ChemicalBook > CAS DataBase List > (2E)-3-(4'-Hydroxy-3'-tricyclo[3.3.1.13,7]dec-1-yl[1,1'-biphenyl]-4-yl)-2-propenoic acid

(2E)-3-(4'-Hydroxy-3'-tricyclo[3.3.1.13,7]dec-1-yl[1,1'-biphenyl]-4-yl)-2-propenoic acid

Product Name
(2E)-3-(4'-Hydroxy-3'-tricyclo[3.3.1.13,7]dec-1-yl[1,1'-biphenyl]-4-yl)-2-propenoic acid
CAS No.
496868-77-0
Chemical Name
(2E)-3-(4'-Hydroxy-3'-tricyclo[3.3.1.13,7]dec-1-yl[1,1'-biphenyl]-4-yl)-2-propenoic acid
Synonyms
ST 1926;Adarotene;Adarotene (ST1926);ST 1926;ST-1926;ST1926;ADAROTENE;ST 1926;ST-1926;ST1926;Inhibitor,inhibit,Apoptosis,ST-1926,ST 1926,Adarotene;(E)-3-[4-[3-(1-adamantyl)-4-hydroxyphenyl]phenyl]prop-2-enoic acid;(2E)-3-(4'-Hydroxy-3'-tricyclo[3.3.1.13,7]dec-1-yl[1,1'-biphenyl]-4-yl)-2-propenoic acid;2-Propenoic acid, 3-(4'-hydroxy-3'-tricyclo[3.3.1.13,7]dec-1-yl[1,1'-biphenyl]-4-yl)-, (2E)-
CBNumber
CB42614326
Molecular Formula
C25H26O3
Formula Weight
374.47
MOL File
496868-77-0.mol
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(2E)-3-(4'-Hydroxy-3'-tricyclo[3.3.1.13,7]dec-1-yl[1,1'-biphenyl]-4-yl)-2-propenoic acid Property

Melting point:
>240 °C
Boiling point:
574.1±50.0 °C(Predicted)
Density 
1.257
storage temp. 
Store at -20°C
solubility 
≥37.4 mg/mL in DMSO; insoluble in H2O; ≥10.97 mg/mL in EtOH with gentle warming and ultrasonic
form 
solid
pka
-95.54±0.10(Predicted)
color 
White to green
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
29807
Product name
Adarotene
Packaging
5mg
Price
$68
Updated
2024/03/01
Cayman Chemical
Product number
29807
Product name
Adarotene
Packaging
10mg
Price
$121
Updated
2024/03/01
Cayman Chemical
Product number
29807
Product name
Adarotene
Packaging
25mg
Price
$286
Updated
2024/03/01
Cayman Chemical
Product number
29807
Product name
Adarotene
Packaging
50mg
Price
$535
Updated
2024/03/01
ApexBio Technology
Product number
A3143
Product name
Adarotene
Packaging
5mg
Price
$68
Updated
2021/12/16
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(2E)-3-(4'-Hydroxy-3'-tricyclo[3.3.1.13,7]dec-1-yl[1,1'-biphenyl]-4-yl)-2-propenoic acid Chemical Properties,Usage,Production

Uses

Adarotene has been found to have antitumor activity against different types of cancer, including acute myeloid leukemia, primary effusion lymphoma, prostate cancer and glioma. It may also be useful in treating acute lung injury through inflammation and ROS suppression via inactivating TLR4?/NF-?κB and p38?/ERK1?/2 signaling pathways.

target

RAR β

(2E)-3-(4'-Hydroxy-3'-tricyclo[3.3.1.13,7]dec-1-yl[1,1'-biphenyl]-4-yl)-2-propenoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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(2E)-3-(4'-Hydroxy-3'-tricyclo[3.3.1.13,7]dec-1-yl[1,1'-biphenyl]-4-yl)-2-propenoic acid Suppliers

China 54 India 1 United States 9 Global 64
Chembest Research Laboratories Limited
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+86-21-20908456
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021-50315529
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Codow Chemical Co.,Ltd.
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18620099427
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+86-20-62619665
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Shanghai EFE Biological Technology Co., Ltd.
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View Lastest Price from (2E)-3-(4'-Hydroxy-3'-tricyclo[3.3.1.13,7]dec-1-yl[1,1'-biphenyl]-4-yl)-2-propenoic acid manufacturers

Career Henan Chemical Co
Product
(2E)-3-(4'-Hydroxy-3'-tricyclo[3.3.1.13,7]dec-1-yl[1,1'-biphenyl]-4-yl)-2-propenoic acid 496868-77-0
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1lg; 2kg; 5kg; 10kg; 100kg
Release date
2019-08-31

496868-77-0, (2E)-3-(4'-Hydroxy-3'-tricyclo[3.3.1.13,7]dec-1-yl[1,1'-biphenyl]-4-yl)-2-propenoic acidRelated Search:

3--Phenyl-N-(2,2,2-trichloro-1-((((4-chlorophenyl)amino)carbonothioyl)amino)ethyl)acrylamide WP1066 WP1130 Pracinostat BAY 11-7085 ML264

  • ST 1926;ST-1926;ST1926
  • Adarotene (ST1926)
  • (E)-3-[4-[3-(1-adamantyl)-4-hydroxyphenyl]phenyl]prop-2-enoic acid
  • ADAROTENE;ST 1926;ST-1926;ST1926
  • (2E)-3-(4'-Hydroxy-3'-tricyclo[3.3.1.13,7]dec-1-yl[1,1'-biphenyl]-4-yl)-2-propenoic acid
  • Adarotene
  • ST 1926
  • 2-Propenoic acid, 3-(4'-hydroxy-3'-tricyclo[3.3.1.13,7]dec-1-yl[1,1'-biphenyl]-4-yl)-, (2E)-
  • Inhibitor,inhibit,Apoptosis,ST-1926,ST 1926,Adarotene
  • 496868-77-0