3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-diMethylpyrido[2,3-d]pyriMidine-2,4,7(1H,3H,8H)-trione

Product Name: 3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-diMethylpyrido[2,3-d]pyriMidine-2,4,7(1H,3H,8H)-trione
CAS No.: 871700-24-2
Chemical Name: 3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-diMethylpyrido[2,3-d]pyriMidine-2,4,7(1H,3H,8H)-trione
Synonyms: Trametinib INT;TrametinibImpurity12;Trametinib Impurity 4;Trametinib Impurity 05;GSK1120212 Intermediate 7;cyclopropylthiadiazolamine;3-Cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-dimethylpyrido[2,3-d]pyrimidine-2,4,7(1H;3-cyclopropyl-1-(2-fluoro-4-iodo-phenyl)-5-hydroxy-6,8-dimethyl-pyrido[2,3-d]pyrimidine-2,4,7-trione;3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-diMethylpyrido[2,3-d]pyriMidine-2,4,7(1H,3H,8H;3-Cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-dimethyl-1H,8H-pyrido[2,3-d]pyrimidine-2,4,7-trione
CBNumber: CB42623933
Molecular Formula: C18H15FIN3O4
Formula Weight: 483.23
MOL File: 871700-24-2.mol

More

Less

3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-diMethylpyrido[2,3-d]pyriMidine-2,4,7(1H,3H,8H)-trione Property

Boiling point:: 518.2±60.0 °C(Predicted)
Density: 1.94±0.1 g/cm3(Predicted)
storage temp.: 2-8°C(protect from light)
solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
pka: 4.50±1.00(Predicted)
color: White to Off-White
InChI: InChI=1S/C18H15FIN3O4/c1-8-14(24)13-15(21(2)16(8)25)23(12-6-3-9(20)7-11(12)19)18(27)22(17(13)26)10-4-5-10/h3,6-7,10,24H,4-5H2,1-2H3
InChIKey: MHHFXMZMCYWCJQ-UHFFFAOYSA-N
SMILES: C1(=O)N(C2CC2)C(=O)C2C(O)=C(C)C(=O)N(C)C=2N1C1=CC=C(I)C=C1F

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

ChemScene

Product number: CS-M0422
Product name: 3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-dimethylpyrido[2,3-d]pyrimidine-2,4,7(1H,3H,8H)-trione
Packaging: 250mg
Price: $70
Updated: 2021/12/16

AK Scientific

Product number: 6078DP
Product name: CID59717004
Packaging: 100mg
Price: $124
Updated: 2021/12/16

AK Scientific

Product number: 6078DP
Product name: CID59717004
Packaging: 250mg
Price: $157
Updated: 2021/12/16

ChemScene

Product number: CS-M0422
Product name: 3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-dimethylpyrido[2,3-d]pyrimidine-2,4,7(1H,3H,8H)-trione
Packaging: 1g
Price: $170
Updated: 2021/12/16

ChemScene

Product number: CS-M0422
Product name: 3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-dimethylpyrido[2,3-d]pyrimidine-2,4,7(1H,3H,8H)-trione
Packaging: 5g
Price: $521
Updated: 2021/12/16

More

Less

3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-diMethylpyrido[2,3-d]pyriMidine-2,4,7(1H,3H,8H)-trione Chemical Properties,Usage,Production

Uses

3-Cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-dimethylpyrido[2,3-d]pyrimidine-2,4,7-trione is used for treatment of cancer and rheumatic diseases

3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-diMethylpyrido[2,3-d]pyriMidine-2,4,7(1H,3H,8H)-trione Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-diMethylpyrido[2,3-d]pyriMidine-2,4,7(1H,3H,8H)-trione Suppliers

China 92 India 1 United States 4 Global 97

Shanghai YuZn Pharm. Technology Co.,Ltd.

Tel: 15921286451; 15921286451
Email: 2010681527@qq.com
Country: China
ProdList: 5181
Advantage: 58

Guangzhou Anyanren Pharmaceutical Technology Co., Ltd.

Tel: 18028661570
Email: 2412659056@qq.com
Country: China
ProdList: 291
Advantage: 58

Tianjin Leno Bede Technology Co. LTD

Tel: 022-87899851 18522914591
Email: hzauzhangchao@163.com
Country: China
ProdList: 95
Advantage: 58

Wuhan Dingtong Pharmaceutical Co., Ltd

Tel: 183-27179646 18327179646
Fax: 027-59207795
Email: 18327179646@163.com
Country: China
ProdList: 1985
Advantage: 58

Jiangxi Puxin Biotechnology Co., Ltd

Tel: 15867635987 15867635987;
Email: jasonhu09@163.com
Country: China
ProdList: 796
Advantage: 58

TIANJIN PHARMACN MEDICAL TECHNOLOGY CO.,LTD.

Tel: 022-60189726 18812034280
Fax: 86-22-60979672
Email: 188120342808@163.com
Country: China
ProdList: 142
Advantage: 61

Tianjin Branch Chong pharmaceutical intermediates Co., Ltd.

Tel: 022-60116533 13207668525
Fax: 022-60979672
Email: saleskc@scipharmacn.com
Country: China
ProdList: 551
Advantage: 58

Tianjin Famoxi Biopharmaceutical Technology Co., Ltd

Tel: 18522868115; 18522868115
Email: yuqingliu@bio-pharmacn.com
Country: China
ProdList: 122
Advantage: 58

S.Z. PhyStandard Bio-Tech. Co., Ltd.

Tel: 0755-4000505016 13380397412
Fax: 0755 28094224
Email: 3001272453@qq.com
Country: China
ProdList: 5158
Advantage: 50

Shenzhen HwaGen Pharmaceutical Co.,Ltd

Tel: 18927334162 18927334162;17722620669
Email: sales1@rafflespt.com
Country: China
ProdList: 292
Advantage: 58

More

Less

View Lastest Price from 3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-diMethylpyrido[2,3-d]pyriMidine-2,4,7(1H,3H,8H)-trione manufacturers

Hong Kong Tiansheng New Material Trading Co., Ltd

Product: cyclopropylthiadiazolamine 871700-24-2
Price: US $16.90/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1KG
Release date: 2021-09-24

Hong Kong Tiansheng New Material Trading Co., Ltd

Product: 3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-dimethylpyrido[2,3-d]pyrimidine-2,4,7(1H,3H,8H)-trione 871700-24-2
Price: US $16.90/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10kg
Release date: 2021-09-24

Hong Kong Tiansheng New Material Trading Co., Ltd

Product: 3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-dimethylpyrido[2,3-d]pyrimidine-2,4,7(1H,3H,8H)-trione 871700-24-2
Price: US $16.90/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1
Release date: 2022-03-30

871700-24-2, 3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-diMethylpyrido[2,3-d]pyriMidine-2,4,7(1H,3H,8H)-trioneRelated Search:

3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-6-(MethylaMino)pyriMidine-2,4(1H,3H)-dione 3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-6,8-dimethyl-2,4,7-trioxo-1,2,3,4,7,8-hexahydropyrido[2,3-d]pyrimidin-5-yl trifluoromethanesulfonate Sunitinib Lapatinib LOXO-101

3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-diMethylpyrido[2,3-d]pyriMidine-2,4,7(1H,3H,8H)-trione

3-Cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-dimethyl-1H,8H-pyrido[2,3-d]pyrimidine-2,4,7-trione

3-Cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-dimethylpyrido[2,3-d]pyrimidine-2,4,7(1H

Pyrido[2,3-d]pyrimidine-2,4,7(1H,3H,8H)-trione, 3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-dimethyl-

cyclopropylthiadiazolamine

3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-diMethylpyrido[2,3-d]pyriMidine-2,4,7(1H,3H,8H

Trametinib INT

Trametinib Impurity 4

TrametinibImpurity12

3-cyclopropyl-1-(2-fluoro-4-iodo-phenyl)-5-hydroxy-6,8-dimethyl-pyrido[2,3-d]pyrimidine-2,4,7-trione

GSK1120212 Intermediate 7

Trametinib Impurity 05

3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-diMethylpyrido[2,3-d]pyriMidine-2,4,7(1H,3H,8H)-trio

871700-24-2

C18H15FIN3O4

Research