4-(N-Boc-N-MethylaMino)cyclohexanol
Uses Application- Product Name
- 4-(N-Boc-N-MethylaMino)cyclohexanol
- CAS No.
- 1256633-24-5
- Chemical Name
- 4-(N-Boc-N-MethylaMino)cyclohexanol
- Synonyms
- 4-(N-Boc-N-MethylaMino)cyclohexanol;Carbamic acid,N-(4-hydroxycyclohexyl)-N-methyl-, 1,1-dimethylethyl ester
- CBNumber
- CB42597140
- Molecular Formula
- C12H23NO3
- Formula Weight
- 229.32
- MOL File
- 1256633-24-5.mol
4-(N-Boc-N-MethylaMino)cyclohexanol Property
- Boiling point:
- 319.2±31.0 °C(Predicted)
- Density
- 1.05±0.1 g/cm3(Predicted)
- pka
- 15.09±0.40(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330Rinse mouth.
N-Bromosuccinimide Price
- Product number
- Y5983
- Product name
- tert-Butyl4-hydroxycyclohexyl(methyl)carbamate
- Packaging
- 5g
- Price
- $458
- Updated
- 2021/12/16
- Product number
- CHM0096859
- Product name
- TERT-BUTYL-(4-HYDROXYCYCLOHEXYL)METHYLCARBAMATE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $497.83
- Updated
- 2021/12/16
- Product number
- CD13025151
- Product name
- 4-(N-Boc-N-methylamino)cyclohexanol
- Purity
- 95+%
- Packaging
- 5g
- Price
- $327
- Updated
- 2021/12/16
- Product number
- CM324211
- Product name
- 4-(N-Boc-N-methylamino)cyclohexanol
- Purity
- 95%
- Packaging
- 10g
- Price
- $438
- Updated
- 2021/12/16
4-(N-Boc-N-MethylaMino)cyclohexanol Chemical Properties,Usage,Production
Uses
4-(N-BOC-N-methylamino)cyclohexanol can be used as a pharmaceutical synthesis intermediate.
Application
4-(N-BOC-N-methylamino)cyclohexanol (30 g, 149.1 mmol, 1 eq.), triethylamine (22.87 mL, 164 mmol, 1.1 eq.), and N,N-dimethylpyridine-4-amine (DMAP) (1.83 g, 14.98 mmol, 0.1 eq.) were dissolved in anhydrous dichloromethane (500 mL) and cooled to 0 °C in an ice bath. Methanesulfonyl chloride (12.12 mL, 156.6 mmol, 1.05 equivalents) was added dropwise. After the addition was complete, the reaction mixture was warmed to room temperature and stirred for 16 hours. The reaction mixture was washed with water (3 × 100 mL) and saturated sodium bicarbonate (3 × 100 mL). The combined washings were back-extracted with dichloromethane. The combined organic compounds were dried over Na2SO4 and concentrated to give 40.83 g (146.2 mmol) of 1-(tert-butyloxycarbonyl)piperidine-4-ylmethanesulfonate (compound 1013, 98% yield), which was a grayish-white solid and could be used without further processing.
4-(N-Boc-N-MethylaMino)cyclohexanol Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-(N-Boc-N-MethylaMino)cyclohexanol manufacturers
- Product
- 4-(N-Boc-N-MethylaMino)cyclohexanol 1256633-24-5
- Price
- US $1.30/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 1kg,10kg,100kg
- Release date
- 2020-10-27