ChemicalBook > CAS DataBase List > 3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-diMethylpyrido[2,3-d]pyriMidine-2,4,7(1H,3H,8H)-trione
3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-diMethylpyrido[2,3-d]pyriMidine-2,4,7(1H,3H,8H)-trione
- Product Name
- 3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-diMethylpyrido[2,3-d]pyriMidine-2,4,7(1H,3H,8H)-trione
- CAS No.
- 871700-24-2
- Chemical Name
- 3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-diMethylpyrido[2,3-d]pyriMidine-2,4,7(1H,3H,8H)-trione
- Synonyms
- Trametinib INT;TrametinibImpurity12;Trametinib Impurity 4;cyclopropylthiadiazolamine;3-Cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-dimethylpyrido[2,3-d]pyrimidine-2,4,7(1H;3-cyclopropyl-1-(2-fluoro-4-iodo-phenyl)-5-hydroxy-6,8-dimethyl-pyrido[2,3-d]pyrimidine-2,4,7-trione;3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-diMethylpyrido[2,3-d]pyriMidine-2,4,7(1H,3H,8H;3-Cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-dimethyl-1H,8H-pyrido[2,3-d]pyrimidine-2,4,7-trione;3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-diMethylpyrido[2,3-d]pyriMidine-2,4,7(1H,3H,8H)-trione;Pyrido[2,3-d]pyrimidine-2,4,7(1H,3H,8H)-trione, 3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-dimethyl-
- CBNumber
- CB42623933
- Molecular Formula
- C18H15FIN3O4
- Formula Weight
- 483.23
- MOL File
- 871700-24-2.mol
More
Less
3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-diMethylpyrido[2,3-d]pyriMidine-2,4,7(1H,3H,8H)-trione Property
- Boiling point:
- 518.2±60.0 °C(Predicted)
- Density
- 1.94±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C(protect from light)
- solubility
- DMSO (Slightly), Methanol (Slightly)
- pka
- 4.50±1.00(Predicted)
- form
- Solid
- color
- White to Off-White
More
Less
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
More
Less
N-Bromosuccinimide Price
ChemScene
- Product number
- CS-M0422
- Product name
- 3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-dimethylpyrido[2,3-d]pyrimidine-2,4,7(1H,3H,8H)-trione
- Packaging
- 250mg
- Price
- $70
- Updated
- 2021/12/16
AK Scientific
- Product number
- 6078DP
- Product name
- CID59717004
- Packaging
- 100mg
- Price
- $124
- Updated
- 2021/12/16
AK Scientific
- Product number
- 6078DP
- Product name
- CID59717004
- Packaging
- 250mg
- Price
- $157
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-M0422
- Product name
- 3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-dimethylpyrido[2,3-d]pyrimidine-2,4,7(1H,3H,8H)-trione
- Packaging
- 1g
- Price
- $170
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-M0422
- Product name
- 3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-dimethylpyrido[2,3-d]pyrimidine-2,4,7(1H,3H,8H)-trione
- Packaging
- 5g
- Price
- $521
- Updated
- 2021/12/16
More
Less
3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-diMethylpyrido[2,3-d]pyriMidine-2,4,7(1H,3H,8H)-trione Chemical Properties,Usage,Production
Uses
3-Cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-dimethylpyrido[2,3-d]pyrimidine-2,4,7-trione is used for treatment of cancer and rheumatic diseases
3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-diMethylpyrido[2,3-d]pyriMidine-2,4,7(1H,3H,8H)-trione Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-diMethylpyrido[2,3-d]pyriMidine-2,4,7(1H,3H,8H)-trione Suppliers
- Tel
- 18028661570
- 2412659056@qq.com
- Country
- China
- ProdList
- 314
- Advantage
- 58
- Tel
- 022-87899851 18522914591
- hzauzhangchao@163.com
- Country
- China
- ProdList
- 85
- Advantage
- 58
- Tel
- 022-60116533 13207668525
- Fax
- 022-60979672
- saleskc@scipharmacn.com
- Country
- China
- ProdList
- 684
- Advantage
- 58
- Tel
- 18927339850
- Fax
- 0752-5319394
- xiaodong.shi@rafflespt.com
- Country
- China
- ProdList
- 237
- Advantage
- 58
- Tel
- 021-34666753 13311639313
- Fax
- +86-21-34979012
- info@shyrchem.com
- Country
- China
- ProdList
- 571
- Advantage
- 55
- Tel
- 021-58950125
- Fax
- (86) 21-58955996
- info@chemexpress.com
- Country
- China
- ProdList
- 7552
- Advantage
- 61
- Tel
- 400-164-7117 13681763483
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 41462
- Advantage
- 60
- Tel
- 18112588827
- sales4@sepharm.com.cn
- Country
- China
- ProdList
- 307
- Advantage
- 60
- Tel
- +86-2332782371 +86-18120098618
- sales@adobechem.com
- Country
- China
- ProdList
- 1250
- Advantage
- 50
- Tel
- Fax
- -
- eric_feng1954@126.com
- Country
- China
- ProdList
- 9248
- Advantage
- 55
More
Less
View Lastest Price from 3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-diMethylpyrido[2,3-d]pyriMidine-2,4,7(1H,3H,8H)-trione manufacturers
Hong Kong Tiansheng New Material Trading Co., Ltd
- Product
- cyclopropylthiadiazolamine 871700-24-2
- Price
- US $16.90/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1KG
- Release date
- 2021-09-24
Hong Kong Tiansheng New Material Trading Co., Ltd
- Product
- 3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-dimethylpyrido[2,3-d]pyrimidine-2,4,7(1H,3H,8H)-trione 871700-24-2
- Price
- US $16.90/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10kg
- Release date
- 2021-09-24
Hong Kong Tiansheng New Material Trading Co., Ltd
- Product
- 3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-dimethylpyrido[2,3-d]pyrimidine-2,4,7(1H,3H,8H)-trione 871700-24-2
- Price
- US $16.90/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1
- Release date
- 2022-03-30
871700-24-2, 3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-diMethylpyrido[2,3-d]pyriMidine-2,4,7(1H,3H,8H)-trioneRelated Search:
3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-6-(MethylaMino)pyriMidine-2,4(1H,3H)-dione
3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-6,8-dimethyl-2,4,7-trioxo-1,2,3,4,7,8-hexahydropyrido[2,3-d]pyrimidin-5-yl trifluoromethanesulfonate
Sunitinib
Lapatinib
LOXO-101