ChemicalBook > CAS DataBase List > soyosaponin Ab

soyosaponin Ab

Product Name: soyosaponin Ab
CAS No.: 118194-13-1
Chemical Name: soyosaponin Ab
Synonyms: soyosaponin Ab;Soyasaponin Ab;Acetylsoyasaponin A1;inhibit,Soyasaponin Ab,Inhibitor;Soyasaponin Ab Acetylsoyasaponin A1;β-D-Glucopyranosiduronic acid, (3β,4β,21β,22β)-21,23-dihydroxy-22-[[3-O-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-α-L-arabinopyranosyl]oxy]olean-12-en-3-yl O-β-D-glucopyranosyl-(1→2)-O-β-D-galactopyranosyl-(1→2)-
CBNumber: CB42672946
Molecular Formula: C67H104O33
Formula Weight: 1437.52
MOL File: 118194-13-1.mol

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soyosaponin Ab Property

Melting point:: 253-256℃
Density: 1.49±0.1 g/cm3(Predicted)
pka: 2.76±0.70(Predicted)
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: S677810
Product name: SoyasaponinAb
Packaging: 5mg
Price: $485
Updated: 2021/12/16

Usbiological

Product number: 301003
Product name: Soyasaponin Ab
Packaging: 10mg
Price: $581
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb259511
Product name: Soyasaponin Ab
Purity: 98%
Packaging: 20mg
Price: $567.8
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb259511
Product name: Soyasaponin Ab
Purity: 98%
Packaging: 10mg
Price: $408
Updated: 2021/12/16

ChemScene

Product number: CS-0023029
Product name: SoyasaponinAb
Packaging: 5mg
Price: $202
Updated: 2021/12/16

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soyosaponin Ab Chemical Properties,Usage,Production

Uses

Soyosaponin Ab is a cytotoxic agent and acts as an immunomodulatory agent.

in vivo

Soyasaponin Ab (10-20 mg/kg; p.o.; daily for 5 days) shows inhibitory effect in 2,4,6-trinitrobenzene sulfonic acid (TNBS)-induced colitis in male ICR mice^[3].
Soyasaponin Ab (5-40 mg/kg; p.o.; one hour before the trial) significantly prevents Scopolamine (HY-N0296)-induced memory impairment in male ICR mice^[4].

Animal Model:	Male ICR mice (18-22 g, 5 weeks)^[4]
Dosage:	5, 10, 20, 40 mg/kg
Administration:	Oral gavage (p.o.); One hour before the trial, and memory impairment was induced by intraperitoneal injection of Scopolamine (0.9 mg/kg) 30 min after oral administrations of test agents.
Result:	Restored memory impairment to 86% at a dose of 10 mg/kg of untreated normal control mice in the passive avoidance task. Restored spontaneous alteration, which was lowered by Scopolamine on the Y-maze task. Significantly shortened the escape latencies on the fifth day.

Animal Model:	Male institute of cancer research (ICR) mice (20-22 g, 4 weeks)^[3]
Dosage:	10, 20 mg/kg
Administration:	Oral gavage (p.o.); daily for 5 days
Result:	Inhibited TNBS-induced body weight reduction, colon shortening, macroscopic score, and myeloperoxidase activity. Inhibited the expression of pro-inflammatory cytokines (TNF-α, IL-1β, IL-6). Ameliorated changes of TNBS-treated mouse colons which showed increased neutrophils, massive bowel edema, dense infiltration of the superficial layers of the mucosa, and epithelial cell disruption by large ulcerations. Inhibited the expression of TLR4, COX-2, and iNOS and the phosphorylation of IRAK1, IKK-β and p65, although it reversed IRAK-1 expression.

soyosaponin Ab Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from soyosaponin Ab manufacturers

Shanghai Standard Technology Co., Ltd.

Product: Soyosaponin Ab 118194-13-1
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2020-03-06

118194-13-1, soyosaponin AbRelated Search:

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soyosaponin Ab

Acetylsoyasaponin A1

Soyasaponin Ab

Soyasaponin Ab Acetylsoyasaponin A1

β-D-Glucopyranosiduronic acid, (3β,4β,21β,22β)-21,23-dihydroxy-22-[[3-O-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-α-L-arabinopyranosyl]oxy]olean-12-en-3-yl O-β-D-glucopyranosyl-(1→2)-O-β-D-galactopyranosyl-(1→2)-

inhibit,Soyasaponin Ab,Inhibitor

118194-13-1

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract