ChemicalBook > CAS DataBase List > AM095

AM095

Product Name
AM095
CAS No.
1228690-36-5
Chemical Name
AM095
Synonyms
CS-1624;AM095 (free acid);AM-095 (free base);AM 095 (parent compound);AM 095;AM-095;AM-095 FREE ACID;AM 095 FREE ACID;[4'-[3-Methyl-4-[[[((R)-1-phenylethyl)oxy]carbonyl]amino]isoxazol-5-yl]biphenyl-4-yl]acetic acid;2-[4-[4-[3-methyl-4-[[(1r)-1-phenylethoxy]carbonylamino]-1,2-oxazol-5-yl]phenyl]phenyl]acetic Acid;[1,1'-Biphenyl]-4-acetic acid, 4'-[3-methyl-4-[[[(1R)-1-phenylethoxy]carbonyl]amino]-5-isoxazolyl]-;(R)-2-(4'-(3-Methyl-4-(((1-phenylethoxy)carbonyl)amino)isoxazol-5-yl)-[1,1'-biphenyl]-4-yl)acetic acid;AM 095,Inhibitor,AM095 free acid,AM-095 free acid,inhibit,AM095,Lysophospholipid Receptor,AM-095,LPL Receptor
CBNumber
CB42624905
Molecular Formula
C27H24N2O5
Formula Weight
456.49
MOL File
1228690-36-5.mol
More
Less

AM095 Property

Boiling point:
641.9±55.0 °C(Predicted)
Density 
1.278±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
insoluble in EtOH; ≥42 mg/mL in DMSO; ≥8.12 mg/mL in H2O with ultrasonic
form 
Powder
pka
4.21±0.10(Predicted)
color 
White to off-white
More
Less

Safety

HS Code 
2934999090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

More
Less

N-Bromosuccinimide Price

Cayman Chemical
Product number
22141
Product name
AM095
Purity
≥98%
Packaging
5mg
Price
$81
Updated
2024/03/01
Cayman Chemical
Product number
22141
Product name
AM095
Purity
≥98%
Packaging
10mg
Price
$152
Updated
2024/03/01
Cayman Chemical
Product number
22141
Product name
AM095
Purity
≥98%
Packaging
25mg
Price
$356
Updated
2024/03/01
ApexBio Technology
Product number
A3167
Product name
AM-095freebase
Packaging
50mg
Price
$488
Updated
2021/12/16
ChemScene
Product number
CS-1129
Product name
AM095freeacid
Purity
99.28%
Packaging
50mg
Price
$540
Updated
2021/12/16
More
Less

AM095 Chemical Properties,Usage,Production

Biological Activity

am095 is a novel, potent and orally bioavailable antagonist of lysophosphatidic acid type 1 receptor (lpa1) with ic50 values of 0.73 and 0.98 μm for mouse or recombinant human lpa1, respectively [1].

in vitro

am095 has shown to inhibit lpa1-induced chemotaxis of both mouse lpa1/cho cells and human a2058 melanoma cells with ic50 values of 0.78 μm and 0.23μm [1].

in vivo

am095 could dose-dependently block lpa-induced histamine release with an ed50 value of 8.3 mg/kg in mice. additionally, am095 has been revealed to remarkably reduce the balf collagen and protein with an ed50 value of 10 mg/kg in lungs. am095 has also shown to decrease both macrophage and lymphocyte infiltration induced by bleomycin in mice [1].

target

LPA1 receptor

References

[1] swaney js1, chapman c, correa ld, stebbins kj, broadhead ar, bain g, santini am, darlington j, king cd, baccei cs, lee c, parr ta, roppe jr, seiders tj, ziff j, prasit p, hutchinson jh, evans jf, lorrain ds. pharmacokinetic and pharmacodynamic characterization of an oral lysophosphatidic acid type 1 receptor-selective antagonist. j pharmacol exp ther. 2011 mar;336(3):693-700.

AM095 Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

AM095 Suppliers

China 60 India 1 The Netherlands 1 United States 13 Global 75
Kaixin Chemical (Hong Kong) Limited
Tel
010-88886666-01 13112345678
Fax
CDXH21@126.com
Email
loyson@tcypharm.com
Country
China
ProdList
595
Advantage
55
Shanghai Boyle Chemical Co., Ltd.
Tel
Fax
86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2922
Advantage
55
Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Fax
(86) 21-58955996
Email
info@chemexpress.com
Country
China
ProdList
7552
Advantage
61
Shanghai CanSpecsci Instrument Co., Ltd.
Tel
400-6087598 15021221957
Fax
4006087598-8012
Email
order@canspecsci.com
Country
China
ProdList
2045
Advantage
56
Shandong Juntai Pharmaceutical Co., LTD.
Tel
18615688519
Fax
0531-66958526
Email
sales@h2opharm.com
Country
China
ProdList
162
Advantage
55
AdooQ Bioscience CHINA
Tel
025-58849295 18951903616;
Fax
025-68650336
Email
info@adooq.cn
Country
China
ProdList
2990
Advantage
60
Shanghai JiYi Biotechnology Co. Ltd.
Tel
13621943973
Fax
-
Email
sales@shjiyipharmatech.com
Country
China
ProdList
1166
Advantage
55
LETOPHARM LIMITED
Tel
+86-21-5821 5861
Fax
+86-21-5106 2861
Email
sales@letopharm.com
Country
China
ProdList
2384
Advantage
58
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696，15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4573
Advantage
55
Suzhou Chenke Biotech Co., Ltd.
Tel
18662408853 18662408853
Email
2120408911@qq.com
Country
China
ProdList
898
Advantage
55
SPIRO PHARMA
Tel
Fax
-
Email
eric_feng1954@126.com
Country
China
ProdList
9248
Advantage
55
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9806
Advantage
58
Jinan SanZhi Pharmaceutical Technology Co., Ltd.
Tel
15053191807
Fax
-
Email
sales_sanzhi@163.com
Country
China
ProdList
286
Advantage
55
Guangzhou QiYun Biotechnology Co., Ltd.
Tel
020-61288194 61288195
Fax
020-61288700
Email
505721671@qq.com
Country
China
ProdList
3866
Advantage
58
Shanghai Changyan Chem & Tech Co., Ltd.
Tel
021-20242659 18930833303
Fax
+86 (21) 2024-2659
Email
Sales@changyanchem.cn
Country
China
ProdList
5010
Advantage
55
ShangHai Biochempartner Co.,Ltd
Tel
177-54423994 17754423994
Fax
QQ:2853530913
Email
2853530910@QQ.com
Country
China
ProdList
8011
Advantage
62
Shanghai Chaolan Chemical Technology Center
Tel
021-QQ：65489617 15618227136
Fax
21-5161 9052
Email
Sales@ATKchemical.com
Country
China
ProdList
7295
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Medi-tech Bioscientific Co., Ltd.
Tel
0519-83246372 13585352506
Fax
0519-83246372
Country
China
ProdList
1844
Advantage
58
Chuzhou KeMail Chemical Technology Co., Ltd
Tel
0550-5196001 15000891977
Fax
0550-5196001
Email
wj520wjxby@126.com
Country
China
ProdList
1925
Advantage
55
Jinan Weicheng Pharmaceutical Technology Co., Ltd
Tel
0531-68656072 15562569859
Fax
0531-68656072
Email
2921569326@qq.com
Country
China
ProdList
57
Advantage
55
Shanghai Biopharmaleader Co., Ltd.
Tel
+86 18721201413
Fax
+86 (21) 5775-8967
Email
sales@biopharmaleader.com
Country
China
ProdList
1720
Advantage
58
Angel Pharmatech, Ltd.
Tel
17317130613
Fax
QQ3358272972
Email
3358272972@qq.com
Country
China
ProdList
3254
Advantage
58
Fan De(Beijing) Biotechnology Co., Ltd.
Tel
15911056312
Email
liming@bio-fount.com
Country
China
ProdList
9729
Advantage
58
Aishilun biotechnology (Shanghai) co., LTD
Tel
021-50676523 18019098996
Email
info@acelybio.com
Country
China
ProdList
3960
Advantage
58
Zhejiang J&C Biological Technology Co.,Limited
Tel
+1-2135480471 +1-2135480471
Email
sales@sarms4muscle.com
Country
China
ProdList
10473
Advantage
58
DC Chemicals
Tel
021-58447131 13564518121
Email
sales@dcchemicals.com
Country
China
ProdList
9409
Advantage
58
Absin Bioscience Inc.
Tel
021-38015121 15000105423
Email
wulan@absin.cn
Country
China
ProdList
24731
Advantage
58
Shanghai hongqu biomedical technology co. LTD
Tel
88888888888
Email
hongquchem@qq.com
Country
China
ProdList
5132
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing1@energy-chemical.com
Country
China
ProdList
44806
Advantage
58
Wuhan Topule
Tel
+86-02787215551 +86-19945035818
Fax
027-87215551
Email
2936752263@qq.com
Country
China
ProdList
8084
Advantage
58
cjbscvictory
Tel
13348960310 13348960310
Email
3003867561@qq.com
Country
China
ProdList
10011
Advantage
58
Changzhou Furuisi Biotechnology Co., Ltd
Tel
0519-85524369
Email
3477467573@qq.com
Country
China
ProdList
8617
Advantage
58
Abmole Bioscience Inc.
Tel
021-50967598 02150967598
Email
sales@abmole.cn
Country
China
ProdList
4494
Advantage
58
Jinan Jiuli Biotechnology Co. , Ltd.
Tel
15865264761
Email
486064515@qq.com
Country
China
ProdList
4542
Advantage
58
Jinan Cen Ben Medical Technology Co., Ltd
Tel
14793566
Email
info@cenpharm.com
Country
China
ProdList
698
Advantage
58
SINO High Goal Chemical Technology Co., Ltd.
Tel
021-57646680 18306277365
Email
guoxin@chembiobanksh.com
Country
China
ProdList
2559
Advantage
58
JinOu Biomedical (Nanjing) Co., Ltd.
Tel
13000000000
Fax
jinoupharma@163
Email
jinoupharma@163.com
Country
China
ProdList
11721
Advantage
58
ChemeGen 中国
Tel
18818260767
Fax
QQ 3610331285
Email
2625930290@qq.com
Country
China
ProdList
6973
Advantage
58
Wuhan Augda Biotechnology Co., Ltd
Tel
15071299552
Fax
QQ:262933239
Email
262933239@qq.com
Country
China
ProdList
6887
Advantage
58
Bide Pharmatech Ltd.
Tel
400-1647117 13681763483
Email
product02@bidepharm.com
Country
China
ProdList
62075
Advantage
58
InvivoChem
Tel
13549236410
Email
sales@invivochem.cn
Country
China
ProdList
6753
Advantage
58
Changzhou Bojia Biomedical Technology Co., Ltd.
Tel
2122619822
Email
czbjpharma@126.com
Country
China
ProdList
18478
Advantage
58
Wuhan Yingnuo Pharmaceutical Technology Co., Ltd.
Tel
+86-027-59232304 15387063101
Email
2881924050@qq.com
Country
China
ProdList
9959
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24644
Advantage
58
WEITIXIHAUGONG
Tel
0371-53370800 18037197114
Email
2853031799@qq.com
Country
China
ProdList
9938
Advantage
58
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
18621169109
Email
market03@meryer.com
Country
China
ProdList
27987
Advantage
58
Suzhou Haiben Pharmaceutical Co., Ltd
Tel
14760821013 13564957716
Email
1816280386@qq.com
Country
China
ProdList
7992
Advantage
58
https://hanhongsci.com/
Tel
021-54306202 18917919676
Email
info@hanhongsci.com
Country
China
ProdList
29979
Advantage
58
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd
Tel
021-59167510 18117107507
Email
vip@med-life.cn
Country
China
ProdList
4997
Advantage
58
More
Less

View Lastest Price from AM095 manufacturers

Career Henan Chemical Co
Product
AM095 1228690-36-5
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
JD 491
Release date
2019-09-01

1228690-36-5, AM095Related Search:

N,N-DIETHYLBENZAMIDE Adenosine 2-Methylindole Octadecyl methacrylate

  • AM-095 (free base)
  • AM095 (free acid)
  • [4'-[3-Methyl-4-[[[((R)-1-phenylethyl)oxy]carbonyl]amino]isoxazol-5-yl]biphenyl-4-yl]acetic acid
  • AM 095 (parent compound)
  • 2-[4-[4-[3-methyl-4-[[(1r)-1-phenylethoxy]carbonylamino]-1,2-oxazol-5-yl]phenyl]phenyl]acetic Acid
  • AM 095;AM-095;AM-095 FREE ACID;AM 095 FREE ACID
  • CS-1624
  • [1,1'-Biphenyl]-4-acetic acid, 4'-[3-methyl-4-[[[(1R)-1-phenylethoxy]carbonyl]amino]-5-isoxazolyl]-
  • AM 095,Inhibitor,AM095 free acid,AM-095 free acid,inhibit,AM095,Lysophospholipid Receptor,AM-095,LPL Receptor
  • (R)-2-(4'-(3-Methyl-4-(((1-phenylethoxy)carbonyl)amino)isoxazol-5-yl)-[1,1'-biphenyl]-4-yl)acetic acid
  • 1228690-36-5
  • 228690-36-5