ChemicalBook > CAS DataBase List > MK-2048
MK-2048
- Product Name
- MK-2048
- CAS No.
- 869901-69-9
- Chemical Name
- MK-2048
- Synonyms
- CS-1529;MK-2048 MK2048;MK-2048 USP/EP/BP;(S)-2-(3-chloro-4-fluorobenzyl)-8-ethyl-10-hydroxy-N,6-diMethyl-1,9-dioxo-1,2,6,7,8,9-hexahydropyrazino[1',2':1,5]pyrrolo[2,3-d]pyridazine-4-carboxaMide;(6S)-2-[(3-Chloro-4-fluorophenyl)methyl]-8-ethyl-1,2,6,7,8,9-hexahydro-10-hydroxy-N,6-dimethyl-1,9-dioxopyrazino[1',2':1,5]pyrrolo[2,3-d]pyridazine-4-carboxamide;Pyrazino[1',2':1,5]pyrrolo[2,3-d]pyridazine-4-carboxamide, 2-[(3-chloro-4-fluorophenyl)methyl]-8-ethyl-1,2,6,7,8,9-hexahydro-10-hydroxy-N,6-dimethyl-1,9-dioxo-, (6S)-
- CBNumber
- CB42616027
- Molecular Formula
- C21H21ClFN5O4
- Formula Weight
- 461.87
- MOL File
- 869901-69-9.mol
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MK-2048 Property
- Density
- 1.55
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO > 10 mM
- form
- Powder
- pka
- 6.30±0.40(Predicted)
- color
- Light yellow to yellow
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N-Bromosuccinimide Price
TRC
- Product number
- M425030
- Product name
- MK-2048
- Packaging
- 10mg
- Price
- $350
- Updated
- 2021/12/16
TRC
- Product number
- M425030
- Product name
- MK-2048
- Packaging
- 5mg
- Price
- $225
- Updated
- 2021/12/16
ApexBio Technology
- Product number
- A4072
- Product name
- (6S)-2-[(3-chloro-4-fluorophenyl)methyl]-8-ethyl-10-hydroxy-N,6-dimethyl-1,9-dioxo-6,7-dihydropyrazino[5,6]pyrrolo[1,3-b]pyridazine-4-carboxamide
- Packaging
- 10mg
- Price
- $260
- Updated
- 2021/12/16
ApexBio Technology
- Product number
- A4072
- Product name
- (6S)-2-[(3-chloro-4-fluorophenyl)methyl]-8-ethyl-10-hydroxy-N,6-dimethyl-1,9-dioxo-6,7-dihydropyrazino[5,6]pyrrolo[1,3-b]pyridazine-4-carboxamide
- Packaging
- 10mM(in 1mL DMSO)
- Price
- $350
- Updated
- 2021/12/16
ApexBio Technology
- Product number
- A4072
- Product name
- (6S)-2-[(3-chloro-4-fluorophenyl)methyl]-8-ethyl-10-hydroxy-N,6-dimethyl-1,9-dioxo-6,7-dihydropyrazino[5,6]pyrrolo[1,3-b]pyridazine-4-carboxamide
- Packaging
- 5mg
- Price
- $190
- Updated
- 2021/12/16
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MK-2048 Chemical Properties,Usage,Production
Uses
MK-2048 represents a prototype second generation integrase strand transfer inhibitor (INSTI), it was developed with the goal of retaining activity against viruses containing mutations assiciated with resistance of first-generation INSTIs, raltegravir (R100312). MK-2048 exhibits inhibitory activity towards HIV integrase and towards HIV replication. It is four times more effective in inhibiting HIV enzyme integrase than the first generation inhibitor, raltegravir.
target
subtype B integrase
MK-2048 Preparation Products And Raw materials
Raw materials
Preparation Products
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MK-2048 Suppliers
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