ChemicalBook > CAS DataBase List > Pyrrolidine, 2-[diphenyl[(trimethylsilyl)oxy]methyl]-, (2R)-

Pyrrolidine, 2-[diphenyl[(trimethylsilyl)oxy]methyl]-, (2R)-

Product Name
Pyrrolidine, 2-[diphenyl[(trimethylsilyl)oxy]methyl]-, (2R)-
CAS No.
943757-71-9
Chemical Name
Pyrrolidine, 2-[diphenyl[(trimethylsilyl)oxy]methyl]-, (2R)-
Synonyms
(R)-Hayashi-Jorgensen Catalyst;R-Diphenylprolinol trimethyl silyl ether;α,α-Diphenyl-D-prolinol Trimethylsilyl Ether;(diphenyl(trimethylsilyloxy)methyl)pyrrolidine;(R)-Diphenylprolinol Trimethyl Silyl Ether,99%e.e.;alpha,alpha-Diphenyl-D-prolinol Trimethylsilyl Ether;(R)-2-[Diphenyl(trimethylsilanyloxy)methyl]pyrrolidine;(2R)-2-[Diphenyl[(trimethylsilyl)oxy]methyl]pyrrolidine;(R)-Diphenylprolinol trimethyl silyl ether, 95% (99% ee);[diphenyl-[(2R)-pyrrolidin-2-yl]methoxy]-trimethylsilane
CBNumber
CB42473763
Molecular Formula
C20H27NOSi
Formula Weight
325.52
MOL File
943757-71-9.mol
More
Less

Pyrrolidine, 2-[diphenyl[(trimethylsilyl)oxy]methyl]-, (2R)- Property

Boiling point:
412.7±35.0 °C(Predicted)
Density 
1.021
refractive index 
n20/D1.5509
Flash point:
>110℃
storage temp. 
2-8°C
pka
10.01±0.10(Predicted)
form 
clear liquid
color 
Light orange to Yellow to Green
optical activity
[α]22/D +52±5°, c = 1 in chloroform
InChI
InChI=1S/C20H27NOSi/c1-23(2,3)22-20(19-15-10-16-21-19,17-11-6-4-7-12-17)18-13-8-5-9-14-18/h4-9,11-14,19,21H,10,15-16H2,1-3H3/t19-/m1/s1
InChIKey
RSUHWMSTWSSNOW-LJQANCHMSA-N
SMILES
N1CCC[C@@H]1C(C1=CC=CC=C1)(C1=CC=CC=C1)O[Si](C)(C)C
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26
WGK Germany 
3
HS Code 
2933.99.8290
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
677191
Product name
(R)-(+)-α,α-Diphenyl-2-pyrrolidinemethanol trimethylsilyl ether
Purity
96%
Packaging
1g
Price
$77
Updated
2025/07/31
Sigma-Aldrich
Product number
677191
Product name
(R)-(+)-α,α-Diphenyl-2-pyrrolidinemethanol trimethylsilyl ether
Purity
96%
Packaging
5g
Price
$83.7
Updated
2025/07/31
TCI Chemical
Product number
D3867
Product name
(R)-(+)-α,α-Diphenyl-2-pyrrolidinemethanol Trimethylsilyl Ether
Purity
>98.0%(GC)(T)
Packaging
1g
Price
$337
Updated
2025/07/31
TCI Chemical
Product number
D3867
Product name
(R)-(+)-α,α-Diphenyl-2-pyrrolidinemethanol Trimethylsilyl Ether
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$1060
Updated
2025/07/31
Strem Chemicals
Product number
07-7234
Product name
(R)-Diphenylprolinol trimethyl silyl ether, 95% (99% ee)
Packaging
1g
Price
$108
Updated
2024/03/01
More
Less

Pyrrolidine, 2-[diphenyl[(trimethylsilyl)oxy]methyl]-, (2R)- Chemical Properties,Usage,Production

Uses

(R)-(+)-α,α-Diphenyl-2-pyrrolidinemethanol trimethylsilyl ether can be used as a catalyst to synthesize:

  • Glycofused tricyclic derivatives, which are used in the development of amyloid β-peptide diagnostic tools.
  • Cyclohexene carbaldehyde derivatives by reacting benzoylnitromethane with aliphatic enals.

General Description

(R)-(+)-α,α-Diphenyl-2-pyrrolidinemethanol trimethylsilyl ether is a diarylprolinol silyl ether organocatalyst.

Pyrrolidine, 2-[diphenyl[(trimethylsilyl)oxy]methyl]-, (2R)- Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Pyrrolidine, 2-[diphenyl[(trimethylsilyl)oxy]methyl]-, (2R)- Suppliers

Americas 1 CHINA 82 Europe 1 India 4 Japan 1 United Kingdom 1 United States 11 Global 101
Tianjin Derchemist Science & Technology Co., Ltd.
Tel
22-58627059 13920586291
Fax
022-58620305
Email
zdcomcon@126.com
Country
China
ProdList
3829
Advantage
50
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Country
China
ProdList
18207
Advantage
66
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9310
Advantage
66
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9883
Advantage
59
Daicel Chiral Technologies (China)CO.,LTD
Tel
021-50460086-9 15921403865
Fax
+86-21-50462321
Email
han_yajun@dctc.daicel.com
Country
China
ProdList
7471
Advantage
65
Shanghai Sunway Pharmaceutical Technology Co., Ltd
Tel
18270980682
Fax
021 51613951
Email
mlcheng@sunwaypharm.cn
Country
China
ProdList
8669
Advantage
57
Shanghai Holy Biohemdeviser Co., Ltd
Tel
021-61551100
Fax
021-61551100
Country
China
ProdList
444
Advantage
57
Sci General Material & Chemical Ltd
Tel
021-58388037;21-58388037 13472507714
Email
35177634@qq.com;1589045147@qq.com
Country
China
ProdList
803
Advantage
55
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9510
Advantage
58
SynAsst Chemical.
Tel
021-60343070
Fax
021-35122006
Country
China
ProdList
12740
Advantage
55
Shanghai Raise Chemical Technology Co.,Ltd
Tel
+86-021-50935922
Fax
+86-021-33847795
Country
China
ProdList
7865
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
Shanghai Xingui Biotechnology Co., Ltd.
Tel
15121041756
Email
xingui2022@126.com
Country
China
ProdList
9986
Advantage
58
Hangzhou J&H Chemical Co., Ltd.
Tel
0571-87396432
Fax
0571-87396431
Email
sales@jhechem.com
Country
China
ProdList
14912
Advantage
59
Chengdu RunZeBenTu Chemical Co., Ltd
Tel
13096311329 028-88469284 616445927
Fax
028-88469284
Email
616445927@qq.com
Country
China
ProdList
2874
Advantage
50
Cool Pharm, Ltd
Tel
021-60455363 18019463053
Fax
50966098
Email
sales@coolpharm.com
Country
China
ProdList
12346
Advantage
58
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51395
Advantage
80
Infinity SCI
Tel
400-106-2016 17800804092
Email
admin@infsci.com
Country
China
ProdList
553
Advantage
55
Shanghai Chiral bio-compound co., Ltd.
Tel
021-5068 3667/17749785980/1029026415; 17749785980
Fax
021-50683667
Email
1029026415@qq.com
Country
China
ProdList
3397
Advantage
58
Chengdu RunZeBenTu Chemical Co., Ltd
Tel
028-88469284 18000562381
Email
rzbtsj@163.com
Country
China
ProdList
9951
Advantage
56
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
LaaJoo
Tel
021-60702684 18516024827
Email
huang.jiayi@sinocompound.com
Country
China
ProdList
2280
Advantage
58
Greenherbs Science and Technology Development Co., Ltd.
Tel
010-61136123
Fax
+86 (10) 8857-9127
Email
pub02@greenherbs.com.cn
Country
China
ProdList
4049
Advantage
58
Capot Chemical Co.,Ltd.
Tel
+86-（0）57185586718; +8613336195806
Fax
+86-571-85864795
Email
sales@capot.com
Country
China
ProdList
29735
Advantage
60
Aikon International Limited
Tel
025-58859352 18068836627
Fax
(5)02557626880
Email
dt3@aikonchem.com
Country
China
ProdList
15493
Advantage
58
Wuhan FengyaoTonghui Chemical Products Co., Ltd.
Tel
027-87466105 15377573527
Email
2678564200@qq.com
Country
China
ProdList
17987
Advantage
58
Shanghai Haohong Pharmaceutical Co., Ltd.
Tel
400-8210725 400821072
Fax
021-58955996
Email
malulu@leyan.com
Country
China
ProdList
25000
Advantage
58
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400-6387771-6039 18920764717
Email
sales@heowns.com
Country
China
ProdList
23771
Advantage
60
Shanghai Anyinuo Biomedical Technology Co., Ltd.
Tel
021-34625901 18018851262;
Email
420970979@qq.com
Country
China
ProdList
5894
Advantage
58
Shanghai Jizhi Biochemical Technology Co. Ltd.
Tel
4009004166/18616739031 18616739031
Email
3007523370@qq.com
Country
China
ProdList
52687
Advantage
58
Guangdong wengjiang Chemical Reagent Co., Ltd.
Tel
0751-2815688 13927872512
Fax
0751-8963795
Email
3007421951@qq.com
Country
China
ProdList
9939
Advantage
58
TCI Chemicals
Tel
021-67121386, 800-988-0390
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
5391
Advantage
58
Labnetwork lnc.
Tel
+86-27-50766799 +8618062016861
Email
contact@labnetwork.com
Country
China
ProdList
19987
Advantage
58
Dayang Chem (Hangzhou) Co.,Ltd.
Tel
+86-0571-88938639 +8617705817739
Fax
+86-571-88938652，+86-571- 88492614
Email
info@dycnchem.com
Country
China
ProdList
52846
Advantage
58
Chongqing Chemdad Co., Ltd
Tel
+86-023-6139-8061 +86-86-13650506873
Email
sales@chemdad.com
Country
China
ProdList
39927
Advantage
58
CONIER CHEM AND PHARMA LIMITED
Tel
+8618523575427
Email
sales@conier.com
Country
China
ProdList
49975
Advantage
58
Shanghai Kaiwei Chemical Technology Co., Ltd.
Tel
021-58461859 15821823057
Email
service@aiviche.com
Country
China
ProdList
49312
Advantage
58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd
Tel
+8613580539051
Email
joe@yuhengpharm.com
Country
CHINA
ProdList
21142
Advantage
58
Jiaxing Hengrui Biotechnology Co. LTD
Tel
0573-0573-82672231 13757365595
Fax
QQ：715584339
Email
regen_chemical1@163.com
Country
China
ProdList
4839
Advantage
58
Henan Weitesi Chemical Technology Co. LTD
Tel
0371-0371-55135753 18003832934
Fax
QQ：2853979818
Email
2853979818@qq.com
Country
China
ProdList
9991
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing@energy-chemical.com
Country
China
ProdList
44918
Advantage
58
Bide Pharmatech Ltd.
Tel
400-6005915
Email
sales@picasso-e.com
Country
China
ProdList
39653
Advantage
58
Shanghai Aobo Pharmtech, Inc., Ltd.
Tel
021-51320499; 13564560425
Email
wywu@syncores.net
Country
China
ProdList
481
Advantage
58
Zhengzhou Hong Sheng Pharmaceutical Technology Co. Ltd.
Tel
0371-55695890 15637198702
Email
1677336983@qq.com
Country
China
ProdList
13191
Advantage
58
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
18621169109
Email
market03@meryer.com
Country
China
ProdList
27987
Advantage
58
Shanghai Yingxin laboratory equipment Co., Ltd
Tel
021-021-59178156 15300768757
Email
359382369@qq.com
Country
China
ProdList
10674
Advantage
58
Shaanxi Didu New Material Co., Ltd
Tel
029-81145920 17391631969
Email
1046@dideu.com
Country
China
ProdList
9996
Advantage
58
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 17801761073
Email
Gsiyu@solarbio.com
Country
China
ProdList
50751
Advantage
58
More
Less

View Lastest Price from Pyrrolidine, 2-[diphenyl[(trimethylsilyl)oxy]methyl]-, (2R)- manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
(R)-(+)-α,α-Diphenyl-2-pyrrolidinemethanol trimethylsilyl ether 943757-71-9
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27
Career Henan Chemical Co
Product
(R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine 943757-71-9
Price
US $1.00/KG
Min. Order
1KG
Purity
95%
Supply Ability
500KG
Release date
2018-08-19

943757-71-9, Pyrrolidine, 2-[diphenyl[(trimethylsilyl)oxy]methyl]-, (2R)-Related Search:

R-2-[diphenyl[(triethylsilyl)oxy]Methyl]-Pyrrolidine (R)-(+)-a,a-Diphenyl-2-pyrrolidinemethanol (S)-(-)-ALPHA,ALPHA-DIPHENYL-2-PYRROLIDINYL METHYLTMS ETHER

  • Pyrrolidine, 2-[diphenyl[(trimethylsilyl)oxy]methyl]-, (2R)-
  • (diphenyl(trimethylsilyloxy)methyl)pyrrolidine
  • R-Diphenylprolinol trimethyl silyl ether
  • (2R)-2-[Diphenyl[(trimethylsilyl)oxy]methyl]pyrrolidine
  • (R)-(+)-a,a-Diphenyl-2-pyrrolidineMethanol TriMethylsilyl Ether
  • (R)-(+)-alpha,alpha-Diphenyl-2-pyrrolidineMethanol triMethylsilyl ether 96%
  • (R)-(+)-α,α-Diphenyl-2-pyrrolidineMethanol triMethylsilyl ether 96%
  • (R)-2-[Diphenyl(trimethylsilanyloxy)methyl]pyrrolidine
  • (R)-Diphenylprolinol Trimethyl Silyl Ether,99%e.e.
  • (R)-(+)-alpha,alpha-Diphenyl-2-pyrrolidinemethanol Trimethylsilyl Ether
  • (R)-Diphenylprolinol trimethyl silyl ether, 95% (99% ee)
  • (R)-(+)-alpha,alpha-Diphenyl-2-pyrrolidinemethanol trimethylsilyl ether solution
  • α,α-Diphenyl-D-prolinol Trimethylsilyl Ether
  • (R)-Hayashi-Jorgensen Catalyst
  • alpha,alpha-Diphenyl-D-prolinol Trimethylsilyl Ether
  • (R)-(+)-α,α-Diphenyl-2-pyrrolidinemethanol trimethylsilyl ether
  • [diphenyl-[(2R)-pyrrolidin-2-yl]methoxy]-trimethylsilane
  • (R)-2-(diphenyl(trimethylsilyloxy)methyl)pyrrolidine methyl)pyrrilidine
  • (<i>R</i>)-(+)-α,α-Diphenyl-2-pyrrolidinemethanol trimethylsilyl ether
  • (R)-2-(DIPHENYL((TRIMETHYLSILYL)OXY)METHYL)PYRROLIDINE 95%
  • 943757-71-9