1,3-Dimethylbarbituric acid
- Product Name
- 1,3-Dimethylbarbituric acid
- CAS No.
- 769-42-6
- Chemical Name
- 1,3-Dimethylbarbituric acid
- Synonyms
- 1,3-DIMETHYLPYRIMIDINE-2,4,6(1H,3H,5H)-TRIONE;1,3-DiMethyl-;1,3-Dimethylbarbituric;2,4,6(1H,3H,5H)-Pyrimidinetrione, 1,3-dimethyl-;6(1H;AKOS B029702;1,3-Dimethylbarbitur;Dimethylbarbituric acid;1,3-dimethylbarbiturates;1,3-DIMETHYLBARBITURIC ACID
- CBNumber
- CB9121414
- Molecular Formula
- C6H8N2O3
- Formula Weight
- 156.14
- MOL File
- 769-42-6.mol
1,3-Dimethylbarbituric acid Property
- Melting point:
- 121-123 °C (lit.) 121-123 °C
- Boiling point:
- 228.1±23.0 °C(Predicted)
- Density
- 1.322±0.06 g/cm3(Predicted)
- storage temp.
- -20°C Freezer
- solubility
- hot water: soluble0.5g/10 mL, clear, colorless to faintly yellow
- form
- Crystalline Powder
- pka
- pK1:4.68(+1) (25°C)
- color
- White/cream/pale yellow
- Water Solubility
- Soluble in water.
- BRN
- 139810
- CAS DataBase Reference
- 769-42-6(CAS DataBase Reference)
- NIST Chemistry Reference
- 1,3-Dimethylbarbituric acid(769-42-6)
- EPA Substance Registry System
- 2,4,6(1H,3H,5H)-Pyrimidinetrione, 1,3-dimethyl- (769-42-6)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H318Causes serious eye damage
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 39565
- Product name
- 1,3-Dimethylbarbituric acid
- Purity
- ≥99.0% (T)
- Packaging
- 50g
- Price
- $88.9
- Updated
- 2024/03/01
- Product number
- 39565
- Product name
- 1,3-Dimethylbarbituric acid
- Purity
- ≥99.0% (T)
- Packaging
- 250g
- Price
- $219
- Updated
- 2024/03/01
- Product number
- D463650
- Product name
- 1,3-Dimethylbarbituric acid
- Packaging
- 25g
- Price
- $2240
- Updated
- 2021/12/16
- Product number
- JK127134
- Product name
- 1,3-Dimethylbarbituric acid
- Purity
- 98%
- Packaging
- 500g
- Price
- $178
- Updated
- 2021/12/16
- Product number
- CHM0017293
- Product name
- 1,3-DIMETHYLBARBITURIC ACID
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $750.75
- Updated
- 2021/12/16
1,3-Dimethylbarbituric acid Chemical Properties,Usage,Production
Chemical Properties
Yellow or brownish powder
Uses
1,3-Dimethylbarbituric acid is used as a catalyst in the Knoevenagel condensation of a series of aromatic aldehydes. It is also used in the synthesis of 5-aryl-6-(alkyl- or aryl-amino)-1,3-dimethylfuro [2,3-d]pyrimidine derivatives and enantioselective synthesis of isochromene pyrimidinedione derivatives.
Uses
1,3-Dimethyl Barbituric Acid (Urapidil Impurity 4) is a derivative of Barbituric acid. All of the barbituric acid derivatives which have been reported to have pronounced hypnotic activity are disubstituted in the 5-position.
General Description
1,3-Dimethylbarbituric acid (1,3-Dimethyl-2,4,6(1H,3H,5H)-pyrimidinetrione) is an active methylene compound. It undergoes hollow Pd6 water-soluble cage, [{(tmen)Pd}6(timb)4](NO3)12 (tmen= N,N,N′,N′-tetramethylethylenediamine, timb=1,3,5-tris(1-imidazolyl)benzene)-catalyzed Knoevenagel condensation reaction with pyrene-1-carboxaldehyde. It undergoes self-sorted Pd7 molecular boat having an internal nanocavity (catalyst)-assisted Knoevenagel condensation reaction with various aromatic aldehydes. It has been synthesized by reacting 1,3-dimethylurea, malonic acid and acetic anhydride in acetic acid. It is widely used for the synthesis of various synthetic intermediates and heterocyclic compounds.
Purification Methods
Crystallise the acid from water and sublime it in a vacuum. Also purify it by dissolving 10g in 100mL of boiling CCl4/CHCl3 (8:2) (1g charcoal), filtering and cooling to 25o. Dry it in vacuo [Kohn et al. Anal Chem 58 3184 1986]. [Beilstein 24 III/IV 1875.]
1,3-Dimethylbarbituric acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1,3-Dimethylbarbituric acid manufacturers
- Product
- 1,3-Dimethylbarbituric acid 769-42-6
- Price
- US $0.00/Kg/Drum
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100mt/year
- Release date
- 2021-06-08
- Product
- 1,3-Dimethylbarbituric acid 769-42-6
- Price
- US $100.00-40.00/kg
- Min. Order
- 100kg
- Purity
- 99.99%
- Supply Ability
- 100Tons
- Release date
- 2023-03-17
- Product
- 1,3-Dimethylbarbituric acid 769-42-6
- Price
- US $70.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 1000000tons
- Release date
- 2023-11-03