5-CHLORO-1H-PYRAZOLO[3,4-C]PYRIDINE

Product Name: 5-CHLORO-1H-PYRAZOLO[3,4-C]PYRIDINE
CAS No.: 76006-08-1
Chemical Name: 5-CHLORO-1H-PYRAZOLO[3,4-C]PYRIDINE
Synonyms: 5-chloro-1H-pyrazolo[3;5-Chloro-1H-pyrazolo[3,4-...;5-CHLORO-1H-PYRAZOLO[3,4-C]PYRIDINE;1H-Pyrazolo[3,4-c]pyridine,5-chloro-;3-Bromo-1H-pyrrolo [2,3-c] pyridine-7-ol;5-chloro-1h-pyrazole and [3, 4-c] pyridine
CBNumber: CB4256573
Molecular Formula: C6H4ClN3
Formula Weight: 153.57
MOL File: 76006-08-1.mol

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5-CHLORO-1H-PYRAZOLO[3,4-C]PYRIDINE Property

Melting point:: 184-185 °C
Boiling point:: 357.5±22.0 °C(Predicted)
Density: 1.531±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
pka: 9.74±0.40(Predicted)

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Safety

HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: B418670
Product name: 5-Chloro-1H-pyrazolo[3,4-c]pyridine
Packaging: 50mg
Price: $45
Updated: 2021/12/16

Matrix Scientific

Product number: 073017
Product name: 5-Chloro-1H-pyrazolo[3,4-c]pyridine
Purity: 95+%
Packaging: 1g
Price: $145
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H32-5-1D
Product name: 5-Chloro-1H-pyrazolo[3,4-c]pyridine
Packaging: 1g
Price: $225
Updated: 2021/12/16

Matrix Scientific

Product number: 073017
Product name: 5-Chloro-1H-pyrazolo[3,4-c]pyridine
Purity: 95+%
Packaging: 5g
Price: $438
Updated: 2021/12/16

AK Scientific

Product number: W8308
Product name: 5-Chloro-1H-pyrazolo[3,4-c]pyridine
Packaging: 1g
Price: $489
Updated: 2021/12/16

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5-CHLORO-1H-PYRAZOLO[3,4-C]PYRIDINE Chemical Properties,Usage,Production

Uses

5-Chloro-1H-pyrazolo[3,4-C]pyridine is a pyrazolo aromatic heterocyclic compound and an important organic synthesis intermediate. And it is widely used in the preparation of medicines, pesticides and other compounds.

Synthesis

2-Chloro-5-fluoro-4-aldolpyridine (0.49 mol, 75.0 g), methoxyamine hydrochloride (0.51 mol, 42.6 g) and potassium carbonate (0.59 mol, 81.5 g) were combined at room temperature were respectively added to the reactor containing 1L of tetrahydrofuran solution. After stirring overnight at room temperature, it was filtered and the filtrate was concentrated to give a residue. 85 wt% aqueous hydrazine hydrate solution (1.47 mol) was added dropwise to the residue, and the residue was refluxed overnight, and the progress of the reaction was monitored by LC-MS until the reaction was completed. After evaporating off excess hydrazine, 1 L of water was added to the mixture, and after a precipitate was deposited, it was filtered, washed with water and dried to obtain a gray powder. The gray powder was dissolved in tetrahydrofuran, 10 mL of trifluoroacetic acid was added to reflux for 1 hour, the reaction mixture was concentrated, washed three times with water and tert-butyl methyl ether to obtain a light gray powder of pyrazoloheterocyclic compound (5-Chloro-1H-pyrazolo[3,4-c]pyridine) powder, yield 86%, and purity ≥95%. 1H-NMR (CD3OD-d4, 400MHz) δ: 7.82 (s, 1H), 8.15 (s, 1H), 8.80 (s, 1H).

5-CHLORO-1H-PYRAZOLO[3,4-C]PYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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5-CHLORO-1H-PYRAZOLO[3,4-C]PYRIDINE Suppliers

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View Lastest Price from 5-CHLORO-1H-PYRAZOLO[3,4-C]PYRIDINE manufacturers

Career Henan Chemical Co

Product: 5-CHLORO-1H-PYRAZOLO[3,4-C]PYRIDINE 76006-08-1
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200kg
Release date: 2019-12-25

76006-08-1, 5-CHLORO-1H-PYRAZOLO[3,4-C]PYRIDINERelated Search:

6-Chloro-1,3-dihydro-2H-pyrrolo[3,2-c]pyridin-2-one 5-CHLORO-1H-PYRROLO[3,2-B] PYRIDINE 5-CHLORO-1,3-DIHYDRO-2H-PYRROLO[3,2-B] PYRIDIN-2-ONE 1H-Pyrrolo[2,3-b]pyridine-3-carbonitrile, 5-chloro- 5-CHLORO (1H)INDAZOLE 5-chloro-1,2,3,4-tetrahydro-1,6-naphthyridine 5-Chloro-6-azaindole-3-carboxaldehyde 5-Chloro-1H-pyrazolo[4,3-b]pyridine 5-Chloro-1,2,3,4-tetrahydroisoquinoline 5-Chloro-[1,2,4]triazolo[1,5-a]pyridine 5-CHLORO-3-HYDROXY (1H)INDAZOLE 5-CHLORO-1H-INDOL-3-METHYLAMINE 5-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid 5-Chloro-1,3,4-thiadiazol-2-ylamine 6-Chloro-3H-1,2,3-triazolo[4,5-c]pyridine 5-CHLORO-1H-PYRROLO[2,3-C]PYRIDINE 5-Chloro-7-azaindole-3-carboxaldehyde 5-Chloro-7-azaindole-3-carboxylic acid Methyl ester

5-CHLORO-1H-PYRAZOLO[3,4-C]PYRIDINE

1H-Pyrazolo[3,4-c]pyridine,5-chloro-

5-chloro-1H-pyrazolo[3

5-Chloro-1H-pyrazolo[3,4-...

3-Bromo-1H-pyrrolo [2,3-c] pyridine-7-ol

5-chloro-1h-pyrazole and [3, 4-c] pyridine

76006-08-1

Heterocycle-Pyridine series