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SECOBARBITAL

Product Name
SECOBARBITAL
CAS No.
76-73-3
Chemical Name
SECOBARBITAL
Synonyms
Evronal;Immenox;Seconal;somosal;Barbosec;Hypotrol;Imesonal;Trisomnin;Somatarax;Immenoctal
CBNumber
CB4238324
Molecular Formula
C12H18N2O3
Formula Weight
238.28
MOL File
76-73-3.mol
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SECOBARBITAL Property

Melting point:
98°C
Boiling point:
380.88°C (rough estimate)
Density 
1.1343 (rough estimate)
refractive index 
1.4760 (estimate)
Flash point:
11 °C
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly)
pka
7.81±0.10(Predicted)
Water Solubility 
1.728g/L(24 ºC)
EPA Substance Registry System
2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-(1-methylbutyl)-5-(2-propen-1-yl)- (76-73-3)
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Safety

Hazard Codes 
F,T
Risk Statements 
11-23/24/25-39/23/24/25-36/37/38-25
Safety Statements 
36/37-45-26-16
RIDADR 
UN 1230 3/PG 2
WGK Germany 
2
RTECS 
CP9450000
HazardClass 
6.1(b)
PackingGroup 
III
HS Code 
2933530000
Hazardous Substances Data
76-73-3(Hazardous Substances Data)
Toxicity
A barbiturate sedative-hypnotic with a long half-life, the abuse of which can lead to tolerance and dependence. The oral LD50 in rats is 125 mg/kg.
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
1611004
Product name
Secobarbital
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
200mg
Price
$506
Updated
2024/03/01
Sigma-Aldrich
Product number
S-002
Product name
Secobarbital solution
Purity
1?mg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant?
Packaging
1ML
Price
$23.8
Updated
2022/05/15
Cayman Chemical
Product number
21707
Product name
Secobarbital (CRM)
Packaging
1mg
Price
$20
Updated
2023/06/20
Cayman Chemical
Product number
15791
Product name
Secobarbital
Packaging
5mg
Price
$59
Updated
2023/06/20
Cayman Chemical
Product number
15791
Product name
Secobarbital
Packaging
1mg
Price
$20
Updated
2023/06/20
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SECOBARBITAL Chemical Properties,Usage,Production

Description

Secobarbital (CRM) (Item No. 21707) is a certified reference material categorized as a barbiturate. It extends intoxication and increases withdrawal effects in patients with a family history of alcoholism. Secobarbital is regulated as a Schedule II compound in the United States. Secobarbital (CRM) (Item No. 21707) is provided as a DEA exempt preparation. This product is intended for research and forensic applications.

Uses

Barbiturates are being widely used as antiepileptics, hypnotics, and anesthetics Controlled substance.

Definition

ChEBI: A member of the class of barbiturates that is barbituric acid in which the hydrogens at position 5 are substituted by prop-2-en-1-yl and pentan-2-yl groups.

brand name

Seconal(Lilly);Seconal sodium;Tuinal.

World Health Organization (WHO)

Secobarbital is a short to intermediate-acting barbiturate which is controlled under Schedule III of the 1971 Convention on Psychotropic Substances. See WHO comment for barbiturates. (Reference: (UNCPS3) United Nations Convention on Psychotropic Substances (III), , , 1971)

Purification Methods

It is purified by dissolving the sodium salt [309-43-3] in 10% HCl which precipitates the acid form that is extracted into Et2O. The extract is dried (Na2SO4) and evaporated. The residue is then purified by repeated crystallisation from CHCl3. [Buchet & Sandorfy J Phys Chem 88 3274 1984, Beilstein 24 III/IV 2013.]

SECOBARBITAL Preparation Products And Raw materials

Raw materials

Preparation Products

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SECOBARBITAL Suppliers

76-73-3, SECOBARBITALRelated Search:


  • SECOBARBITAL
  • QUINALBARBITONE
  • 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-(1-methylbutyl)-5-(2-propenyl)-
  • 2,4,6(1H,3H,5H)-Pyrimidinitrione, 5-(1-methylbutyl)-5-(2-propenyl)-
  • 5-Allyl-5-(1-methylbutyl)-2,4,6(1H,3H,5H)-pyrimidinetrione
  • 5-allyl-5-(1-methylbutyl)barbiturate
  • 5-allyl-5-(1-methylbutyl)-barbituricaci
  • 5-Allyl-5-(1-methylbutyl)malonylurea
  • 6(1h,3h,5h)-pyrimidinetrione,5-(1-methylbutyl)-5-(2-propenyl)-4
  • 6(1h,3h,5h)-pyrimidinitrione,5-(1-methylbutyl)-5-(2-propenyl)-4
  • Barbituric acid, 5-allyl-5-(1-methylbutyl)-
  • Barbosec
  • component of Hyptran
  • Evronal
  • Hypotrol
  • Imesonal
  • Immenoctal
  • Immenox
  • Meballymal
  • Quinalbarbital
  • quinobarbitone
  • Secobarbitone
  • Seconal
  • somosal
  • Trisomnin
  • 5-ALLYL-5-[1-METHYLBUTYL]BARBITURIC ACID
  • Secobarbital (CRM)
  • secobarbital free acid--dea schedule ii item
  • secobarbital methanol solution
  • SECOBARBITAL 98+%
  • secobarbital solution
  • 5-ALLYL-5-(1-METHYLBUTYL)BARBITURICACID(SECOBARBITAL)
  • (RS)-Secobarbital
  • 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-(1-methylbutyl)-5-(2-propenyl)- (9CI)
  • Barbituric acid, 5-allyl-5-(1-methylbutyl)- (8CI)
  • Somatarax
  • Lorazepam Solution, 100ppm
  • 5-Allyl-5-(1-methylbutyl)barbituric acid, Quinalbarbitone, Seconal
  • (-)-5-Allyl-5-[(S)-1-methylbutyl]-2,4,6(1H,3H,5H)-pyrimidinetrione
  • (-)-5-Allyl-5-[(S)-1-methylbutyl]barbituric acid
  • 5-(1-Methylbutyl)-5-(2-propenyl)-2,4,6(1H,3H,5H)-pyrimidinetrione
  • (+)-5-Allyl-5-[(R)-1-methylbutyl]-2,4,6(1H,3H,5H)-pyrimidinetrione
  • (+)-5-Allyl-5-[(R)-1-methylbutyl]barbituric acid
  • 5-pentan-2-yl-5-prop-2-enyl-1,3-diazinane-2,4,6-trione
  • Secobarbital CII (200 mg)
  • 5-(1-Methylbutyl)-5-(2-propen-1-yl)-
  • 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-(1-methylbutyl)-5-(2-propen-1-yl)-
  • SECOBARBITAL USP/EP/BP
  • Secobarbital [Controlled Substance
  • 76-73-3
  • Analytical Standards
  • Analytical Chromatography Product Catalog
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