ChemicalBook > CAS DataBase List > 11107B
11107B
- Product Name
- 11107B
- CAS No.
- 445493-23-2
- Chemical Name
- 11107B
- Synonyms
- 11107B;11107AD;PLADIENOLIDE B;SDOUORKJIJYJNW-VGQSKDSZSA-N;(4R,7R,8S,9E,11S,12S)-8-(Acetyloxy)-4,7-dihydroxy-12-[(1E,3E,5S)-6-[(2R,3R)-3-[(1R,2S)-2-hydroxy-1-methylbutyl]-2-oxiranyl]-1,5-dimethyl-1,3-hexadien-1-yl]-7,11-dimethyloxacyclododec-9-en-2-one;Oxacyclododec-9-en-2-one, 8-(acetyloxy)-4,7-dihydroxy-12-[(1E,3E,5S)-6-[(2R,3R)-3-[(1R,2S)-2-hydroxy-1-methylbutyl]-2-oxiranyl]-1,5-dimethyl-1,3-hexadien-1-yl]-7,11-dimethyl-, (4R,7R,8S,9E,11S,12S)-
- CBNumber
- CB42666916
- Molecular Formula
- C30H48O8
- Formula Weight
- 536.7
- MOL File
- 445493-23-2.mol
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11107B Property
- Boiling point:
- 673.8±55.0 °C(Predicted)
- Density
- 1.13±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
- form
- A clear film
- pka
- 13.98±0.70(Predicted)
- color
- Colorless to off-white
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N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 16538
- Product name
- Pladienolide B
- Purity
- ≥95%
- Packaging
- 100μg
- Price
- $97
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 16538
- Product name
- Pladienolide B
- Purity
- ≥95%
- Packaging
- 500μg
- Price
- $410
- Updated
- 2024/03/01
Tocris
- Product number
- 6070
- Product name
- PladienolideB
- Purity
- ≥95%(HPLC)
- Packaging
- 500U
- Price
- $371
- Updated
- 2021/12/16
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11107B Chemical Properties,Usage,Production
Uses
Pladienolide B is the major analogue of a family of macrocyclic lactones isolated from Streptomyces platensis. Pladienolide B is a highly potent inhibitor of both hypoxia signals and cancer cell proliferation. Pladienolide B binds to SF3b complex blocking the spliceosome.
Uses
Pladienolide B is a potent cancer cell growth inhibitor that targets the SF3B1 subunit of the spliceosome.
storage
Store at -20°C
11107B Preparation Products And Raw materials
Raw materials
Preparation Products
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