ChemicalBook > CAS DataBase List > BMS707035

BMS707035

Product Name
BMS707035
CAS No.
729607-74-3
Chemical Name
BMS707035
Synonyms
CS-455;BMS707035;BMS707035 USP/EP/BP;BMS 707035;BMS707035;BMS-707035, 10 mM in DMSO;2-(1,1-DIOXOTHIAZINAN-2-YL)-N-[(4-FLUOROPHENYL)METHYL]-5-HYDROXY-1-METHYL-6-OXOPYRIMIDINE-4-CARBOXAMIDE;2-(1,1-Dioxido-1,2-thiazinan-2-yl)-N-(4-fluorobenzyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidine-4-carboxamide;2-(4-((4-fluorobenzyl)carbamoyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)-1l4,2-thiazinane-1,1-bis(olate);4-Pyrimidinecarboxamide, N-[(4-fluorophenyl)methyl]-1,6-dihydro-5-hydroxy-1-methyl-6-oxo-2-(tetrahydro-1,1-dioxido-2H-1,2-thiazin;N-[(4-Fluorophenyl)methyl]-1,6-dihydro-5-hydroxy-1-methyl-6-oxo-2-(tetrahydro-1,1-dioxido-2H-1,2-thiazin-2-yl)-4-pyrimidinecarboxamide
CBNumber
CB72526158
Molecular Formula
C17H19FN4O5S
Formula Weight
410.42
MOL File
729607-74-3.mol
More
Less

BMS707035 Property

Density 
1.54
storage temp. 
Store at -20°C
solubility 
insoluble in EtOH; insoluble in H2O; ≥41 mg/mL in DMSO
form 
Powder
pka
4.50±1.00(Predicted)
color 
Off-white to pink
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

TRC
Product number
B596310
Product name
BMS-707035
Packaging
50mg
Price
$1020
Updated
2021/12/16
ApexBio Technology
Product number
A4069
Product name
BMS-707035
Packaging
5mg
Price
$70
Updated
2021/12/16
ChemScene
Product number
CS-0493
Product name
BMS-707035
Purity
99.95%
Packaging
5mg
Price
$70
Updated
2021/12/16
ApexBio Technology
Product number
A4069
Product name
BMS-707035
Packaging
10mg
Price
$125
Updated
2021/12/16
ChemScene
Product number
CS-0493
Product name
BMS-707035
Purity
99.95%
Packaging
10mg
Price
$125
Updated
2021/12/16
More
Less

BMS707035 Chemical Properties,Usage,Production

Uses

BMS-707035 is a specific HIV-I integrase (IN) inhibitor.

in vivo

BMS-707035 has a low clearance effect in the rat, dog and monkey with moderate to long elimination half-lives in all species[1].
Pharmacokinetic Parameters of BMS-707035 in rat, dog and monkey (IV)[1].

RatMonkeyDog
IV dose (mg/kg)0.8711
CL (ml/min/kg) 9.76.82.0
T1/2(h)4.06.56.0
Vss(L/kg)0.860.870.45
PO dose (mg/kg)4.455.2
Cmax(μM)4.51 6.12 72.8
tmax(h)0.250.250.25
AUC (μM*h) 19.1 19.2162
F (%)8656129

target

HIV-I integrase

BMS707035 Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

BMS707035 Suppliers

China 86 India 2 United States 16 Global 104
Shanghai Boyle Chemical Co., Ltd.
Tel
Fax
86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2922
Advantage
55
Shanghai Paulshine Chemical Co., Ltd.
Tel
+86-021-37788663
Fax
+86-021-37788663
Country
China
ProdList
186
Advantage
64
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
12952
Advantage
65
Dalian Meilun Biotech Co., Ltd.
Tel
0411-62910999 13889544652
Email
sales@meilune.com
Country
China
ProdList
4747
Advantage
58
Shanghai civi chemical technology co.,Ltd
Tel
86-21-34053660
Fax
86-21-34053661
Email
sale@labgogo.com
Country
China
ProdList
9865
Advantage
52
NCE Biomedical Co.,Ltd.
Tel
4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988
Fax
+86-27-87599188
Country
China
ProdList
1493
Advantage
55
Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Fax
(86) 21-58955996
Email
info@chemexpress.com
Country
China
ProdList
7552
Advantage
61
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 13167063860
Fax
021-50323701
Email
anhua.mao@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
Nanjing Dulai Biotechnology Co., Ltd.
Tel
025-846993838003-8003 18013301590
Fax
025-84699383-8003
Email
njduly@126.com
Country
China
ProdList
3249
Advantage
55
AdooQ BioScience, LLC
Tel
+1 (866) 930-6790
Fax
+1 (866) 333-9607
Email
info@adooq.com
Country
United States
ProdList
2782
Advantage
58

729607-74-3, BMS707035Related Search:

Acetanilide 4-Aminodiphenylamine Dapagliflozin GSK1349572 Saracatinib Raltegravir MK-2048 Elvitegravir

  • BMS707035
  • CS-455
  • BMS 707035;BMS707035
  • 2-(1,1-DIOXOTHIAZINAN-2-YL)-N-[(4-FLUOROPHENYL)METHYL]-5-HYDROXY-1-METHYL-6-OXOPYRIMIDINE-4-CARBOXAMIDE
  • N-[(4-Fluorophenyl)methyl]-1,6-dihydro-5-hydroxy-1-methyl-6-oxo-2-(tetrahydro-1,1-dioxido-2H-1,2-thiazin-2-yl)-4-pyrimidinecarboxamide
  • 4-Pyrimidinecarboxamide, N-[(4-fluorophenyl)methyl]-1,6-dihydro-5-hydroxy-1-methyl-6-oxo-2-(tetrahydro-1,1-dioxido-2H-1,2-thiazin
  • 4-Pyrimidinecarboxamide, N-[(4-fluorophenyl)methyl]-1,6-dihydro-5-hydroxy-1-methyl-6-oxo-2-(tetrahydro-1,1-dioxido-2H-1,2-thiazin-2-yl)-
  • BMS707035 USP/EP/BP
  • 2-(1,1-Dioxido-1,2-thiazinan-2-yl)-N-(4-fluorobenzyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidine-4-carboxamide
  • BMS 707035,HIV-1 integrase strand transfer,HIV,Human immunodeficiency virus,antiviral,BMS707035,phamacokinetics,HIV Integrase,BMS-707035,CYP,inhibit,strand transfer,Inhibitor
  • BMS-707035, 10 mM in DMSO
  • 2-(4-((4-fluorobenzyl)carbamoyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)-1l4,2-thiazinane-1,1-bis(olate)
  • 729607-74-3
  • C17H19FN4O5S
  • Inhibitors
  • Inhibitor