GLPG 0492
- Product Name
- GLPG 0492
- CAS No.
- 1215085-92-9
- Chemical Name
- GLPG 0492
- Synonyms
- GLPG 0492;GLPG-0492 (GLPG0492);4-[(4S)-4-(Hydroxymethyl)-3-methyl-2,5-dioxo-4-phenyl-1-imidazolidinyl]-2-(trifluoromethyl)benzonitrile;Benzonitrile, 4-[(4S)-4-(hydroxymethyl)-3-methyl-2,5-dioxo-4-phenyl-1-imidazolidinyl]-2-(trifluoromethyl)-
- CBNumber
- CB42667074
- Molecular Formula
- C19H14F3N3O3
- Formula Weight
- 389.33
- MOL File
- 1215085-92-9.mol
GLPG 0492 Property
- Melting point:
- 66 - 71°C
- Boiling point:
- 544.0±60.0 °C(Predicted)
- Density
- 1.50±0.1 g/cm3(Predicted)
- storage temp.
- Hygroscopic, -20°C Freezer, Under inert atmosphere
- solubility
- DMSO (Slightly), Ethanol (Slightly, Sonicated)
- pka
- 13.50±0.10(Predicted)
- form
- Solid
- color
- White to Off-White
- Stability:
- Hygroscopic
N-Bromosuccinimide Price
- Product number
- 29938
- Product name
- GLPG0492
- Packaging
- 1mg
- Price
- $384
- Updated
- 2024/03/01
- Product number
- G411000
- Product name
- GLPG-0492
- Packaging
- 2.5mg
- Price
- $425
- Updated
- 2021/12/16
- Product number
- G411000
- Product name
- GLPG-0492
- Packaging
- 25mg
- Price
- $2360
- Updated
- 2021/12/16
- Product number
- 3883DP
- Product name
- 4-[(4S)-4-(Hydroxymethyl)-3-methyl-2,5-dioxo-4-phenylimidazolidin-1-yl]-2-(trifluoromethyl)benzonitrile
- Packaging
- 1mg
- Price
- $525
- Updated
- 2021/12/16
- Product number
- CD31004258
- Product name
- GLPG0492
- Purity
- 98+%
- Packaging
- 5mg
- Price
- $243
- Updated
- 2021/12/16
GLPG 0492 Chemical Properties,Usage,Production
Description
GLPG0492 is a selective androgen receptor modulator (SARM). It activates the androgen receptor in a transactivation assay (EC50 = 12 nM in HeLa cells expressing the human receptor). GLPG0492 (10 mg/kg per day) increases levator ani muscle weight, a marker of anabolic activity, but has no effect on ventral prostate weight, a marker of androgenic activity, in castrated rats. It increases twitch tension in isolated diaphragm strips, as well as increases the total distance run in a treadmill test and decreases gastrocnemius muscle fibrosis in the exercised-mdx mouse model of muscular dystrophy when administered at a dose of 30 mg/kg. GLPG0492 also reverses immobilization-induced muscle atrophy in a mouse model of hindlimb immobilization.
Uses
GLPG-0492 is a non-steroidal Selective Androgen Receptor Modulator (SARM), which can be used to reduce muscle loss while sparing reproductive tissues.
GLPG 0492 Preparation Products And Raw materials
Raw materials
Preparation Products
GLPG 0492 Suppliers
- Tel
- --
- Fax
- --
- mktg@pharmaffiliates.com
- Country
- India
- ProdList
- 6739
- Advantage
- 58
View Lastest Price from GLPG 0492 manufacturers
- Product
- GLPG-0492 1215085-92-9
- Price
- US $0.00/gram
- Min. Order
- 10gram
- Purity
- 99% min
- Supply Ability
- 20 tons
- Release date
- 2022-10-20
- Product
- GLPG0492 1215085-92-9
- Price
- US $10.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 1000kg
- Release date
- 2023-11-30
- Product
- GLPG 0492 1215085-92-9
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 99.9%
- Supply Ability
- 20tons
- Release date
- 2023-09-01