2-[(4-Acetylphenyl)azo]-2-(3,4-dihydro-3,3-diMethyl-1(2H)- isoquinolinylidene)acetaMide

Product Name: 2-[(4-Acetylphenyl)azo]-2-(3,4-dihydro-3,3-diMethyl-1(2H)- isoquinolinylidene)acetaMide
CAS No.: 331001-62-8
Chemical Name: 2-[(4-Acetylphenyl)azo]-2-(3,4-dihydro-3,3-diMethyl-1(2H)- isoquinolinylidene)acetaMide
Synonyms: IQ 1; IQ1;IQ-1 - CAS 331001-62-8 - Calbiochem;2-[(4-Acetylphenyl)hydrazinylidene]-2-(3,3-dimethyl-4H-isoquinolin-1-yl)acetamide;2-[(4-Acetylphenyl)azo]-2-(3,4-dihydro-3,3-diMethyl-1(2H)- isoquinolinylidene)acetaMide;2-((4-Acetylphenyl)diazenyl)-2-(3,3-dimethyl-3,4-dihydroisoquinolin-1(2H)-ylidene)acetamide;2-[2-(4-Acetylphenyl)diazenyl]-2-(3,4-dihydro-3,3-diMethyl-1(2H)-isoquinolinylidene)-acetaMide;AcetaMide, 2-[2-(4-acetylphenyl)diazenyl]-2-(3,4-dihydro-3,3-diMethyl-1(2H)-isoquinolinylidene)-;spontaneous differentiation,expansion,β-catenin/p300,β-catenin/CBP,inhibit,P19 cells,Wnt,Inhibitor,PR72/130,IQ 1,ESCs
CBNumber: CB42622729
Molecular Formula: C21H22N4O2
Formula Weight: 362.42
MOL File: 331001-62-8.mol

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2-[(4-Acetylphenyl)azo]-2-(3,4-dihydro-3,3-diMethyl-1(2H)- isoquinolinylidene)acetaMide Property

Boiling point:: 591.2±50.0 °C(Predicted)
Density: 1.23±0.1 g/cm3(Predicted)
storage temp.: -20°C
solubility: DMF: 30 mg/ml; DMSO: 25 mg/ml; Ethanol: 10 mg/ml
form: powder
pka: 15.71±0.50(Predicted)
color: yellow to orange

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML1147
Product name: IQ-1
Purity: ≥95% (HPLC)
Packaging: 5mg
Price: $106
Updated: 2024/03/01

Sigma-Aldrich

Product number: 412400
Product name: IQ-1 - CAS 331001-62-8 - Calbiochem<br />A cell-permeable tetrahydroisoquinolinylidene compound that modulates Wnt/β-catenin signaling by targeting the PR72/130 subunit of PP2A and thereby blocking PP2A/Nkd complex formation.
Packaging: 10mg
Price: $318
Updated: 2024/03/01

Cayman Chemical

Product number: 16153
Product name: IQ-1
Purity: ≥98%
Packaging: 5mg
Price: $106
Updated: 2024/03/01

Cayman Chemical

Product number: 16153
Product name: IQ-1
Purity: ≥98%
Packaging: 10mg
Price: $178
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML1147
Product name: IQ-1
Purity: ≥95% (HPLC)
Packaging: 25mg
Price: $370
Updated: 2022/05/15

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2-[(4-Acetylphenyl)azo]-2-(3,4-dihydro-3,3-diMethyl-1(2H)- isoquinolinylidene)acetaMide Chemical Properties,Usage,Production

Uses

IQ 1 disrupts Wnt signaling. IQ-1 in conjunction with Wnt3a has been shown to be sufficient to maintain murine embryonic stem cell proliferation in the absence of serum. Binds to the PR72/PR130 subunit of protein phosphatase PP2A preventing β-catenin from switching co-activator usage from CBP to p300 leading to an increase in β-catenin/CBP-driven transcription at the expense of β-catenin/p300-driven transcription.

Definition

ChEBI: 2-[(4-acetylphenyl)hydrazinylidene]-2-(3,3-dimethyl-4H-isoquinolin-1-yl)acetamide is an aromatic ketone.

storage

-20°C

2-[(4-Acetylphenyl)azo]-2-(3,4-dihydro-3,3-diMethyl-1(2H)- isoquinolinylidene)acetaMide Preparation Products And Raw materials

Raw materials

Preparation Products

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2-[(4-Acetylphenyl)azo]-2-(3,4-dihydro-3,3-diMethyl-1(2H)- isoquinolinylidene)acetaMide Suppliers

China 51 India 1 United Kingdom 1 United States 10 Global 63

Tocris Bioscience

Tel: --
Fax: --
Email: customerservice@tocris.co.uk
Country: United Kingdom
ProdList: 5726
Advantage: 77

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View Lastest Price from 2-[(4-Acetylphenyl)azo]-2-(3,4-dihydro-3,3-diMethyl-1(2H)- isoquinolinylidene)acetaMide manufacturers

Career Henan Chemical Co

Product: 2-[(4-Acetylphenyl)azo]-2-(3,4-dihydro-3,3-diMethyl-1(2H)- isoquinolinylidene)acetaMide 331001-62-8
Price: US $1.00/g
Min. Order: 1g
Purity: 99.99%
Supply Ability: 200kg
Release date: 2019-12-20

331001-62-8, 2-[(4-Acetylphenyl)azo]-2-(3,4-dihydro-3,3-diMethyl-1(2H)- isoquinolinylidene)acetaMideRelated Search:

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2-[2-(4-Acetylphenyl)diazenyl]-2-(3,4-dihydro-3,3-diMethyl-1(2H)-isoquinolinylidene)-acetaMide

IQ-1 - CAS 331001-62-8 - Calbiochem

2-[(4-Acetylphenyl)hydrazinylidene]-2-(3,3-dimethyl-4H-isoquinolin-1-yl)acetamide

IQ 1; IQ1

spontaneous differentiation,expansion,β-catenin/p300,β-catenin/CBP,inhibit,P19 cells,Wnt,Inhibitor,PR72/130,IQ 1,ESCs

2-((4-Acetylphenyl)diazenyl)-2-(3,3-dimethyl-3,4-dihydroisoquinolin-1(2H)-ylidene)acetamide

331001-62-8

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