1-(BENZYLOXY)-4-BROMO-2-METHOXYBENZENE
- Product Name
- 1-(BENZYLOXY)-4-BROMO-2-METHOXYBENZENE
- CAS No.
- 63057-72-7
- Chemical Name
- 1-(BENZYLOXY)-4-BROMO-2-METHOXYBENZENE
- Synonyms
- 2-(Benzyloxy)-5-bromoanisole;4-Bromo-2-methoxy-1-phenylmethoxybenzene;Benzene, 4-bromo-2-methoxy-1-(phenylmethoxy)-
- CBNumber
- CB42456692
- Molecular Formula
- C14H13BrO2
- Formula Weight
- 293.16
- MOL File
- 63057-72-7.mol
1-(BENZYLOXY)-4-BROMO-2-METHOXYBENZENE Property
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- form
- Solid
- color
- White to Off-White
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation
H410Very toxic to aquatic life with long lasting effects
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P391Collect spillage. Hazardous to the aquatic environment
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- S813834
- Product name
- 1-(BENZYLOXY)-4-BROMO-2-METHOXYBENZENE
- Purity
- Aldrich<sup>CPR</sup>
- Packaging
- 1 unit
- Price
- $30.7
- Updated
- 2025/07/31
- Product number
- S813834
- Product name
- 1-(BENZYLOXY)-4-BROMO-2-METHOXYBENZENE
- Purity
- Aldrich
- Packaging
- 5mg
- Price
- $29.8
- Updated
- 2024/03/01
- Product number
- B291493
- Product name
- 1-(Benzyloxy)-4-bromo-2-methoxybenzene
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- V6997
- Product name
- 1-(Benzyloxy)-4-bromo-2-methoxybenzene
- Packaging
- 1g
- Price
- $103
- Updated
- 2021/12/16
- Product number
- HCH0109876
- Product name
- 1-(BENZYLOXY)-4-BROMO-2-METHOXYBENZENE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $503.25
- Updated
- 2021/12/16
1-(BENZYLOXY)-4-BROMO-2-METHOXYBENZENE Chemical Properties,Usage,Production
Synthesis
7368-78-7
100-39-0
63057-72-7
Step 1: Synthesis of 1-(benzyloxy)-4-bromo-2-methoxybenzene (2). Potassium carbonate (K2CO3, 30.5 g, 221 mmol) and benzyl bromide (18.9 g, 171 mmol) were added to a solution of N,N-dimethylformamide (DMF, 150 mL) containing 4-bromo-2-methoxyphenol (15 g, 73.8 mmol). The reaction mixture was stirred at 100 °C for 2 hours. Upon completion of the reaction, the reaction was quenched by the addition of water and the organic layer was extracted with ethyl acetate (EtOAc). The organic phases were combined and concentrated. The crude product was purified by column chromatography to afford the target compound 2 (17.6 g, 86% yield).
References
[1] Patent: US2005/43300, 2005, A1. Location in patent: Page/Page column 39
[2] Bioorganic and Medicinal Chemistry Letters, 2015, vol. 25, # 14, p. 2793 - 2799
[3] Journal of Organic Chemistry, 2002, vol. 67, # 10, p. 3425 - 3436
[4] Patent: WO2018/64557, 2018, A1. Location in patent: Paragraph 0444; 0445; 0446; 0447
[5] Patent: US2006/264473, 2006, A1. Location in patent: Page/Page column 5
1-(BENZYLOXY)-4-BROMO-2-METHOXYBENZENE Preparation Products And Raw materials
Raw materials
Preparation Products
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