ChemicalBook > CAS DataBase List > GLPG 0492

GLPG 0492

Product Name
GLPG 0492
CAS No.
1215085-92-9
Chemical Name
GLPG 0492
Synonyms
GLPG 0492;GLPG-0492 (GLPG0492);4-[(4S)-4-(Hydroxymethyl)-3-methyl-2,5-dioxo-4-phenyl-1-imidazolidinyl]-2-(trifluoromethyl)benzonitrile;Benzonitrile, 4-[(4S)-4-(hydroxymethyl)-3-methyl-2,5-dioxo-4-phenyl-1-imidazolidinyl]-2-(trifluoromethyl)-
CBNumber
CB42667074
Molecular Formula
C19H14F3N3O3
Formula Weight
389.33
MOL File
1215085-92-9.mol
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GLPG 0492 Property

Melting point:
66 - 71°C
Boiling point:
544.0±60.0 °C(Predicted)
Density 
1.50±0.1 g/cm3(Predicted)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
DMSO (Slightly), Ethanol (Slightly, Sonicated)
pka
13.50±0.10(Predicted)
form 
Solid
color 
White to Off-White
Stability:
Hygroscopic
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
29938
Product name
GLPG0492
Packaging
1mg
Price
$384
Updated
2024/03/01
TRC
Product number
G411000
Product name
GLPG-0492
Packaging
2.5mg
Price
$425
Updated
2021/12/16
TRC
Product number
G411000
Product name
GLPG-0492
Packaging
25mg
Price
$2360
Updated
2021/12/16
AK Scientific
Product number
3883DP
Product name
4-[(4S)-4-(Hydroxymethyl)-3-methyl-2,5-dioxo-4-phenylimidazolidin-1-yl]-2-(trifluoromethyl)benzonitrile
Packaging
1mg
Price
$525
Updated
2021/12/16
Crysdot
Product number
CD31004258
Product name
GLPG0492
Purity
98+%
Packaging
5mg
Price
$243
Updated
2021/12/16
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GLPG 0492 Chemical Properties,Usage,Production

Description

GLPG0492 is a selective androgen receptor modulator (SARM). It activates the androgen receptor in a transactivation assay (EC50 = 12 nM in HeLa cells expressing the human receptor). GLPG0492 (10 mg/kg per day) increases levator ani muscle weight, a marker of anabolic activity, but has no effect on ventral prostate weight, a marker of androgenic activity, in castrated rats. It increases twitch tension in isolated diaphragm strips, as well as increases the total distance run in a treadmill test and decreases gastrocnemius muscle fibrosis in the exercised-mdx mouse model of muscular dystrophy when administered at a dose of 30 mg/kg. GLPG0492 also reverses immobilization-induced muscle atrophy in a mouse model of hindlimb immobilization.

Uses

GLPG-0492 is a non-steroidal Selective Androgen Receptor Modulator (SARM), which can be used to reduce muscle loss while sparing reproductive tissues.

GLPG 0492 Preparation Products And Raw materials

Raw materials

Preparation Products

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GLPG 0492 Suppliers

China 35 India 2 United States 9 Global 46
Yichang Chanod Biomedical Technology Co,LTD
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0717-6855399 15377615856
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sales@sndswyy.cn
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China
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Haoyuan Chemexpress Co., Ltd.
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021-58950125
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(86) 21-58955996
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info@chemexpress.com
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China
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ShangHai Caerulum Pharma Discovery Co., Ltd.
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18149758185 18149758185
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sales-cpd@caerulumpharma.com
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China
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LETOPHARM LIMITED
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+86-21-5821 5861
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+86-21-5106 2861
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sales@letopharm.com
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China
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Birdo (Shanghai) Medical Technology Co., Ltd.
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021-58099077
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sales@birdochem.com
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Shanghai EFE Biological Technology Co., Ltd.
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021-65675885 18964387627
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Guangzhou QiYun Biotechnology Co., Ltd.
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ShangHai Biochempartner Co.,Ltd
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177-54423994 17754423994
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Amadis Chemical Company Limited
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HANGZHOU CLAP TECHNOLOGY CO.,LTD
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Hefei fuya biotechnology co. LTD
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ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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Absin Bioscience Inc.
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021-38015121 15000105423
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SHANGHAI T&W PHARMACEUTICAL CO., LTD.
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Energy Chemical
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Shanghai Dexuan Pharmaceutical Technology Co., Ltd
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JinOu Biomedical (Nanjing) Co., Ltd.
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jinoupharma@163.com
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China
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Changzhou Bojia Biomedical Technology Co., Ltd.
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czbjpharma@126.com
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TargetMol Chemicals Inc.
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https://hanhongsci.com/
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China
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Shandong Mopai Biotechnology Co., Ltd
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Nanjing Shizhou Biology Technology Co.,Ltd
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Olix (Shanghai) Pharmaceutical Technology Co., Ltd
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Shaanxi Cuikang Pharmaceutical Technology Co., Ltd
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Nantong Guangyuan Chemicl Co,Ltd
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+undefined17712220823
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Hebei Xinsheng New Material Technology Co., LTD.
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Anhui Ruihan Technology Co., Ltd
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Zibo Hangyu Biotechnology Development Co., Ltd
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Hebei Shengyuan Jinlong Import and Export Co. LTD
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Wuhan senwayer century chemical Co.,Ltd
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Shanghai Hao Zhun Biological Technology Co., Ltd.
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View Lastest Price from GLPG 0492 manufacturers

Wuhan Senwayer Century Chemical Co.,Ltd
Product
GLPG-0492 1215085-92-9
Price
US $0.00/gram
Min. Order
10gram
Purity
99% min
Supply Ability
20 tons
Release date
2022-10-20
Nantong Guangyuan Chemicl Co,Ltd
Product
GLPG0492 1215085-92-9
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000kg
Release date
2023-11-30
Hebei Xinsheng New Material Technology Co., LTD.
Product
GLPG 0492 1215085-92-9
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99.9%
Supply Ability
20tons
Release date
2023-09-01

1215085-92-9, GLPG 0492Related Search:


  • GLPG 0492
  • GLPG-0492 (GLPG0492)
  • Benzonitrile, 4-[(4S)-4-(hydroxymethyl)-3-methyl-2,5-dioxo-4-phenyl-1-imidazolidinyl]-2-(trifluoromethyl)-
  • 4-[(4S)-4-(Hydroxymethyl)-3-methyl-2,5-dioxo-4-phenyl-1-imidazolidinyl]-2-(trifluoromethyl)benzonitrile
  • 1215085-92-9