1,3-Dimethylbarbituric acid

Product Name: 1,3-Dimethylbarbituric acid
CAS No.: 769-42-6
Chemical Name: 1,3-Dimethylbarbituric acid
Synonyms: 1,3-DIMETHYLPYRIMIDINE-2,4,6(1H,3H,5H)-TRIONE;1,3-Dimethylbarbituric;1,3-DiMethyl-;N,N'-Dimethylbarbituric acid;1,3-DIMETHYL-2,4,6(1H,3H,5H)-PYRIMIDINETRIONE;2,4,6(1H,3H,5H)-Pyrimidinetrione, 1,3-dimethyl-;6(1H;AKOS B029702;Uradil impurity 19;1,3-Dimethylbarbitur
CBNumber: CB9121414
Molecular Formula: C6H8N2O3
Formula Weight: 156.14
MOL File: 769-42-6.mol

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1,3-Dimethylbarbituric acid Property

Melting point:: 121-123 °C (lit.) 121-123 °C
Boiling point:: 228.1±23.0 °C(Predicted)
Density: 1.322±0.06 g/cm3(Predicted)
bulk density: 500kg/m3
storage temp.: -20°C Freezer
solubility: hot water: soluble0.5g/10 mL, clear, colorless to faintly yellow
form: Crystalline Powder
pka: pK1:4.68(+1) (25°C)
color: White/cream/pale yellow
PH: 2.5 (20°C, 100g/L in H2O, slurry)
Water Solubility: Soluble in water.
BRN: 139810
InChI: 1S/C6H8N2O3/c1-7-4(9)3-5(10)8(2)6(7)11/h3H2,1-2H3
InChIKey: VVSASNKOFCZVES-UHFFFAOYSA-N
SMILES: CN1C(=O)CC(=O)N(C)C1=O
CAS DataBase Reference: 769-42-6(CAS DataBase Reference)
NIST Chemistry Reference: 1,3-Dimethylbarbituric acid(769-42-6)
EPA Substance Registry System: 2,4,6(1H,3H,5H)-Pyrimidinetrione, 1,3-dimethyl- (769-42-6)

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Safety

Hazard Codes: Xn
Risk Statements: 22-41
Safety Statements: 26-36/39
WGK Germany: 3
TSCA: TSCA listed
HS Code: 29339900
Storage Class: 11 - Combustible Solids
Hazard Classifications: Acute Tox. 4 Oral
Eye Dam. 1

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H318Causes serious eye damage

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 39565
Product name: 1,3-Dimethylbarbituric acid
Purity: ≥99.0% (T)
Packaging: 50g
Price: $97.6
Updated: 2026/03/19

Sigma-Aldrich

Product number: 39565
Product name: 1,3-Dimethylbarbituric acid
Purity: ≥99.0% (T)
Packaging: 250g
Price: $240
Updated: 2026/03/19

TRC

Product number: D463650
Product name: 1,3-Dimethylbarbituric acid
Packaging: 25g
Price: $2240
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0017293
Product name: 1,3-DIMETHYLBARBITURIC ACID
Purity: 95.00%
Packaging: 1G
Price: $750.75
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD128015
Product name: 1,3-Dimethyl-2,4,6(1H,3H,5H)-pyrimidinetrione
Packaging: 2Kg
Price: $400
Updated: 2021/12/16

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1,3-Dimethylbarbituric acid Chemical Properties,Usage,Production

Chemical Properties

Yellow or brownish powder

Uses

1,3-Dimethylbarbituric acid is used as a catalyst in the Knoevenagel condensation of a series of aromatic aldehydes. It is also used in the synthesis of 5-aryl-6-(alkyl- or aryl-amino)-1,3-dimethylfuro [2,3-d]pyrimidine derivatives and enantioselective synthesis of isochromene pyrimidinedione derivatives.

Uses

1,3-Dimethyl Barbituric Acid (Urapidil Impurity 4) is a derivative of Barbituric acid. All of the barbituric acid derivatives which have been reported to have pronounced hypnotic activity are disubstituted in the 5-position.

General Description

1,3-Dimethylbarbituric acid (1,3-Dimethyl-2,4,6(1H,3H,5H)-pyrimidinetrione) is an active methylene compound. It undergoes hollow Pd₆ water-soluble cage, [{(tmen)Pd}₆(timb)₄](NO₃)₁₂ (tmen= N,N,N′,N′-tetramethylethylenediamine, timb=1,3,5-tris(1-imidazolyl)benzene)-catalyzed Knoevenagel condensation reaction with pyrene-1-carboxaldehyde. It undergoes self-sorted Pd₇ molecular boat having an internal nanocavity (catalyst)-assisted Knoevenagel condensation reaction with various aromatic aldehydes. It has been synthesized by reacting 1,3-dimethylurea, malonic acid and acetic anhydride in acetic acid. It is widely used for the synthesis of various synthetic intermediates and heterocyclic compounds.

Purification Methods

Crystallise the acid from water and sublime it in a vacuum. Also purify it by dissolving 10g in 100mL of boiling CCl4/CHCl3 (8:2) (1g charcoal), filtering and cooling to 25o. Dry it in vacuo [Kohn et al. Anal Chem 58 3184 1986]. [Beilstein 24 III/IV 1875.]

1,3-Dimethylbarbituric acid Preparation Products And Raw materials

Raw materials

Preparation Products

6-[N-(2-Hydroxyethyl)amino]-1,3-dimethyl-2,4(1H,3H)-dione

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1,3-Dimethylbarbituric acid Suppliers

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View Lastest Price from 1,3-Dimethylbarbituric acid manufacturers

Hangzhou Lucky Biology Co., Ltd

Product: 1,3-Dimethylbarbituric acid 769-42-6
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99
Supply Ability: TONS
Release date: 2026-02-23

Chongqing Soarwin Technology Co., Ltd

Product: 1,3-Dimethylbarbituric acid 769-42-6
Price: US $0.00-0.00/Kg
Min. Order: 1Kg
Purity: 99.99%
Supply Ability: 20 tons
Release date: 2025-04-11

Jinan Finer Chemical Co., Ltd

Product: 1,3-Dimethylbarbituric acid 769-42-6
Price: US $22.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100mt
Release date: 2024-12-25

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Uradil impurity 19

1,3-DIMETHYLPYRIMIDINE-2,4,6(1H,3H,5H)-TRIONE

1,3-DIMETHYL-2,4,6(1H,3H,5H)-PYRIMIDINETRIONE

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769-42-6

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