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quinuclidin-4-ylMethanaMine

Product Name
quinuclidin-4-ylMethanaMine
CAS No.
67496-78-0
Chemical Name
quinuclidin-4-ylMethanaMine
Synonyms
4-Aminomethylquinuclidine;quinuclidin-4-ylMethanaMine;Quinnclidine-4-ylmethylamine;1-Azabicyclo[2.2.2]octane-4-methanamine;1-AZABICYCLO[2.2.2]OCTAN-4-YLMETHANAMINE;1-(1-Azabicyclo[2.2.2]oct-4-yl)methanamine;(1-Aza-bicyclo[2.2.2]oct-4-yl)-methylamine;C-(1-Aza-bicyclo[2.2.2]oct-4-yl)-MethylaMine;1-Azabicyclo[2.2.2]octane-4-methanamine 4-Aminomethylquinuclidine
CBNumber
CB42561361
Molecular Formula
C8H16N2
Formula Weight
140.23
MOL File
67496-78-0.mol
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quinuclidin-4-ylMethanaMine Property

Boiling point:
186℃
Density 
1.04
Flash point:
63℃
storage temp. 
2-8°C(protect from light)
pka
10.67±0.10(Predicted)
Appearance
Light yellow to yellow Liquid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

TRC
Product number
Q990138
Product name
Quinuclidin-4-ylmethanamine
Packaging
50mg
Price
$200
Updated
2021/12/16
Chemenu
Product number
CM243490
Product name
Quinuclidin-4-ylmethanamine
Purity
95%
Packaging
1g
Price
$388
Updated
2021/12/16
Alichem
Product number
67496780
Product name
Quinuclidin-4-ylmethanamine
Packaging
1g
Price
$406.7
Updated
2021/12/16
Crysdot
Product number
CD11074654
Product name
Quinuclidin-4-ylmethanamine
Purity
98%
Packaging
1g
Price
$411
Updated
2021/12/16
Ambeed
Product number
A244320
Product name
Quinuclidin-4-ylmethanamine
Purity
98%
Packaging
1g
Price
$474
Updated
2021/12/16
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quinuclidin-4-ylMethanaMine Chemical Properties,Usage,Production

Synthesis

26458-78-6

67496-78-0

E) Synthesis of quinuclidinium-4-ylmethylamine 4-Cyanoquinuclidine (0.30 g, 2.2 mmol) was dissolved in ether (5 mL) and slowly added to an ether suspension of lithium aluminum hydride (LAH, 0.167 g, 4.41 mmol). The reaction system was cooled at 0 °C and additional ether (15 mL) was added. Subsequently, the reaction mixture was stirred at 23 °C for 3 hours. Upon completion of the reaction, the reaction was quenched with sodium sulfate decahydrate and stirring was continued for 30 minutes. Next, ethyl acetate was added and after 30 minutes, diatomaceous earth was added and the suspension was filtered through diatomaceous earth. The filtrate was concentrated to dryness to give the oily product quinuclidinium-4-ylmethylamine (0.310 g, quantitative yield). The product was used directly in the subsequent reaction without further purification. 1H NMR (400 MHz, CDCl3) δ ppm: 1.31-1.40 (6H, m), 2.43 (2H, s), 2.86-2.94 (6H, m).

References

[1] Patent: WO2008/124757, 2008, A1. Location in patent: Page/Page column 55
[2] Patent: US2013/79319, 2013, A1. Location in patent: Paragraph 0199; 0200
[3] Patent: US5399562, 1995, A
[4] Patent: US6281226, 2001, B1
[5] Patent: US2009/88418, 2009, A1. Location in patent: Page/Page column 20

quinuclidin-4-ylMethanaMine Preparation Products And Raw materials

Raw materials

Preparation Products

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quinuclidin-4-ylMethanaMine Suppliers

skychemical Co.Ltd
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021-20958197 20965099
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China
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Bide Pharmatech Ltd.
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ShangHai Wisacheam Pharmaceutical Co., Ltd.
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Shanghai Send Pharmaceutical Technology Co., Ltd.
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View Lastest Price from quinuclidin-4-ylMethanaMine manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
1-(1-Azabicyclo[2.2.2]oct-4-yl)methanamine 67496-78-0
Price
US $2.20-8.80/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2025-06-17
Career Henan Chemical Co
Product
quinuclidin-4-ylMethanaMine 67496-78-0
Price
US $1.00/KG
Min. Order
1KG
Purity
95-99%
Supply Ability
1ton
Release date
2019-12-31

67496-78-0, quinuclidin-4-ylMethanaMineRelated Search:


  • quinuclidin-4-ylMethanaMine
  • 1-Azabicyclo[2.2.2]octane-4-methanamine
  • 4-Aminomethylquinuclidine
  • 1-AZABICYCLO[2.2.2]OCTAN-4-YLMETHANAMINE
  • C-(1-Aza-bicyclo[2.2.2]oct-4-yl)-MethylaMine
  • 1-Azabicyclo[2.2.2]octane-4-methanamine 4-Aminomethylquinuclidine
  • Quinnclidine-4-ylmethylamine
  • (1-Aza-bicyclo[2.2.2]oct-4-yl)-methylamine
  • 1-(1-Azabicyclo[2.2.2]oct-4-yl)methanamine
  • 67496-78-0