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BARBITAL

Product Name
BARBITAL
CAS No.
57-44-3
Chemical Name
BARBITAL
Synonyms
VERONAL;BARBITONE;Deba;Barbitone acid;DIETHYLBARBITURIC ACID;5,5-diethyl-1,3-diazinane-2,4,6-trione;Malona;Uronal;Diemal;Malonal
CBNumber
CB7380141
Molecular Formula
C8H12N2O3
Formula Weight
184.19
MOL File
57-44-3.mol
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BARBITAL Property

Melting point:
188-192°C
Boiling point:
318.14°C (rough estimate)
Density 
1.2200
refractive index 
1.4200 (estimate)
Flash point:
11 °C
storage temp. 
2-8°C
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
7.43(at 25℃)
color 
Faintly bitter crystals from H2O; polymorphicforms; triagonal crystals, monoclinic prisms, monoclinicneedles, and triclinic cryst
Water Solubility 
7.149g/L(25 ºC)
Merck 
13,965
EPA Substance Registry System
5,5-Diethylbarbituric acid (57-44-3)
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Safety

Hazard Codes 
Xn,T,F
Risk Statements 
22-39/23/24/25-23/24/25-11-63-40-20
Safety Statements 
36-45-36/37-16-7
RIDADR 
UN 1230 3/PG 2
WGK Germany 
3
RTECS 
CQ3500000
Toxicity
LDLo orl-cat: 280 mg/kg PHREA7 19,472,39
DEA Controlled Substances
CSCN: 2145
CSA SCH: Schedule IV
NARC: No
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
B0300000
Product name
Barbital
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
B0300000
Price
$152
Updated
2024/03/01
Cayman Chemical
Product number
22854
Product name
Barbital (CRM)
Packaging
1mg
Price
$31
Updated
2023/06/20
Cayman Chemical
Product number
22012
Product name
Barbital
Packaging
5mg
Price
$59
Updated
2023/06/20
Cayman Chemical
Product number
22012
Product name
Barbital
Packaging
1mg
Price
$20
Updated
2023/06/20
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BARBITAL Chemical Properties,Usage,Production

Description

Barbital is an analytical reference material that is categorized as a barbiturate. It acts as an agonist at GABAA receptors to induce central nervous system depression. Formulations containing barbital have been used as a sedative to treat insomnia and seizures in human and veterinary medicine. Barbital is regulated as a Schedule IV compound in the United States. This product is intended for research and forensic applications.

Description

Barbital (CRM) (Item No. 22854) is a certified reference material categorized as a barbiturate. Barbital is regulated as a Schedule IV compound in the United States. Barbital (CRM) (Item No. 22854) is provided as a DEA exempt preparation. This product is intended for research and forensic applications.

Chemical Properties

White crystals or powder; bitter taste; odorless. Stable in air. Soluble in hot water, alcohol, ether, acetone, and ethyl acetate.

Uses

Prototype of the barbiturate hypnotics.

Definition

ChEBI: A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by two ethyl groups. Formerly used as a hypnotic (sleeping aid).

brand name

Dormileno;Escoderm;Hypnogene;Hypnox;Lidor;Megal;Plexonal;Somnytic tablets;Verinogen;Verodon;Veroletten;Verolitten;Veronigen.

World Health Organization (WHO)

Barbital is a long-acting barbiturate which is controlled under Schedule IV of the 1971 Convention on Psychotropic Substances. See WHO comment for barbiturates. (Reference: (UNCPS4) United Nations Convention on Psychotropic Substances (IV), , , 1971)

Safety Profile

Poison by ingestion, intravenous,intraperitoneal, and subcutaneous routes. Ingestion causespsychological effects in humans. Mutation data reported.When heated to decomposition it emits toxic fumes ofNOx. An hypnotic andsedative.

Purification Methods

Crystallise barbital from water or EtOH and dry it in a vacuum over P2O5. [Beilstein 24 III/IV 1901.]

BARBITAL Preparation Products And Raw materials

Raw materials

Preparation Products

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BARBITAL Suppliers

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