L-Aspartic acid 4-benzyl ester
- Product Name
- L-Aspartic acid 4-benzyl ester
- CAS No.
- 2177-63-1
- Chemical Name
- L-Aspartic acid 4-benzyl ester
- Synonyms
- H-ASP(OBZL)-OH;L-Aspartic acid β-benzyl ester;Asp(OBz)-OH;H-Asp(OBn)-OH;H-L-Asp(Bzl)-OH;H-L-ASP(OBZL)-OH;H-ASP(OBZL)-OH 98%;B-BENZYL L-ASPARTATE;4-BENZYL L-ASPARTATE;á-benzyl l-aspartate
- CBNumber
- CB4232504
- Molecular Formula
- C11H13NO4
- Formula Weight
- 223.23
- MOL File
- 2177-63-1.mol
L-Aspartic acid 4-benzyl ester Property
- Melting point:
- ~225 °C (dec.)
- Boiling point:
- 413.1±45.0 °C(Predicted)
- Density
- 1.283±0.06 g/cm3(Predicted)
- refractive index
- 27 ° (C=1, 1mol/L HCl)
- storage temp.
- Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- pka
- 2.16±0.23(Predicted)
- form
- Powder
- color
- White
- Water Solubility
- Insoluble in water.
- BRN
- 1983183
- CAS DataBase Reference
- 2177-63-1(CAS DataBase Reference)
Safety
- Safety Statements
- 22-24/25
- WGK Germany
- 3
- HS Code
- 29242990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- B2129
- Product name
- L-Aspartic acid β-benzyl ester
- Packaging
- 25g
- Price
- $368
- Updated
- 2025/07/31
- Product number
- B3209
- Product name
- 4-Benzyl L-Aspartate
- Purity
- >98.0%(T)
- Packaging
- 5g
- Price
- $57
- Updated
- 2025/07/31
- Product number
- B3209
- Product name
- 4-Benzyl L-Aspartate
- Purity
- >98.0%(T)
- Packaging
- 25g
- Price
- $192
- Updated
- 2025/07/31
- Product number
- A788668
- Product name
- H-Asp(OBzl)-OH
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- FA47538
- Product name
- L-Aspartic acid b-benzyl ester
- Packaging
- 50g
- Price
- $60
- Updated
- 2021/12/16
L-Aspartic acid 4-benzyl ester Chemical Properties,Usage,Production
Chemical Properties
Crystalline
Uses
L-Aspartic acid β-benzyl ester is used in the synthesis of peptides with a 1,4-diazepine-2,5-dione ring structure and in development of block copolymers.
Definition
ChEBI: L-aspartic acid beta-benzyl ester is an aspartic acid derivative.
Synthesis
56-84-8
100-51-6
2177-63-1
100 mL of anhydrous ether was added to a 500 mL beaker and 20 mL of concentrated sulfuric acid was added slowly and dropwise while stirring and cooling to room temperature. Subsequently, 150 mL of benzyl alcohol was added and the ether was removed by stirring well. Under reduced pressure, 26 g of L-aspartic acid was added to the reaction flask in 5 batches. The reaction was stirred for 24 h at room temperature, after which 300 mL of 95% ethanol was added, and 80 mL of pyridine was slowly added dropwise through a dropping funnel with vigorous stirring while dropping. The reaction mixture was placed in a refrigerator overnight and the solid was collected by filtration. The solid was dissolved with 80% ethanol with stirring, heated and filtered. The filtrate was frozen for 8 hours, filtered again and finally lyophilized to obtain pure β-aspartic acid benzyl ester in 90% yield.
References
[1] Journal of Natural Products, 2017, vol. 80, # 7, p. 2136 - 2140
[2] Patent: CN107129501, 2017, A. Location in patent: Paragraph 0009; 0010; 0011
[3] Synthesis and Reactivity in Inorganic, Metal-Organic and Nano-Metal Chemistry, 2011, vol. 41, # 5, p. 459 - 464
[4] Patent: US2004/133033, 2004, A1. Location in patent: Page 4-5
[5] Chemistry - A European Journal, 2018, vol. 24, # 54, p. 14373 - 14377
L-Aspartic acid 4-benzyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
L-Aspartic acid 4-benzyl ester Suppliers
- Tel
- 800-4238616
- Fax
- +1-888-520-1075 / +1-503-283-1987
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- Country
- Americas
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- Advantage
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View Lastest Price from L-Aspartic acid 4-benzyl ester manufacturers
- Product
- H-Asp(OBzl)-OH 2177-63-1
- Price
- US $0.00/Kg/Drum
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 500kgs
- Release date
- 2021-09-26
- Product
- H-L-Asp(OBzl)-OH 2177-63-1
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1T+
- Release date
- 2024-03-12
- Product
- L-Aspartic acid 4-benzyl ester 2177-63-1
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1ton
- Release date
- 2022-10-13