8-bromoimidazo[1,2-a]pyridine-2-carboxylic acid
- Product Name
- 8-bromoimidazo[1,2-a]pyridine-2-carboxylic acid
- CAS No.
- 1026201-45-5
- Chemical Name
- 8-bromoimidazo[1,2-a]pyridine-2-carboxylic acid
- Synonyms
- 8-bromoimidazo[1,2-a]pyridine-2-carboxylic acid;8-BroMoH-iMidazo[1,2-a]pyridine-2-carboxylic acid;Imidazo[1,2-a]pyridine-2-carboxylic acid, 8-bromo-;8-Bromo-1,8a-dihydro-imidazo[1,2-a]pyridine-2-carboxylic acid
- CBNumber
- CB42534181
- Molecular Formula
- C8H5BrN2O2
- Formula Weight
- 241
- MOL File
- 1026201-45-5.mol
8-bromoimidazo[1,2-a]pyridine-2-carboxylic acid Property
- storage temp.
- 2-8°C
- Appearance
- White to yellow Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- B702588
- Product name
- 8-Bromoimidazo[1,2-a]pyridine-2-carboxylicAcid
- Packaging
- 100mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- B702588
- Product name
- 8-Bromoimidazo[1,2-a]pyridine-2-carboxylicAcid
- Packaging
- 500mg
- Price
- $220
- Updated
- 2021/12/16
- Product number
- CS-W000732
- Product name
- 8-Bromoimidazo[1,2-a]pyridine-2-carboxylicacid
- Purity
- >97.0%
- Packaging
- 5g
- Price
- $259
- Updated
- 2021/12/16
- Product number
- CS-W000732
- Product name
- 8-Bromoimidazo[1,2-a]pyridine-2-carboxylicacid
- Purity
- >97.0%
- Packaging
- 1g
- Price
- $74
- Updated
- 2021/12/16
- Product number
- 123909
- Product name
- 8-Bromoimidazo[1,2-a]pyridine-2-carboxylicacid
- Purity
- 95+%
- Packaging
- 1g
- Price
- $446
- Updated
- 2021/12/16
8-bromoimidazo[1,2-a]pyridine-2-carboxylic acid Chemical Properties,Usage,Production
Synthesis
1038393-19-9
1026201-45-5
General procedure for the synthesis of 8-bromoimidazo[1,2-a]pyridine-2-carboxylic acid from ethyl 8-bromoimidazo[1,2-a]pyridine-2-carboxylate: Intermediate 37 (2.02 g, 7.4 mmol) was dissolved in a solvent mixture of dioxane and water (16 mL dioxane/4 mL water) and the mixture was cooled in an ice bath. Subsequently, lithium hydroxide (LiOH, 355 mg, 14.8 mmol) was added and the resulting mixture was stirred and reacted at room temperature for 20 hours. After completion of the reaction, the volatile solvent was removed by distillation under reduced pressure. The mixture was cooled again in an ice bath and slowly acidified with aqueous 1 N hydrochloric acid (HCl) to pH 4. The precipitated solid was collected by filtration, washed with cold water (10 mL), and finally dried under vacuum to give Intermediate 39 (1.5 g, 88% yield).
References
[1] Patent: WO2010/70008, 2010, A1. Location in patent: Page/Page column 58
[2] Patent: WO2008/57209, 2008, A1. Location in patent: Page/Page column 51-52
8-bromoimidazo[1,2-a]pyridine-2-carboxylic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 8-bromoimidazo[1,2-a]pyridine-2-carboxylic acid manufacturers
- Product
- 8-bromoimidazo[1,2-a]pyridine-2-carboxylic acid 1026201-45-5
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- JD724
- Release date
- 2019-09-02