ChemicalBook > CAS DataBase List > rac Lafutidine

rac Lafutidine

Product Name
rac Lafutidine
CAS No.
206449-93-6
Chemical Name
rac Lafutidine
Synonyms
(Z)-FRG-8813;(Z)-Lafutidine;rac Lafutidine
CBNumber
CB42512282
Molecular Formula
C22H29N3O4S
Formula Weight
431.55
MOL File
206449-93-6.mol
More
Less

rac Lafutidine Property

Melting point:
94-99°C
Boiling point:
704.2±60.0 °C(Predicted)
Density 
1.252
storage temp. 
Amber Vial, -20°C Freezer
solubility 
Chloroform (Slightly), Dichloromethane (Slightly), DMSO (Slightly)
form 
Solid
pka
13.13±0.46(Predicted)
color 
White to Pale Yellow
Stability:
Light Sensitive
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

TRC
Product number
L168500
Product name
racLafutidine
Packaging
25mg
Price
$295
Updated
2021/12/16
More
Less

rac Lafutidine Chemical Properties,Usage,Production

Chemical Properties

rac Lafutidine is Off-White Solid

Uses

rac Lafutidine is a second generation histamine H2-receptor antagonist. Lafutidine is used as an antiulcerative.

Uses

Second generation histamine H2-receptor antagonist. Antiulcerative.

Definition

ChEBI: Lafutidine is an organic molecular entity.

in vivo

(Z)-Lafutidine (Compound 16) stimulates mucin biosynthesis in rat gastric mucosa and this effect not directly due to histamine H2 receptor antagonism[1].

Animal Model:Eight- to nine-week-old male C57BL/6 mice weighing 20-24g[1]
Dosage:3-30 mg/kg
Administration:P.o; twice for 6 days (5-FU: 50 mg/kg; i.p.;once daily)
Result:Reduced the severity of diarrhea during 5-FU treatment,in a mostly dose-dependent manner, and a significant effect was observed at a dose of 30 mg/kg.

rac Lafutidine Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

rac Lafutidine Suppliers

Clearsynth Labs Limited
Tel
+91-22-26355700
Fax
+91-22-26355701
Email
info@clearsynth.com
Country
India
ProdList
9679
Advantage
58

206449-93-6, rac LafutidineRelated Search:


  • rac Lafutidine
  • (Z)-Lafutidine
  • (Z)-FRG-8813
  • 206449-93-6
  • C22H19D10N3O4S
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Sulfur & Selenium Compounds