HTS 01037
- Product Name
- HTS 01037
- CAS No.
- 682741-29-3
- Chemical Name
- HTS 01037
- Synonyms
- HTS 01037;HTS 01037 (HTS01037;4-{[2-(methoxycarbonyl)-5-(2-thinyl)-3-thienyl]amino}-4-oxo-2-butenoic acid;[2,2'-Bithiophene]-5-carboxylic acid, 4-[(3-carboxy-1-oxo-2-propen-1-yl)amino]-, 5-methyl ester
- CBNumber
- CB42591315
- Molecular Formula
- C14H11NO5S2
- Formula Weight
- 337.37
- MOL File
- 682741-29-3.mol
HTS 01037 Property
- Boiling point:
- 621.2±55.0 °C(Predicted)
- Density
- 1.493±0.06 g/cm3(Predicted)
- storage temp.
- RT
- solubility
- Soluble in DMSO (up to 50 mg/ml)
- pka
- 3.39±0.10(Predicted)
- form
- solid
- color
- Yellow
- Stability:
- Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
N-Bromosuccinimide Price
- Product number
- 10699
- Product name
- HTS 01037
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $32
- Updated
- 2024/03/01
- Product number
- 10699
- Product name
- HTS 01037
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $70
- Updated
- 2024/03/01
- Product number
- 10699
- Product name
- HTS 01037
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $153
- Updated
- 2024/03/01
- Product number
- 10699
- Product name
- HTS 01037
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $305
- Updated
- 2024/03/01
- Product number
- CS-6858
- Product name
- HTS01037
- Purity
- 99.76%
- Packaging
- 25mg
- Price
- $312
- Updated
- 2021/12/16
HTS 01037 Chemical Properties,Usage,Production
Description
Adipocyte fatty acid binding protein (A-
Uses
HTS 01037 is an inhibitor of fatty acid binding protein and a competitive antagonist of protein-protein interactions mediated by AFABP/aP2.
Definition
ChEBI: HTS 01037 is a ring assembly and a member of thiophenes.
References
1) Hertzel?et al. (2009),?Identification and characterization of a small molecule inhibitor of Fatty Acid binding proteins; J. Med. Chem,?52?6024 2) Long?et al. (2012),?Fatty acids induce leukotriene C4 synthesis in macrophages in a fatty acid binding protein-dependent manner;?Biochim. Biophys. Acta,?1831?1199 3) Xu?et al.?(2015),?Uncoupling lipid metabolism from inflammation through fatty acid binding protein-dependent expression of USP2; Mol. Cell. Biol.,?35?1055 4) Steen?et al. (2016),?FABP4/aP2 regulates macrophage redox signaling and inflammasome activation via control of UCP2; Mol. Cell. Biol.,?37 e00282 5) Boss?et al.?(2015),?FABP4 inhibition suppresses PPARgamma activity and VLDL-induced foam cell formation in IL-4-polarized human macrophages; Atherosclerosis,?240?424
HTS 01037 Preparation Products And Raw materials
Raw materials
Preparation Products
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