METHYL 4-FORMYL-1-METHYL-1H-PYRROLE-2-CARBOXYLATE
- Product Name
- METHYL 4-FORMYL-1-METHYL-1H-PYRROLE-2-CARBOXYLATE
- CAS No.
- 67858-47-3
- Chemical Name
- METHYL 4-FORMYL-1-METHYL-1H-PYRROLE-2-CARBOXYLATE
- Synonyms
- BUTTPARK 96\50-36;4-Formyl-2-methoxycarbonyl-N-methylpyrrole;Methyl 4-Formyl-1-methylpyrrole-2-carboxylate;METHYL 4-FORMYL-1-METHYL-1H-PYRROLE-2-CARBOXYLATE;methyl 4-formyl-1-methyl-1H-pyrrole-2-carboxylate 98%;Methyl 4-formyl-1-methyl-1h-pyrrole-2-carboxylate, 95+%;4-formyl-1-methyl-1H-Pyrrole-2-carboxylic acid methyl ester;1H-Pyrrole-2-carboxylic acid, 4-formyl-1-methyl-, methyl ester
- CBNumber
- CB4219143
- Molecular Formula
- C8H9NO3
- Formula Weight
- 167.16
- MOL File
- 67858-47-3.mol
METHYL 4-FORMYL-1-METHYL-1H-PYRROLE-2-CARBOXYLATE Property
- Melting point:
- 100 °C
- Boiling point:
- 293.1±25.0 °C(Predicted)
- Density
- 1.16±0.1 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- -9.84±0.70(Predicted)
- Appearance
- White to off-white Solid
Safety
- HazardClass
- IRRITANT
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- M450690
- Product name
- methyl4-formyl-1-methyl-1H-pyrrole-2-carboxylate
- Packaging
- 25mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- 4H23-1-5T
- Product name
- Methyl 4-formyl-1-methyl-1H-pyrrole-2-carboxylate
- Packaging
- 250mg
- Price
- $92
- Updated
- 2021/12/16
- Product number
- 0454AC
- Product name
- Methyl4-formyl-1-methyl-1H-pyrrole-2-carboxylate
- Packaging
- 250mg
- Price
- $141
- Updated
- 2021/12/16
- Product number
- 045457
- Product name
- Methyl 4-formyl-1-methyl-1H-pyrrole-2-carboxylate
- Purity
- >95%
- Packaging
- 500mg
- Price
- $255
- Updated
- 2021/12/16
- Product number
- 045457
- Product name
- Methyl 4-formyl-1-methyl-1H-pyrrole-2-carboxylate
- Purity
- >95%
- Packaging
- 1g
- Price
- $385
- Updated
- 2021/12/16
METHYL 4-FORMYL-1-METHYL-1H-PYRROLE-2-CARBOXYLATE Chemical Properties,Usage,Production
Synthesis
37619-24-2
4885-02-3
67858-47-3
AlCl3 (21.08 g, 158.1 mmol) was slowly added at -25 °C in a mixed solvent of 1,2-dichloroethane (100 mL) and nitromethane (100 mL) as methyl 1-methylpyrrole-2-carboxylate (10 g, 71.86 mmol) and 1,1-dichlorodimethyl ether (8.26 g, 71.86 mmol). The reaction mixture was stirred continuously at -25 °C for 0.5 hours. Upon completion of the reaction, the mixture was carefully poured into ice water (100 mL) to quench the reaction. Subsequently, the organic layer was separated by extraction with dichloromethane (100 mL) and water (100 mL). The organic layer was dried with anhydrous sodium sulfate, filtered and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography (eluent: ethyl acetate/petroleum ether=1/1) to afford methyl 4-formyl-N-methylpyrrole-2-carboxylate (11.77 g, 70.42 mmol, 98% yield) as a yellow solid. Mass spectrum (EI+, m/z): 168.2 [M+H]+. NMR hydrogen spectrum (400 MHz, DMSO-d6) δ 9.71 (s, 1H), 7.91 (d, J=1.8 Hz, 1H), 7.22 (d, J=1.8 Hz, 1H), 3.92 (s, 3H), 3.78 (s, 3H).NOESY experiments further confirmed the structure of the target compound.
References
[1] Patent: WO2018/89493, 2018, A1. Location in patent: Paragraph 00215
[2] Medicinal Chemistry Research, 1995, vol. 5, # 6, p. 426 - 430
METHYL 4-FORMYL-1-METHYL-1H-PYRROLE-2-CARBOXYLATE Preparation Products And Raw materials
Raw materials
Preparation Products
METHYL 4-FORMYL-1-METHYL-1H-PYRROLE-2-CARBOXYLATE Suppliers
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 86-027-67849912
- Fax
- 86-027-87531808
- sales@chemwish.com
- Country
- China
- ProdList
- 35896
- Advantage
- 56
- Tel
- +86 (0) 571 85 58 67 18
- Fax
- 0086-571-85864795
- Country
- China
- ProdList
- 18207
- Advantage
- 66
- Tel
- +86 (21) 6435-5022
- Country
- China
- ProdList
- 4267
- Advantage
- 65
- Tel
- 0512-65617459 18915409046
- Fax
- 0512-65617459
- sales@sibian-chem.com
- Country
- China
- ProdList
- 1922
- Advantage
- 55
- Tel
- 800-810-5118
- Fax
- +86-10-84193589
- cnchemical@thermofisher.com
- Country
- China
- ProdList
- 17770
- Advantage
- 75
- Tel
- 4009209199
- Fax
- 86-021-52271987
- sales@9dingchem.com
- Country
- China
- ProdList
- 22514
- Advantage
- 55
- Tel
- 0086-573-82585213
- Fax
- 0086-573-82585233
- bai@chimicalabs.com
- Country
- China
- ProdList
- 861
- Advantage
- 64
- Tel
- 13982188065
- Fax
- -
- 2983871989@qq.com
- Country
- China
- ProdList
- 49
- Advantage
- 55
- Tel
- 13817873692
- Fax
- 021-31329586
- mkt@boynerspharm.com
- Country
- China
- ProdList
- 1707
- Advantage
- 55
View Lastest Price from METHYL 4-FORMYL-1-METHYL-1H-PYRROLE-2-CARBOXYLATE manufacturers
- Product
- METHYL 4-FORMYL-1-METHYL-1H-PYRROLE-2-CARBOXYLATE 67858-47-3
- Price
- US $9.80/KG
- Min. Order
- 1g
- Purity
- ≥99%
- Supply Ability
- 100kg
- Release date
- 2020-01-09