ChemicalBook > CAS DataBase List > (+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol

(+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol

Product Name
(+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol
CAS No.
106083-71-0
Chemical Name
(+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol
Synonyms
GW 353162;GW-353162A;BW-306U;Bupropion Morpholinol IMpurity;SS-hydroxybupropion hydrochloride;Bupropion Morpholinol (2S,3S)-Isomer;(2S,3S)-Hydroxybupropion hydrochloride;Bupropion Morpholinol IMpurity (HCl Salt);(2S,3S)-Hydroxybupropion hydrochloride >=98% (HPLC);(+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol;(+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol
CBNumber
CB42502638
Molecular Formula
C13H19Cl2NO2
Formula Weight
292.2
MOL File
106083-71-0.mol
More
Less

(+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol Property

storage temp. 
-20°C
solubility 
DMSO: ≥12mg/mL
form 
powder
color 
white to tan
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36
Safety Statements 
26
WGK Germany 
3
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
H3167
Product name
(2S,3S)-Hydroxybupropion hydrochloride
Purity
≥98% (HPLC)
Packaging
5mg
Price
$143
Updated
2024/03/01
Sigma-Aldrich
Product number
H3167
Product name
(2S,3S)-Hydroxybupropion hydrochloride
Purity
≥98% (HPLC)
Packaging
25mg
Price
$592
Updated
2024/03/01
American Custom Chemicals Corporation
Product number
API0004715
Product name
GW-353162A
Purity
95.00%
Packaging
25MG
Price
$1029.63
Updated
2021/12/16
ChemScene
Product number
CS-3815
Product name
Radafaxine(hydrochloride)
Purity
99.88%
Packaging
10mg
Price
$192
Updated
2021/12/16
ChemScene
Product number
CS-3815
Product name
Radafaxine(hydrochloride)
Purity
99.88%
Packaging
5mg
Price
$102
Updated
2021/12/16
More
Less

(+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol Chemical Properties,Usage,Production

Uses

Antidepressant; antianxiety.

General Description

(2S,3S)-hydroxybupropion is a major metabolite of bupropion.

Biochem/physiol Actions

(2S,3S)-hydroxybupropion is a dopamine transporter (DAT) and norepinephrine transporter (NET) transporters inhibitor and nicotinic acetylcholine receptor (nAChR) family modulator. Hydroxybupropions were reported to contribute to antidepressant and perhaps smoking cessation activities. Both (2S,3S) and (2R,3R) metabolites reverse affective and somatic withdrawal signs in nicotine-dependent mice, but (2S,3S)-hydroxybupropion is more potent. (2S,3S)-hydroxybupropion significantly decreases the development of nicotine reward in mice.

(+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

(+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol Suppliers

China 45 India 1 United States 8 Global 54
SynZeal Research Pvt Ltd
Tel
--
Fax
--
Email
standards@synzeal.com
Country
India
ProdList
6514
Advantage
58

106083-71-0, (+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-olRelated Search:

Bupropion 2-(TERT-BUTYLAMINO)PROPIOPHENONE HYDROCHLORIDE 2-(tert-ButylaMino)-3',5'-chloropropiophenone hydrochloride 1-(3-Chlorophenyl)-2-hydroxy-1-propanone Bupropion Hydrochloride Bupropion Hydrochloride Related Compound B (15 mg) (2-(tert-butylamino)-3'-bromopropiophenone hydrochloride) 2-(tert-ButylaMino)-3',4'-chloropropiophenone hydrochloride Bupropion Hydrochloride Related Compound A (15 mg) (2-(tert-butylamino)-4'-chloropropiophenone hydrochloride) 2-(tert-ButylaMino)-2'-chloropropiophenone Hydrochloride (R,R)-Hydroxy Bupropion

  • (+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethyl-2-morpholinol hydrochloride
  • (2S,3S)-2-(3-Chlorophenyl)-3,5,5-trimethyl-2-morpholinol hydrochloride
  • (2S,3S)-Hydroxybupropion hydrochloride
  • GW 353162
  • SS-hydroxybupropion hydrochloride
  • (+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol
  • Bupropion Morpholinol (2S,3S)-Isomer
  • Bupropion Morpholinol IMpurity
  • Bupropion Morpholinol IMpurity (HCl Salt)
  • GW-353162A;BW-306U
  • (2S,3S)-Hydroxybupropion hydrochloride >=98% (HPLC)
  • (+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol
  • 106083-71-0