MK-2048

ChemicalBook > CAS DataBase List > MK-2048

Product Name: MK-2048
CAS No.: 869901-69-9
Chemical Name: MK-2048
Synonyms: CS-1529;MK-2048 MK2048;MK-2048 USP/EP/BP;(S)-2-(3-chloro-4-fluorobenzyl)-8-ethyl-10-hydroxy-N,6-diMethyl-1,9-dioxo-1,2,6,7,8,9-hexahydropyrazino[1',2':1,5]pyrrolo[2,3-d]pyridazine-4-carboxaMide;(6S)-2-[(3-Chloro-4-fluorophenyl)methyl]-8-ethyl-1,2,6,7,8,9-hexahydro-10-hydroxy-N,6-dimethyl-1,9-dioxopyrazino[1',2':1,5]pyrrolo[2,3-d]pyridazine-4-carboxamide;Pyrazino[1',2':1,5]pyrrolo[2,3-d]pyridazine-4-carboxamide, 2-[(3-chloro-4-fluorophenyl)methyl]-8-ethyl-1,2,6,7,8,9-hexahydro-10-hydroxy-N,6-dimethyl-1,9-dioxo-, (6S)-
CBNumber: CB42616027
Molecular Formula: C21H21ClFN5O4
Formula Weight: 461.87
MOL File: 869901-69-9.mol

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MK-2048 Property

Density: 1.55
storage temp.: Store at -20°C
solubility: Soluble in DMSO > 10 mM
form: Powder
pka: 6.30±0.40(Predicted)
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: M425030
Product name: MK-2048
Packaging: 10mg
Price: $350
Updated: 2021/12/16

TRC

Product number: M425030
Product name: MK-2048
Packaging: 5mg
Price: $225
Updated: 2021/12/16

ApexBio Technology

Product number: A4072
Product name: (6S)-2-[(3-chloro-4-fluorophenyl)methyl]-8-ethyl-10-hydroxy-N,6-dimethyl-1,9-dioxo-6,7-dihydropyrazino[5,6]pyrrolo[1,3-b]pyridazine-4-carboxamide
Packaging: 10mg
Price: $260
Updated: 2021/12/16

ApexBio Technology

Product number: A4072
Product name: (6S)-2-[(3-chloro-4-fluorophenyl)methyl]-8-ethyl-10-hydroxy-N,6-dimethyl-1,9-dioxo-6,7-dihydropyrazino[5,6]pyrrolo[1,3-b]pyridazine-4-carboxamide
Packaging: 10mM(in 1mL DMSO)
Price: $350
Updated: 2021/12/16

ApexBio Technology

Product number: A4072
Product name: (6S)-2-[(3-chloro-4-fluorophenyl)methyl]-8-ethyl-10-hydroxy-N,6-dimethyl-1,9-dioxo-6,7-dihydropyrazino[5,6]pyrrolo[1,3-b]pyridazine-4-carboxamide
Packaging: 5mg
Price: $190
Updated: 2021/12/16

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MK-2048 Chemical Properties,Usage,Production

Uses

MK-2048 represents a prototype second generation integrase strand transfer inhibitor (INSTI), it was developed with the goal of retaining activity against viruses containing mutations assiciated with resistance of first-generation INSTIs, raltegravir (R100312). MK-2048 exhibits inhibitory activity towards HIV integrase and towards HIV replication. It is four times more effective in inhibiting HIV enzyme integrase than the first generation inhibitor, raltegravir.

target

subtype B integrase

MK-2048 Preparation Products And Raw materials

Raw materials

Preparation Products

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869901-69-9, MK-2048Related Search:

BMS707035 GSK1349572 Raltegravir Entinostat PLX4032 Elvitegravir

Pyrazino[1',2':1,5]pyrrolo[2,3-d]pyridazine-4-carboxamide, 2-[(3-chloro-4-fluorophenyl)methyl]-8-ethyl-1,2,6,7,8,9-hexahydro-10-hydroxy-N,6-dimethyl-1,9-dioxo-, (6S)-

CS-1529

(S)-2-(3-chloro-4-fluorobenzyl)-8-ethyl-10-hydroxy-N,6-diMethyl-1,9-dioxo-1,2,6,7,8,9-hexahydropyrazino[1',2':1,5]pyrrolo[2,3-d]pyridazine-4-carboxaMide

(6S)-2-[(3-Chloro-4-fluorophenyl)methyl]-8-ethyl-1,2,6,7,8,9-hexahydro-10-hydroxy-N,6-dimethyl-1,9-dioxopyrazino[1',2':1,5]pyrrolo[2,3-d]pyridazine-4-carboxamide

MK-2048 USP/EP/BP

MK-2048 MK2048

869901-69-9

C21H21ClFN5O4

Inhibitors