11107B

Product Name: 11107B
CAS No.: 445493-23-2
Chemical Name: 11107B
Synonyms: 11107B;11107AD;PLADIENOLIDE B;SDOUORKJIJYJNW-VGQSKDSZSA-N;(4R,7R,8S,9E,11S,12S)-8-(Acetyloxy)-4,7-dihydroxy-12-[(1E,3E,5S)-6-[(2R,3R)-3-[(1R,2S)-2-hydroxy-1-methylbutyl]-2-oxiranyl]-1,5-dimethyl-1,3-hexadien-1-yl]-7,11-dimethyloxacyclododec-9-en-2-one;Oxacyclododec-9-en-2-one, 8-(acetyloxy)-4,7-dihydroxy-12-[(1E,3E,5S)-6-[(2R,3R)-3-[(1R,2S)-2-hydroxy-1-methylbutyl]-2-oxiranyl]-1,5-dimethyl-1,3-hexadien-1-yl]-7,11-dimethyl-, (4R,7R,8S,9E,11S,12S)-
CBNumber: CB42666916
Molecular Formula: C30H48O8
Formula Weight: 536.7
MOL File: 445493-23-2.mol

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11107B Property

Boiling point:: 673.8±55.0 °C(Predicted)
Density: 1.13±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
form: A clear film
pka: 13.98±0.70(Predicted)
color: Colorless to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 16538
Product name: Pladienolide B
Purity: ≥95%
Packaging: 100μg
Price: $97
Updated: 2024/03/01

Cayman Chemical

Product number: 16538
Product name: Pladienolide B
Purity: ≥95%
Packaging: 500μg
Price: $410
Updated: 2024/03/01

Tocris

Product number: 6070
Product name: PladienolideB
Purity: ≥95%(HPLC)
Packaging: 500U
Price: $371
Updated: 2021/12/16

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11107B Chemical Properties,Usage,Production

Uses

Pladienolide B is the major analogue of a family of macrocyclic lactones isolated from Streptomyces platensis. Pladienolide B is a highly potent inhibitor of both hypoxia signals and cancer cell proliferation. Pladienolide B binds to SF3b complex blocking the spliceosome.

Uses

Pladienolide B is a potent cancer cell growth inhibitor that targets the SF3B1 subunit of the spliceosome.

storage

Store at -20°C

11107B Preparation Products And Raw materials

Raw materials

Preparation Products

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11107B Suppliers

China 22 United Kingdom 2 United States 3 USA 1 Global 28

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445493-23-2, 11107BRelated Search:

11107AD

11107B

PLADIENOLIDE B

SDOUORKJIJYJNW-VGQSKDSZSA-N

(4R,7R,8S,9E,11S,12S)-8-(Acetyloxy)-4,7-dihydroxy-12-[(1E,3E,5S)-6-[(2R,3R)-3-[(1R,2S)-2-hydroxy-1-methylbutyl]-2-oxiranyl]-1,5-dimethyl-1,3-hexadien-1-yl]-7,11-dimethyloxacyclododec-9-en-2-one

Oxacyclododec-9-en-2-one, 8-(acetyloxy)-4,7-dihydroxy-12-[(1E,3E,5S)-6-[(2R,3R)-3-[(1R,2S)-2-hydroxy-1-methylbutyl]-2-oxiranyl]-1,5-dimethyl-1,3-hexadien-1-yl]-7,11-dimethyl-, (4R,7R,8S,9E,11S,12S)-

445493-23-2