6-O-TRIPHENYLMETHYL-ALPHA-D-GLUCOPYRANOSE
- Product Name
- 6-O-TRIPHENYLMETHYL-ALPHA-D-GLUCOPYRANOSE
- CAS No.
- 54325-28-9
- Chemical Name
- 6-O-TRIPHENYLMETHYL-ALPHA-D-GLUCOPYRANOSE
- Synonyms
- 6-O-Trityl-α-D-glucopyranose;6-O-TRITYL-ALPHA-D-GLUCOPYRANOSE;6-O-(Triphenylmethyl)-α-D-glucopyranose;6-O-TRIPHENYLMETHYL-ALPHA-D-GLUCOPYRANOSE;α-D-Glucopyranose, 6-O-(triphenylmethyl)-;(2S,3R,4S,5S,6R)-6-((Trityloxy)methyl)tetrahydro-2H-pyran-2,3,4,5-tetraol
- CBNumber
- CB42451905
- Molecular Formula
- C25H26O6
- Formula Weight
- 422.47
- MOL File
- 54325-28-9.mol
6-O-TRIPHENYLMETHYL-ALPHA-D-GLUCOPYRANOSE Property
- Boiling point:
- 595.6±50.0 °C(Predicted)
- Density
- 1.332±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- 12.09±0.70(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- CRB0005076
- Product name
- 6-O-TRIPHENYLMETHYL-ALPHA-D-GLUCOPYRANOSE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $503.93
- Updated
- 2021/12/16
- Product number
- A476635
- Product name
- (2S,3R,4S,5S,6R)-6-((Trityloxy)methyl)tetrahydro-2H-pyran-2,3,4,5-tetraol
- Purity
- 95+%
- Packaging
- 100mg
- Price
- $62
- Updated
- 2021/12/16
- Product number
- A476635
- Product name
- (2S,3R,4S,5S,6R)-6-((Trityloxy)methyl)tetrahydro-2H-pyran-2,3,4,5-tetraol
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $93
- Updated
- 2021/12/16
- Product number
- A476635
- Product name
- (2S,3R,4S,5S,6R)-6-((Trityloxy)methyl)tetrahydro-2H-pyran-2,3,4,5-tetraol
- Purity
- 95+%
- Packaging
- 1g
- Price
- $229
- Updated
- 2021/12/16
- Product number
- CD70000961
- Product name
- (2S,3R,4S,5S,6R)-6-((Trityloxy)methyl)tetrahydro-2H-pyran-2,3,4,5-tetraol
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $230
- Updated
- 2021/12/16
6-O-TRIPHENYLMETHYL-ALPHA-D-GLUCOPYRANOSE Chemical Properties,Usage,Production
Synthesis
50-99-7
76-83-5
54325-28-9
The general procedure for the synthesis of (2S,3R,4S,5S,6R)-6-((triphenylmethoxy)methyl)tetrahydro-2H-pyran-2,3,4,5-tetraol from D-anhydrous glucose and triphenylmethyl chloride was as follows: D-anhydrous glucose (5 g; 0.0277 mol) was suspended in pyridine (50 mL), followed by addition of triphenylmethyl chloride. The reaction mixture was stirred at 80 °C for about 4 hours. The progress of the reaction was monitored by thin layer chromatography (TLC) using dichloromethane: methanol (85:15) as the unfolding agent. Upon completion of the reaction, the reaction was quenched with water (100 mL) and extracted with dichloromethane (150 mL x 2). The organic layers were combined, washed with saturated aqueous sodium bicarbonate and dried over anhydrous sodium sulfate. The solvent was subsequently removed using a rotary evaporator. The target product (2S,3R,4S,5S,6R)-6-((triphenylmethoxy)methyl)tetrahydro-2H-pyran-2,3,4,5-tetraol (10.3 g; 88% yield) was finally obtained by milling the crude product with a hexane:ether mixture (100 mL) to remove residual triphthaloyl chloride and pyridine. The structure of the product was confirmed by LC-MS and the molecular ion peak (M+) was observed to be 446 amu.
References
[1] Patent: WO2007/54977, 2007, A2. Location in patent: Page/Page column 21
[2] Patent: KR101595939, 2016, B1. Location in patent: Paragraph 0102-0103
6-O-TRIPHENYLMETHYL-ALPHA-D-GLUCOPYRANOSE Preparation Products And Raw materials
Raw materials
Preparation Products
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