2-Chloro-8-nitroquinoline
- Product Name
- 2-Chloro-8-nitroquinoline
- CAS No.
- 4225-86-9
- Chemical Name
- 2-Chloro-8-nitroquinoline
- Synonyms
- NSC 263744;MFCD00160589;2-Chloro-8-nitroquinoline;Quinoline, 2-chloro-8-nitro-
- CBNumber
- CB42549765
- Molecular Formula
- C9H5ClN2O2
- Formula Weight
- 208.6
- MOL File
- 4225-86-9.mol
2-Chloro-8-nitroquinoline Property
- Melting point:
- 149℃ (ethanol )
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- Appearance
- White to light yellow Solid
N-Bromosuccinimide Price
- Product number
- C612265
- Product name
- 2-Chloro-8-nitroquinoline
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- FC135050
- Product name
- 2-Chloro-8-nitroquinoline
- Packaging
- 250mg
- Price
- $85
- Updated
- 2021/12/16
- Product number
- FC135050
- Product name
- 2-Chloro-8-nitroquinoline
- Packaging
- 500mg
- Price
- $150
- Updated
- 2021/12/16
- Product number
- FC135050
- Product name
- 2-Chloro-8-nitroquinoline
- Packaging
- 2g
- Price
- $434
- Updated
- 2021/12/16
- Product number
- FC135050
- Product name
- 2-Chloro-8-nitroquinoline
- Packaging
- 1g
- Price
- $255
- Updated
- 2021/12/16
2-Chloro-8-nitroquinoline Chemical Properties,Usage,Production
Synthesis
612-62-4
4225-86-9
A mixed solution of nitric acid (16 mL) and sulfuric acid (8 mL) was slowly added dropwise to a solution of sulfuric acid (150 mL) containing 2-chloroquinoline (61.1 mmol) at 20 °C, keeping the reaction temperature at 0 °C. Subsequently, the reaction mixture was warmed up to 40 °C and maintained for 30 min. Upon completion of the reaction, the reaction was quenched with ice water (800 mL). The precipitated solid product was collected by filtration and purified by fast chromatography (eluent ratio of 20:1 petroleum ether/ethyl acetate) to finally obtain the target compound 2-chloro-8-nitroquinoline in 64% yield as a yellow solid.
References
[1] Patent: WO2009/23844, 2009, A2. Location in patent: Page/Page column 112
[2] Patent: WO2010/21797, 2010, A1. Location in patent: Page/Page column 75-76
[3] Patent: WO2010/24980, 2010, A1. Location in patent: Page/Page column 93; 94
[4] ChemMedChem, 2018,
[5] Australian Journal of Chemistry, 2003, vol. 56, # 1, p. 39 - 44
2-Chloro-8-nitroquinoline Preparation Products And Raw materials
Raw materials
Preparation Products
2-Chloro-8-nitroquinoline Suppliers
- Tel
- 400-6009262 16621234537
- Fax
- 021-64823266
- chenyj@titansci.com
- Country
- China
- ProdList
- 14101
- Advantage
- 59
- Tel
- 18030648795
- Fax
- 028-61777050
- sales@cdforestchem.com
- Country
- China
- ProdList
- 1997
- Advantage
- 58
- Tel
- 021-58170097
- info@topbiochem.com
- Country
- China
- ProdList
- 9510
- Advantage
- 58
- Tel
- 021-60343070
- Fax
- 021-35122006
- Country
- China
- ProdList
- 12740
- Advantage
- 55
- Tel
- +86-021-50935922
- Fax
- +86-021-33847795
- Country
- China
- ProdList
- 7865
- Advantage
- 55
- Tel
- 400-164-7117 13681763483
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 42446
- Advantage
- 60
- Tel
- 微信 17321281695 18019252918
- Fax
- 17321281695
- sale@amkchem.com
- Country
- China
- ProdList
- 15136
- Advantage
- 55
- Tel
- 021-60455363 18019463053
- Fax
- 50966098
- sales@coolpharm.com
- Country
- China
- ProdList
- 12346
- Advantage
- 58
- Tel
- 023-61183015; 13271886913
- kangheyuecheng@163.com
- Country
- China
- ProdList
- 292
- Advantage
- 55
- Tel
- 025-83453382-8005
- Fax
- 025-83453382
- sale@parabiochem.com
- Country
- China
- ProdList
- 9595
- Advantage
- 55
View Lastest Price from 2-Chloro-8-nitroquinoline manufacturers
- Product
- 2-Chloro-8-nitroquinoline 4225-86-9
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-11
- Product
- 2-Chloro-8-nitroquinoline 4225-86-9
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 200KG
- Release date
- 2018-12-23