2-[(4-Acetylphenyl)azo]-2-(3,4-dihydro-3,3-diMethyl-1(2H)- isoquinolinylidene)acetaMide
- Product Name
- 2-[(4-Acetylphenyl)azo]-2-(3,4-dihydro-3,3-diMethyl-1(2H)- isoquinolinylidene)acetaMide
- CAS No.
- 331001-62-8
- Chemical Name
- 2-[(4-Acetylphenyl)azo]-2-(3,4-dihydro-3,3-diMethyl-1(2H)- isoquinolinylidene)acetaMide
- Synonyms
- IQ 1; IQ1;IQ-1 - CAS 331001-62-8 - Calbiochem;2-[(4-Acetylphenyl)hydrazinylidene]-2-(3,3-dimethyl-4H-isoquinolin-1-yl)acetamide;2-[(4-Acetylphenyl)azo]-2-(3,4-dihydro-3,3-diMethyl-1(2H)- isoquinolinylidene)acetaMide;2-[2-(4-Acetylphenyl)diazenyl]-2-(3,4-dihydro-3,3-diMethyl-1(2H)-isoquinolinylidene)-acetaMide;AcetaMide, 2-[2-(4-acetylphenyl)diazenyl]-2-(3,4-dihydro-3,3-diMethyl-1(2H)-isoquinolinylidene)-;spontaneous differentiation,expansion,β-catenin/p300,β-catenin/CBP,inhibit,P19 cells,Wnt,Inhibitor,PR72/130,IQ 1,ESCs
- CBNumber
- CB42622729
- Molecular Formula
- C21H22N4O2
- Formula Weight
- 362.42
- MOL File
- 331001-62-8.mol
2-[(4-Acetylphenyl)azo]-2-(3,4-dihydro-3,3-diMethyl-1(2H)- isoquinolinylidene)acetaMide Property
- Boiling point:
- 591.2±50.0 °C(Predicted)
- Density
- 1.23±0.1 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- DMF: 30 mg/ml; DMSO: 25 mg/ml; Ethanol: 10 mg/ml
- form
- powder
- pka
- 15.71±0.50(Predicted)
- color
- yellow to orange
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- SML1147
- Product name
- IQ-1
- Purity
- ≥95% (HPLC)
- Packaging
- 5mg
- Price
- $106
- Updated
- 2024/03/01
- Product number
- 412400
- Product name
- IQ-1 - CAS 331001-62-8 - Calbiochem<br />A cell-permeable tetrahydroisoquinolinylidene compound that modulates Wnt/β-catenin signaling by targeting the PR72/130 subunit of PP2A and thereby blocking PP2A/Nkd complex formation.
- Packaging
- 10mg
- Price
- $318
- Updated
- 2024/03/01
- Product number
- 16153
- Product name
- IQ-1
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $106
- Updated
- 2024/03/01
- Product number
- 16153
- Product name
- IQ-1
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $178
- Updated
- 2024/03/01
- Product number
- SML1147
- Product name
- IQ-1
- Purity
- ≥95% (HPLC)
- Packaging
- 25mg
- Price
- $370
- Updated
- 2022/05/15
2-[(4-Acetylphenyl)azo]-2-(3,4-dihydro-3,3-diMethyl-1(2H)- isoquinolinylidene)acetaMide Chemical Properties,Usage,Production
Uses
IQ 1 disrupts Wnt signaling. IQ-1 in conjunction with Wnt3a has been shown to be sufficient to maintain murine embryonic stem cell proliferation in the absence of serum. Binds to the PR72/PR130 subunit of protein phosphatase PP2A preventing β-catenin from switching co-activator usage from CBP to p300 leading to an increase in β-catenin/CBP-driven transcription at the expense of β-catenin/p300-driven transcription.
Definition
ChEBI: 2-[(4-acetylphenyl)hydrazinylidene]-2-(3,3-dimethyl-4H-isoquinolin-1-yl)acetamide is an aromatic ketone.
storage
-20°C
2-[(4-Acetylphenyl)azo]-2-(3,4-dihydro-3,3-diMethyl-1(2H)- isoquinolinylidene)acetaMide Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-[(4-Acetylphenyl)azo]-2-(3,4-dihydro-3,3-diMethyl-1(2H)- isoquinolinylidene)acetaMide manufacturers
- Product
- 2-[(4-Acetylphenyl)azo]-2-(3,4-dihydro-3,3-diMethyl-1(2H)- isoquinolinylidene)acetaMide 331001-62-8
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99.99%
- Supply Ability
- 200kg
- Release date
- 2019-12-20