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rac Lafutidine

Product Name
rac Lafutidine
CAS No.
206449-93-6
Chemical Name
rac Lafutidine
Synonyms
(Z)-FRG-8813;(Z)-Lafutidine;rac Lafutidine
CBNumber
CB42512282
Molecular Formula
C22H29N3O4S
Formula Weight
431.55
MOL File
206449-93-6.mol
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rac Lafutidine Property

Melting point:
94-99°C
Boiling point:
704.2±60.0 °C(Predicted)
Density 
1.252
storage temp. 
Amber Vial, -20°C Freezer
solubility 
Chloroform (Slightly), Dichloromethane (Slightly), DMSO (Slightly)
form 
Solid
pka
13.13±0.46(Predicted)
color 
White to Pale Yellow
Stability:
Light Sensitive
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
L168500
Product name
racLafutidine
Packaging
25mg
Price
$295
Updated
2021/12/16
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rac Lafutidine Chemical Properties,Usage,Production

Chemical Properties

rac Lafutidine is Off-White Solid

Uses

rac Lafutidine is a second generation histamine H2-receptor antagonist. Lafutidine is used as an antiulcerative.

Uses

Second generation histamine H2-receptor antagonist. Antiulcerative.

Definition

ChEBI: Lafutidine is an organic molecular entity.

in vivo

(Z)-Lafutidine (Compound 16) stimulates mucin biosynthesis in rat gastric mucosa and this effect not directly due to histamine H2 receptor antagonism[1].

Animal Model:Eight- to nine-week-old male C57BL/6 mice weighing 20-24g[1]
Dosage:3-30 mg/kg
Administration:P.o; twice for 6 days (5-FU: 50 mg/kg; i.p.;once daily)
Result:Reduced the severity of diarrhea during 5-FU treatment,in a mostly dose-dependent manner, and a significant effect was observed at a dose of 30 mg/kg.

rac Lafutidine Preparation Products And Raw materials

Raw materials

Preparation Products

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rac Lafutidine Suppliers

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206449-93-6, rac LafutidineRelated Search:


  • rac Lafutidine
  • (Z)-Lafutidine
  • (Z)-FRG-8813
  • 206449-93-6
  • C22H19D10N3O4S
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Sulfur & Selenium Compounds