SECOBARBITAL
- Product Name
- SECOBARBITAL
- CAS No.
- 76-73-3
- Chemical Name
- SECOBARBITAL
- Synonyms
- Evronal;Immenox;Seconal;somosal;Barbosec;Hypotrol;Imesonal;Trisomnin;Somatarax;Immenoctal
- CBNumber
- CB4238324
- Molecular Formula
- C12H18N2O3
- Formula Weight
- 238.28
- MOL File
- 76-73-3.mol
SECOBARBITAL Property
- Melting point:
- 98°C
- Boiling point:
- 380.88°C (rough estimate)
- Density
- 1.1343 (rough estimate)
- refractive index
- 1.4760 (estimate)
- Flash point:
- 11 °C
- storage temp.
- 2-8°C
- solubility
- Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly)
- pka
- 7.81±0.10(Predicted)
- Water Solubility
- 1.728g/L(24 ºC)
- EPA Substance Registry System
- 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-(1-methylbutyl)-5-(2-propen-1-yl)- (76-73-3)
Safety
- Hazard Codes
- F,T
- Risk Statements
- 11-23/24/25-39/23/24/25-36/37/38-25
- Safety Statements
- 36/37-45-26-16
- RIDADR
- UN 1230 3/PG 2
- WGK Germany
- 2
- RTECS
- CP9450000
- HazardClass
- 6.1(b)
- PackingGroup
- III
- HS Code
- 2933530000
- Hazardous Substances Data
- 76-73-3(Hazardous Substances Data)
- Toxicity
- A barbiturate sedative-hypnotic with a long half-life, the abuse of which can lead to tolerance and dependence. The oral LD50 in rats is 125 mg/kg.
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 1611004
- Product name
- Secobarbital
- Purity
- United States Pharmacopeia (USP) Reference Standard
- Packaging
- 200mg
- Price
- $506
- Updated
- 2024/03/01
- Product number
- S-002
- Product name
- Secobarbital solution
- Purity
- 1?mg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant?
- Packaging
- 1ML
- Price
- $23.8
- Updated
- 2022/05/15
- Product number
- 21707
- Product name
- Secobarbital (CRM)
- Packaging
- 1mg
- Price
- $20
- Updated
- 2023/06/20
- Product number
- 15791
- Product name
- Secobarbital
- Packaging
- 5mg
- Price
- $59
- Updated
- 2023/06/20
- Product number
- 15791
- Product name
- Secobarbital
- Packaging
- 1mg
- Price
- $20
- Updated
- 2023/06/20
SECOBARBITAL Chemical Properties,Usage,Production
Description
Secobarbital (CRM) (Item No. 21707) is a certified reference material categorized as a barbiturate. It extends intoxication and increases withdrawal effects in patients with a family history of alcoholism. Secobarbital is regulated as a Schedule II compound in the United States. Secobarbital (CRM) (Item No. 21707) is provided as a DEA exempt preparation. This product is intended for research and forensic applications.
Uses
Barbiturates are being widely used as antiepileptics, hypnotics, and anesthetics Controlled substance.
Definition
ChEBI: A member of the class of barbiturates that is barbituric acid in which the hydrogens at position 5 are substituted by prop-2-en-1-yl and pentan-2-yl groups.
brand name
Seconal(Lilly);Seconal sodium;Tuinal.
World Health Organization (WHO)
Secobarbital is a short to intermediate-acting barbiturate which is controlled under Schedule III of the 1971 Convention on Psychotropic Substances. See WHO comment for barbiturates. (Reference: (UNCPS3) United Nations Convention on Psychotropic Substances (III), , , 1971)
Purification Methods
It is purified by dissolving the sodium salt [309-43-3] in 10% HCl which precipitates the acid form that is extracted into Et2O. The extract is dried (Na2SO4) and evaporated. The residue is then purified by repeated crystallisation from CHCl3. [Buchet & Sandorfy J Phys Chem 88 3274 1984, Beilstein 24 III/IV 2013.]