Factory
Tel
0554-2106669
Fax
0554-2666215
Email
sales1@kedichem.com
Country
China
ProdList
4928
Advantage
55
RiZhao LiDeShi Chemical Co., Ltd.
Tel
010-51268198
Fax
010-63833209
Email
leadershipchem@126.com
Country
China
ProdList
2549
Advantage
58
Mei Lan Industrial (Shanghai) Co., Ltd.
Tel
021-58958189
Fax
021-58957967
Email
wouchina@126.com
Country
China
ProdList
2671
Advantage
55
Shanghai ideal Industrial Co., Ltd.
Tel
021-58957966 18930537195
Fax
021-60899437
Email
wouchina@126.com
Country
China
ProdList
3033
Advantage
58
Chengdu HuaXia Chemical Reagent Co. Ltd
Tel
400-1166-196 13458535857
Fax
QQ：800101999
Email
cdhxsj@163.com
Country
China
ProdList
13358
Advantage
58
GuangTuo Chemical (Shanghai) Co., Ltd.
Tel
021-60899189-8001 18918189673
Fax
021-60899304
Email
gtchem@126.com
Country
China
ProdList
2661
Advantage
58
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15185
Advantage
58
Credit-Chem Co., Ltd.
Tel
400-821-5857 021-64326257
Fax
021-64393586 QQ;2798200800
Email
credit-chem@foxmail.com
Country
China
ProdList
5223
Advantage
58
Shanghai Macklin Biochemical Co.,Ltd.
Tel
15221275939 15221275939
Fax
021-50706099
Email
shenlinxing@macklin.cn
Country
China
ProdList
15878
Advantage
55
SHANGHAI BANGCHENG CHEMICAL Co.,Ltd.
Tel
021-69106960 13701823733
Fax
021-69106780
Email
13701823733@163.com
Country
China
ProdList
4775
Advantage
60
Shanghai QianJin Chemical Technology Co., Ltd
Tel
021-20900665 17321230821
Fax
021-20900665
Email
2986274987@qq.com
Country
China
ProdList
981
Advantage
55
Shanghai YouPeng Chemical Co. Ltd.
Tel
021-69005955 13701776567
Fax
021-69005775
Email
youpengchem@163.com
Country
China
ProdList
4303
Advantage
56
Shanghai TongYuan Chemical Co., Ltd.
Tel
021-021-69182866 13701855675
Fax
021-69182022
Email
tongyuanchem@126.com
Country
China
ProdList
4331
Advantage
58
Shanghai Kaisai Chemical Co., Ltd
Tel
021-33516722 13701817765
Fax
021-33516776
Email
kaisaichem@163.com
Country
China
ProdList
4751
Advantage
58
Shanghai LanRun Chemical Co., Ltd.
Tel
021-69515658 ; 69515628 13701998368
Fax
021-69515998
Email
longrunchem@163.com
Country
China
ProdList
3920
Advantage
50
Shanghai Rolead Chemical Technology Co., Ltd.
Tel
021-69992220 13701886816
Fax
021-69992237
Email
roleadchem@163.com
Country
China
ProdList
4759
Advantage
50
Shanghai Kangtuo Chemical Co., Ltd.
Tel
021-69185552 13701777608
Fax
021-69186006
Email
kangtuochem@163.com
Country
China
ProdList
4369
Advantage
55
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51471
Advantage
80
Giant chemicals
Tel
028-85434334 18108076537
Fax
QQ：245797092
Email
market@gianthx.com
Country
China
ProdList
4512
Advantage
56
Chengdu Research Accelerators Technology Co., Ltd.
Tel
028-64353063
Fax
028-64353063 QQ:784253935
Email
reacchemical@163.com
Country
China
ProdList
5259
Advantage
58
Chengdu RunZeBenTu Chemical Co., Ltd
Tel
028-88469284 18000562381
Email
rzbtsj@163.com
Country
China
ProdList
9958
Advantage
56
Nanjing Vital Chemical Co., Ltd.
Tel
025-87193546 18652950785
Fax
025-87193546
Email
chemweiao@163.com
Country
China
ProdList
9030
Advantage
60
More
Less

View Lastest Price from Dichloroacetyl chloride manufacturers

Henan Fengda Chemical Co., Ltd
Product
Dichloroacetyl chloride 79-36-7
Price
US $50.00-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2023-12-22
Hebei Duling International Trade Co. LTD
Product
Dichloroacetyl chloride 79-36-7
Price
US $3.90/kg
Min. Order
1kg
Purity
99%
Supply Ability
200 tons
Release date
2022-10-25
Hebei Guanlang Biotechnology Co,.LTD
Product
Dichloroacetyl chloride 79-36-7
Price
US $10.70/Kg/Drum
Min. Order
10g
Purity
99%
Supply Ability
10000kg
Release date
2021-08-06

79-36-7, Dichloroacetyl chlorideRelated Search:

Sodium chloride Polyvinyl chloride Mepiquat chloride Ammonium chloride Choline chloride (2,4-DICHLORO-PHENYL)-ACETYL CHLORIDE Dichloroacetamide Benzyl chloride Chloroacetyl chloride Calcium chloride 3-Acetyl-2,5-dichlorothiophene 2-Pyrrolidinecarbonitrile,1-acetyl-,(2S)-(9CI) Vildagliptin Impurity 25 Vildagliptin Impurity 6 1-Adamantanol Vildagliptin IMpurity 2 (Mixture of DiastereoMers) N-acetic acid-1-aMino-3-adaMantanol Vildagliptin Impurity 19

  • 2,2-DICHLOROACETYL CHLORIDE
  • DICHLOROETHANOYL CHLORIDE
  • DICHLORACETYL CHLORIDE
  • DICHLOROACETIC ACID CHLORIDE
  • DICHLOROACETYL CHLORIDE
  • alpha,alpha-dichloroacetyl chloride
  • Acetyl chloride, 2,2-dichloro-
  • 2,2-dichloroacetyl
  • 2,2-dichloroacetylchloride[qr]
  • Acetylchloride,dichloro-
  • acetylchloride,dichloro-[qr]
  • alpha,alpha-dichloroacetylchloride[qr]
  • CHCl2COCl
  • Chlorid kyseliny dichloroctove
  • chloridkyselinydichloroctove
  • Chlorure de dichloracetyle
  • 2,2-Dichloroacetic acid chloride
  • Dichloroethanoic acid chloride
  • DICHLOROACETYL CHLORIDE FOR SYNTHESIS
  • Dichloroacetyl chlor
  • Dichloroacetyl chloride, 97% 100ML
  • Dichloroacetyl chloride, 97% 500ML
  • 2,2-dichloroac
  • Twochloroacetyl chloride
  • chlorurededichloracetyle
  • chlorurededichloracetyle[french][qr]
  • dichloro-acetylchlorid
  • dichloroethanoylchloride[qr]
  • Dichloroacetylchloride,97%
  • DichloroacetylChoride
  • Dichloracetylchlorid
  • Dichloroacetyl Chloride &gt
  • Dichloroacetyl Chloride (DCAC)
  • Vildagliptin Impurity 47
  • 79-36-7
  • 73-36-7
  • Cl2CHCOCl
  • ACID CHLORIDE
  • Organic Building Blocks
  • Acid Halides
  • Building Blocks
  • Carbonyl Compounds
  • Pyridines
  • Organic Building Blocks
  • Pharmaceutical Intermediates
  • Organics
  • Acid Halides
  • Carbonyl Compounds