SOYASAPONIN I

Product Name: SOYASAPONIN I
CAS No.: 51330-27-9
Chemical Name: SOYASAPONIN I
Synonyms: SCM 3B;SOYASAPONIN I;Soyasaponin Bb-RM;Soybean saponin BB;Soyasaponin I, 98%min;SOYASAPONIN I USP/EP/BP;SoyasaponinⅠ(Soyasaponin Bb);SOYASAPONIN BB; SOYASAPONIN I;Soyasaponin I (Soyasaponin Bb);2)-O-b-D-galactopyranosyl-(1®
CBNumber: CB5345670
Molecular Formula: C48H78O18
Formula Weight: 943.13
MOL File: 51330-27-9.mol

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SOYASAPONIN I Property

Melting point:: 220-222 °C(Solv: methanol (67-56-1))
Boiling point:: 1024.2±65.0 °C(Predicted)
Density: 1.41
storage temp.: 2-8°C
solubility: ethanol: soluble1mg/mL, clear, colorless
pka: 2.76±0.70(Predicted)
form: powder
color: White
biological source: Glycine max (soybean)
Stability:: Hygroscopic
InChIKey: PTDAHAWQAGSZDD-IOVCITQVSA-N

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Safety

WGK Germany: 3
HS Code: 29389090

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: S9951
Product name: Soyasaponin I
Packaging: 5mg
Price: $378
Updated: 2025/07/31

Sigma-Aldrich

Product number: S9951
Product name: Soyasaponin I
Packaging: 25mg
Price: $1510
Updated: 2025/07/31

TCI Chemical

Product number: O0587
Product name: Soyasaponin I
Packaging: 10MG
Price: $318
Updated: 2025/07/31

Cayman Chemical

Product number: 25140
Product name: Soyasaponin Bb
Purity: ≥95%
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 25140
Product name: Soyasaponin Bb
Purity: ≥95%
Packaging: 5mg
Price: $139
Updated: 2024/03/01

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SOYASAPONIN I Chemical Properties,Usage,Production

Description

Soyasaponin Bb is a triterpenoid saponin that has been found in soy and has enzyme inhibitory, antimetastatic, anti-inflammatory, and neuroprotective biological activities. It selectively inhibits human recombinant and porcine kidney renin (IC₅₀s = 30 and 30 μg/ml, respectively) over bovine trypsin, human urinary kallikrein, and rabbit angiotensin converting enzyme (ACE) when used at a concentration of 100 μg/ml. Soyasaponin Bb inhibits the mouse brain sialyltransferase ST3GAL1 (K_i = 2.1 μM) and decreases levels of α2,3-linked sialic acid on the cell surface and decreases migration of B16/F10 mouse melanoma cells in vitro when used at a concentration of 75 μM. It also dose-dependently increases viability and mRNA expression of heme oxygenase-1 (HO-1) in BRL 3A immortalized rat hepatocytes subjected to alcohol-induced oxidative stress. Soyasaponin Bb (10 mg/kg per day) increases the latency to enter the dark chamber in a passive avoidance test and the percentage of spontaneous alterations in the Y-maze test in a rat model of learning and memory impairment induced by ibotenic acid .

Uses

Soyasaponin I has been used:

to test its effect on migration and invasion of ovarian cancer cell lines
as standard for the quantification of saponins from quinoa and fenugreek samples
as L-15 medium supplement for Zebrafish liver cell lines

Definition

ChEBI: Soyasaponin I is a triterpenoid saponin that is composed of soyasapogenol B having an alpha-L-rhamnopyranosyl-(1->2)-beta-D-galactopyranosyl-(1->2)-beta-D-glucopyranosiduronic acid moiety attached at the 3-position via a glycosidic linkage. It has a role as a sialyltransferase inhibitor. It is a pentacyclic triterpenoid, a triterpenoid saponin, a trisaccharide derivative and a carbohydrate acid derivative. It is functionally related to a soyasapogenol B. It is a conjugate acid of a soyasaponin I(1-).

General Description

Soyasaponin I is an oleanene-type triterpenoid aglycone and is a group B soyasaponin. It is an amphiphilic molecule and is metabolized by intestinal bacteria into sugars and aglycones.

Biochem/physiol Actions

Antioxidant and anti-inflammatory saponin found in soybean. Attenuates TNBS-induced colitis in mice. The structure consists of a glycoside moiety and triterpene derivative. Sialytransferase inhibitor and renin inhibitor.

References

[1] WEI ZHANG D G P. Chemical and biological characterization of oleanane triterpenoids from soy.[J]. Molecules, 2009, 14 8: 2959-2975. DOI: 10.3390/molecules14082959
[2] SAORI TAKAHASHI. Isolation of human renin inhibitor from soybean: soyasaponin I is the novel human renin inhibitor in soybean.[J]. Bioscience, Biotechnology, and Biochemistry, 2008, 72 12: 3232-3236. DOI: 10.1271/bbb.80495
[3] CHI-YUE WU . Soyasaponin I, a Potent and Specific Sialyltransferase Inhibitor[J]. Biochemical and biophysical research communications, 2001, 284 2: Pages 466-469. DOI: 10.1006/bbrc.2001.5002
[4] WEI-WEI CHANG . Soyasaponin I decreases the expression of α2,3-linked sialic acid on the cell surface and suppresses the metastatic potential of B16F10 melanoma cells[J]. Biochemical and biophysical research communications, 2006, 341 2: Pages 614-619. DOI: 10.1016/j.bbrc.2005.12.216
[5] ZHU LIJIE. Soyasaponin Bb Protects Rat Hepatocytes from Alcohol-Induced Oxidative Stress by Inducing Heme Oxygenase-1[J]. Pharmacognosy Magazine, 2016, 46 1: 302-306. DOI: 10.4103/0973-1296.192203
[6] SUNG-WOON HONG. Soyasaponin I improved neuroprotection and regeneration in memory deficient model rats.[J]. PLoS ONE, 2013: e81556. DOI: 10.1371/journal.pone.0081556

SOYASAPONIN I Preparation Products And Raw materials

Raw materials

Preparation Products

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SOYASAPONIN I Suppliers

China 177 Germany 1 Japan 1 United Kingdom 3 United States 16 USA 1 Global 199

Shanghai Tauto Biotech Co., Ltd.

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View Lastest Price from SOYASAPONIN I manufacturers

Changsha Staherb Natural Ingredients Co., Ltd.

Product: SOYASAPONIN I； Soybean Extract 51330-27-9
Price: US $0.00/KG
Min. Order: 1KG
Purity: ≥98% HPLC
Supply Ability: 1000KG
Release date: 2022-09-16

Hebei Chuanghai Biotechnology Co., Ltd

Product: Soyasaponin I 51330-27-9
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-10-28

Shanghai Standard Technology Co., Ltd.

Product: Soyasaponin Bb 51330-27-9
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2020-03-06

51330-27-9, SOYASAPONIN IRelated Search:

Daidzein 6''-O-ACETYLGLYCITIN Daidzin Genistin Glycitin Soyosaponin Ac soyosaponin Ab Soyasaponin Ba SOYASAPOGENOL A(P) Soyasaponin Aa SOYASAPOGENOL B(P) SOYASAPONIN I 1,1-Dimethoxy-2-(2-methoxyethoxy)ethane 2-[2-(2-METHOXYETHOXY)ETHOXY]ACETIC ACID C18E3 SOYASAPONIN III SOYASAPONIN IV (2S,3S,4S,5R,6R)-6-[[(3S,4S,4aR,6aR,6bS,8aR,9S,12aR,14aS,14bR)-9-hydro xy-4-(hydroxymethyl)-4,6a,6b,8a,11,11,14b-heptamethyl-1,2,3,4a,5,6,7,8 ,9,10,12,12a,14,14a-tetradecahydropicen-3-yl]oxy]-5-[(2S,3R,4S,5S)-4,5 -dihydroxy-3-[(2S,3R,4R,5S,6S)-3,4,5-trihydroxy-6-methyl-oxan-2-yl]oxy -oxan-2-yl]oxy-3,4-dihydroxy-oxane-2-carboxylic acid

SOYASAPONIN I

β-D-Glucopyranosiduronic acid, (3β,4β,22β)-22,23-dihydroxyolean-12-en-3-yl O-6-deoxy-α-L-Mannopyranosyl-(1→2)-O-β-D-galactopyranosyl-(1→2)-

2)-O-b-D-galactopyranosyl-(1&reg

b-D-Glucopyranosiduronic acid, (3b,4b,22b)-22,23-dihydroxyolean-12-en-3-yl O-6-deoxy-a-L-Mannopyranosyl-(1&reg

SoyasaponinⅠ(Soyasaponin Bb)

SCM 3B

SOYASAPONIN BB; SOYASAPONIN I

SOYASAPONIN I USP/EP/BP

(3beta,22beta)-22,24-dihydroxyolean-12-en-3-yl 6-deoxy-alpha...

Inhibitor,inhibit,Soyasaponin Bb

(2S,3S,4S,5R,6R)-5-(((2S,3R,4S,5R,6R)-4,5-Dihydroxy-6-(hydroxymethyl)-3-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-3,4-dihydroxy-6-(((3S,4S,4aR,6aR,6bS,8aR,9R,12aS,14aR,14bR)-9-hydroxy-4-(hydroxymethyl)-4,6a,6b,8a,11,11,14b-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicen-3-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid

Soybean saponin BB

Soyasaponin I (Soyasaponin Bb)

Soyasaponin Bb-RM

Soyasaponin I, 98%min

51330-27-9

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract

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