4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-(1,1'-biphenyl)-2-carbonitrile

Product Name: 4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-(1,1'-biphenyl)-2-carbonitrile
CAS No.: 138401-24-8
Chemical Name: 4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-(1,1'-biphenyl)-2-carbonitrile
Synonyms: Irbint-A04;CyanoIrbesartan;4'-[(2-Butyl-4-oxo-1;Irbesartan Alkylation;Irbesartan IMpurity B;Irbesartan Impurity 12;Irbesartan Cyano IMpurity;He sand hydrocarbon compound;4'-[(2-Butyl-4-oxo-1,3-diazasp;diazaspiro[4.4]non-1-en-3-yl)methyl]-
CBNumber: CB4259312
Molecular Formula: C25H27N3O
Formula Weight: 385.5
MOL File: 138401-24-8.mol

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4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-(1,1'-biphenyl)-2-carbonitrile Property

Melting point:: 95-97°C
Boiling point:: 576.5±60.0 °C(Predicted)
Density: 1.15
vapor pressure: 0Pa at 20℃
storage temp.: Sealed in dry,Room Temperature
solubility: soluble in Methanol
form: Crystalline
pka: 2.45±0.20(Predicted)
color: White to Almost white
LogP: 3.7 at 20℃ and pH7
Surface tension: 72.5mN/m at 1.025mg/L and 20℃
CAS DataBase Reference: 138401-24-8(CAS DataBase Reference)

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Safety

Hazard Codes: N
Risk Statements: 50/53
Safety Statements: 60-61
RIDADR: 3077
HS Code: 2933.29.4300

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical

Product number: B4143
Product name: 2-Butyl-3-[[2'-cyano-[1,1'-biphenyl]-4-yl]methyl]-1,3-diazaspiro[4,4]non-1-en-4-one
Purity: >97.0%(N)
Packaging: 1g
Price: $78
Updated: 2024/03/01

TCI Chemical

Product number: B4143
Product name: 2-Butyl-3-[[2'-cyano-[1,1'-biphenyl]-4-yl]methyl]-1,3-diazaspiro[4,4]non-1-en-4-one
Purity: >97.0%(N)
Packaging: 5g
Price: $270
Updated: 2024/03/01

TRC

Product number: B693590
Product name: 4''-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-[1,1''-Biphenyl]-2-carbonitrile
Packaging: 1g
Price: $85
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB19496
Product name: 4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-[1,1'-biphenyl]-2-carbonitrile
Packaging: 1g
Price: $149.9
Updated: 2021/12/16

AK Scientific

Product number: I709
Product name: 4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]biphenyl-2-carbonitrile
Packaging: 5g
Price: $227
Updated: 2021/12/16

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4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-(1,1'-biphenyl)-2-carbonitrile Chemical Properties,Usage,Production

Chemical Properties

4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-(1,1'-biphenyl)-2-carbonitrile is WHite Solid

Uses

4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-(1,1'-biphenyl)-2-carbonitrile is a butyldiazaspirononenone derivative used in the preparation of acetylcholinesterase inhibitors. An impurity found in Irbesartan (I751000).

4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-(1,1'-biphenyl)-2-carbonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

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4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-(1,1'-biphenyl)-2-carbonitrile Suppliers

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View Lastest Price from 4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-(1,1'-biphenyl)-2-carbonitrile manufacturers

Hong Kong Tiansheng New Material Trading Co., Ltd

Product: 4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-[1,1'-Biphenyl]-2-carbonitrile 138401-24-8
Price: US $57.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100ton
Release date: 2021-12-02

Hong Kong Tiansheng New Material Trading Co., Ltd

Product: 4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-[1,1'-Biphenyl]-2-carbonitrile 138401-24-8
Price: US $16.00/Kg/Bag
Min. Order: 1Kg/Bag
Purity: 99%
Supply Ability: 23kg
Release date: 2022-01-11

Career Henan Chemical Co

Product: 4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-(1,1'-biphenyl)-2-carbonitrile 138401-24-8
Price: US $1.00/KG
Min. Order: 1KG
Purity: 40%-99%
Supply Ability: 1000kg
Release date: 2018-08-20

138401-24-8, 4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-(1,1'-biphenyl)-2-carbonitrileRelated Search:

1-AMINO-1-CYCLOPENTANECARBOXAMIDE 3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-2-[1-[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]pentan-2-yl]-1,3-diazaspiro[4.4]non-1-en-4-one Irbesartan IMpurity Irbesartan Impurity 15 Sodium Salt Irbesartan Impurity 4 1-[(2'-Cyano[1,1'-biphenyl]-4-yl)MethylaMino]-N-pentanoylcyclopentanecarboxaMide Irbesartan N--D-Glucuronide Irbesartan Irbesartan Impurity DeMethyl Irbesartan Irbesartan Impurity 14 IRBESARTAN RELATED COMPOUND A (25 MG) (1-PENTANOYLAMINO-CYCLOPENTANECARBOXYLIC ACID [2'-(1H-TETRAZOL-5-YL)-BIPHENYL-4-YLMETHYL]-AMIDE) L-Serine methyl ester hydrochloride 2-Butyl-4-spirocyclopentane-2-imidazolin-5-one hydrochloride [1,1'-Biphenyl]-2-carboxamide, 4'-[(2-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]- THIOGLYCOLIC ACID N-BUTYL ESTER Irbesartan 4'-Methyl-2-cyanobiphenyl

[1,1'-BIPHENYL]-2-CARBONITRILE, 4'-[(2-BUTYL-4-OXO-1,3-DIAZASPIRO[4.4]NON-1-EN-3-YL)METHYL]-

[1,1'-BIPHENYL]-2-CARBONITRILE-4-[(2-BUTYL-4-OXO-1,3-DIAZASPIRO[4.4]NON-1-EN-3-YL)METHYL]

Irbesartan Alkylation

He sand hydrocarbon compound

3-diazaspiro[4.4]non-1-en-3-yl)methyl]-(1

4'-[(2-Butyl-4-oxo-1

Irbint-A04

Irbesartan Impurity 12

[1.1’-Biphenyl]-2-Carbonitrile-4-[(2-Butyl-4-Oxo-1.3- Diazaspiro[4.4]

4'-[(2-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-(1,1'-biphenyl)-2-carbonitrile

4'-[(2-N-BUTYL-4-OXO-1,3-DIAZASPIRO[4.4]NON-1-EN-3-YL)METHYL]-[1,1'-BIPHENYL]-2-CARBONITRILE

[1.1'-Biphenyl]-2-carbonitrile-4-[(2-butyl-4-oxo-1.3-diazaspiro[4.4]non-1-en-3-y

4'-[(2-Butyl-4-oxo-1,3-diazasp

4-(2-butyl-1,3-diazaspiro-[4-4] no-1-en-3-yl-methyl)biphenyl-2-carbonitrile

4'-((2-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-ene-3-yl)methyl)(1,1'-biphenyl)-2-carbonitrile

[1,1'-Biphenyl]-2-carbonitrile,4'-[(2-butyl-4-oxo-1,3-

diazaspiro[4.4]non-1-en-3-yl)methyl]-

4-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl

Irbesartan IMpurity B

Irbesartan Cyano IMpurity

5-({2-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl}Methyl)-2-phenylbenzonitrile

CyanoIrbesartan

2-[4-[(8-butyl-6-oxo-7,9-diazaspiro[4.4]non-8-en-7-yl)methyl]phenyl]benzonitrile

Irbesartan impurity 1/Irbesartan Cyano Impurity/4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]biphenyl-2-carbonitrile

2-Butyl-3-[[2'-cyano-[1,1'-biphenyl]-4-yl]methyl]-1,3-diazaspiro[4,4]non-1-en-4-one &gt

4'-[(2-BUTYL-4-OXO-1,3-DIAZASPIRO[4.4]NON-1-EN-3-YL)METHYL]-(1,1'-BIPHENYL)-2-CARBONITRILE/138401-24-8

1-[2'-cyanobipheynl-4-yl)methyl]-2n-butyl-4--spirocyclopentane-2-imidazolin-5-one

2-n-Butyl-3-(2-cyanobiphenyl-4yl)methyl-1,3-diaza-spiro[4,4]non-1-en-4-one

4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]b...

C25H27N3O 4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-(1,1'-biphenyl)-2-carbonitrile 138401-24-8

4' -[(2-Buty1-4- oxo-1,3-diazaspiro[4.4]non-1-en-3yl) methylbiphenyl-2- carbonitrile

4'-[(2-butyl-4-oxo-1,3-diazaspiro [4,4] non-1-en-3-yl) methyl [1,1' - bis phenyl]-2-carbonitrile

2-Butyl-3-[[2'-cyano-[1,1'-biphenyl]-4-yl]methyl]-1,3-diazaspiro[4,4]non-1-en-4-one, ≥ 97.0%

2-Butyl-3-[[2'-cyano-[1,1'-biphenyl]-4-yl]methyl]-1,3-diazaspiro[4,4]non-1-en-4-one

4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-[1,1'-Biphenyl]-2-carbonitrile

[1,1'-Biphenyl]-2-carbonitrile,4'-[(2-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]

2-Butyl-3-[[2'-(cyano)biphenyl-4-yl]methyl]-1,3-diazaspiro[4.4]non-1-en-4-one

Irbesartan Cyano Impurity 4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3- yl)methyl]biphenyl-2-carbonitrile

4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]biphenyl-2-carbonitrile

138401-24-8

138401-24-6

C25H27N3O

Aromatics

Heterocycles

Intermediates & Fine Chemicals

Pharmaceuticals

Chemical intermediate for Sartan

INTERMEDIATESOF

Irbesartan

(intermediate of irbesartan)