3-BROMO-1-(TRIISOPROPYLSILYL)PYRROLE
- Product Name
- 3-BROMO-1-(TRIISOPROPYLSILYL)PYRROLE
- CAS No.
- 87630-36-2
- Chemical Name
- 3-BROMO-1-(TRIISOPROPYLSILYL)PYRROLE
- Synonyms
- 3-BROMO-1-(TRIISOPROPYLSILYL)-1H-PYRROLE;3-bromo-1-[tris(propan-2-yl)silyl]-1H-pyrrole;DK941;3-BroMo-1-(triisopropylsi...;Bromotriisopropylsilylpyrrole;3-BROMO-1-(TRIISOPROPYLSILYL)PYRROLE;3-Bromo-N-(triisopropylsilyl)pyrrole;1-(TRIISOPROPYLSILYL)-3-BROMO-PYRROLE;3-Bromo-1(triisopropysilyl)pyrrole ;1-(Triisopropylsilyl)-3-bromo-1H-pyrrole
- CBNumber
- CB4231491
- Molecular Formula
- C13H24BrNSi
- Formula Weight
- 302.33
- MOL File
- 87630-36-2.mol
3-BROMO-1-(TRIISOPROPYLSILYL)PYRROLE Property
- Boiling point:
- 100 °C(Press: 0.1 Torr)
- Density
- 1,16 g/cm3
- refractive index
- n20/D1.519
- Flash point:
- >110℃
- storage temp.
- Inert atmosphere,2-8°C
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- form
- Oil
- pka
- -5.67±0.70(Predicted)
- color
- Black
- InChI
- InChI=1S/C13H24BrNSi/c1-10(2)16(11(3)4,12(5)6)15-8-7-13(14)9-15/h7-12H,1-6H3
- InChIKey
- CNAUTMPRKBSDLH-UHFFFAOYSA-N
- SMILES
- N1([Si](C(C)C)(C(C)C)C(C)C)C=CC(Br)=C1
- CAS DataBase Reference
- 87630-36-2(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn
- Risk Statements
- 36/37/38-20/21/22
- Safety Statements
- 26-36/37/39-36/37
- WGK Germany
- 3
- HS Code
- 2933.99.9701
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B1899
- Product name
- 3-Bromo-1-(triisopropylsilyl)pyrrole
- Purity
- >95.0%(GC)
- Packaging
- 1g
- Price
- $66
- Updated
- 2025/07/31
- Product number
- B1899
- Product name
- 3-Bromo-1-(triisopropylsilyl)pyrrole
- Purity
- >95.0%(GC)
- Packaging
- 5g
- Price
- $217
- Updated
- 2025/07/31
- Product number
- B1899
- Product name
- 3-Bromo-1-(triisopropylsilyl)pyrrole
- Purity
- >95.0%(GC)
- Packaging
- 25g
- Price
- $980
- Updated
- 2025/07/31
- Product number
- B699075
- Product name
- 3-Bromo-1-(triisopropylsilyl)pyrrole
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- B699075
- Product name
- 3-Bromo-1-(triisopropylsilyl)pyrrole
- Packaging
- 250mg
- Price
- $50
- Updated
- 2021/12/16
3-BROMO-1-(TRIISOPROPYLSILYL)PYRROLE Chemical Properties,Usage,Production
Uses
3-Bromo-1-(triisopropylsilyl)pyrrole is a pyrrole analogue mainly used in the field of organic synthesis. It can be used to prepare other heterocyclic compounds such as 1-(triisopropylsilyl)pyrrole and 3-Butadienyl-1-tosylpyrroles.
Synthesis
87630-35-1
87630-36-2
General procedure for the synthesis of 3-bromo-1-(triisopropylmethylsilyl)pyrrole from 1-(triisopropylmethylsilyl)pyrrole: at -78 °C, N-bromosuccinimide (NBS, 3.25 g, 18.3 mmol) was slowly added to a 1-(triisopropylmethylsilyl)pyrrole (3.72 g, 16.6 mmol) solution of tetrahydrofuran (THF, 17 mL ) solution was maintained at temperature and stirred continuously for 5 hours. Upon completion of the reaction, hexane (15 mL) and pyridine (0.5 mL) were added to the mixture and stirring was continued for 5 minutes. Subsequently, the solvent was removed by distillation under reduced pressure to give the crude product. The crude product was purified by silica gel column chromatography (eluent: n-hexane/ethyl acetate=30:1) to finally obtain 3-bromo-1-(triisopropylmethylsilyl)pyrrole (4.67 g, 93% yield) as a colorless oil.
References
[1] Chemische Berichte, 1989, vol. 122, p. 169 - 174
[2] Tetrahedron, 2011, vol. 67, # 35, p. 6673 - 6678
[3] Journal of Organic Chemistry, 1984, vol. 49, # 17, p. 3239 - 3240
[4] Tetrahedron, 2004, vol. 60, # 34, p. 7141 - 7146
[5] Organic Letters, 2014, vol. 16, # 24, p. 6334 - 6337
3-BROMO-1-(TRIISOPROPYLSILYL)PYRROLE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-BROMO-1-(TRIISOPROPYLSILYL)PYRROLE manufacturers
- Product
- 3-BROMO-1-(TRIISOPROPYLSILYL)PYRROLE 87630-36-2
- Price
- US $6.68/KG
- Min. Order
- 1KG
- Purity
- 97%-99%
- Supply Ability
- 1kg-1000kg
- Release date
- 2020-01-10