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SOYASAPONIN I

Product Name
SOYASAPONIN I
CAS No.
51330-27-9
Chemical Name
SOYASAPONIN I
Synonyms
SCM 3B;SOYASAPONIN I;Soybean saponin BB;SOYASAPONIN I USP/EP/BP;SoyasaponinⅠ(Soyasaponin Bb);SOYASAPONIN BB; SOYASAPONIN I;Soyasaponin I (Soyasaponin Bb);2)-O-b-D-galactopyranosyl-(1®Inhibitor,inhibit,Soyasaponin Bb;(3beta,22beta)-22,24-dihydroxyolean-12-en-3-yl 6-deoxy-alpha...
CBNumber
CB5345670
Molecular Formula
C48H78O18
Formula Weight
943.13
MOL File
51330-27-9.mol
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SOYASAPONIN I Property

Melting point:
220-222 °C(Solv: methanol (67-56-1))
Boiling point:
1024.2±65.0 °C(Predicted)
Density 
1.41
storage temp. 
2-8°C
solubility 
ethanol: soluble1mg/mL, clear, colorless
pka
2.76±0.70(Predicted)
form 
powder
color 
White
Stability:
Hygroscopic
InChIKey
PTDAHAWQAGSZDD-IOVCITQVSA-N
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Safety

WGK Germany 
3
HS Code 
29389090
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S9951
Product name
Soyasaponin I
Packaging
5mg
Price
$368
Updated
2024/03/01
Sigma-Aldrich
Product number
S9951
Product name
Soyasaponin I
Packaging
25mg
Price
$1470
Updated
2024/03/01
Cayman Chemical
Product number
25140
Product name
Soyasaponin Bb
Purity
≥95%
Packaging
1mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
25140
Product name
Soyasaponin Bb
Purity
≥95%
Packaging
5mg
Price
$139
Updated
2024/03/01
Sigma-Aldrich
Product number
PHL83545
Product name
Soyasaponin Bb
Purity
phyproof? Reference Substance
Packaging
10mg
Price
$514
Updated
2024/03/01
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SOYASAPONIN I Chemical Properties,Usage,Production

Description

Soyasaponin Bb is a triterpenoid saponin that has been found in soy and has enzyme inhibitory, antimetastatic, anti-inflammatory, and neuroprotective biological activities. It selectively inhibits human recombinant and porcine kidney renin (IC50s = 30 and 30 μg/ml, respectively) over bovine trypsin, human urinary kallikrein, and rabbit angiotensin converting enzyme (ACE) when used at a concentration of 100 μg/ml. Soyasaponin Bb inhibits the mouse brain sialyltransferase ST3GAL1 (Ki = 2.1 μM) and decreases levels of α2,3-linked sialic acid on the cell surface and decreases migration of B16/F10 mouse melanoma cells in vitro when used at a concentration of 75 μM. It also dose-dependently increases viability and mRNA expression of heme oxygenase-1 (HO-1) in BRL 3A immortalized rat hepatocytes subjected to alcohol-induced oxidative stress. Soyasaponin Bb (10 mg/kg per day) increases the latency to enter the dark chamber in a passive avoidance test and the percentage of spontaneous alterations in the Y-maze test in a rat model of learning and memory impairment induced by ibotenic acid .

Uses

Soyasaponin I has been used:

  • to test its effect on migration and invasion of ovarian cancer cell lines
  • as standard for the quantification of saponins from quinoa and fenugreek samples
  • as L-15 medium supplement for Zebrafish liver cell lines

Definition

ChEBI: Soyasaponin I is a triterpenoid saponin that is composed of soyasapogenol B having an alpha-L-rhamnopyranosyl-(1->2)-beta-D-galactopyranosyl-(1->2)-beta-D-glucopyranosiduronic acid moiety attached at the 3-position via a glycosidic linkage. It has a role as a sialyltransferase inhibitor. It is a pentacyclic triterpenoid, a triterpenoid saponin, a trisaccharide derivative and a carbohydrate acid derivative. It is functionally related to a soyasapogenol B. It is a conjugate acid of a soyasaponin I(1-).

General Description

Soyasaponin I is an oleanene-type triterpenoid aglycone and is a group B soyasaponin. It is an amphiphilic molecule and is metabolized by intestinal bacteria into sugars and aglycones.

Biochem/physiol Actions

Antioxidant and anti-inflammatory saponin found in soybean. Attenuates TNBS-induced colitis in mice. The structure consists of a glycoside moiety and triterpene derivative. Sialytransferase inhibitor and renin inhibitor.

SOYASAPONIN I Preparation Products And Raw materials

Raw materials

Preparation Products

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SOYASAPONIN I Suppliers

Shanghai Tauto Biotech Co., Ltd.
Tel
021-51320588
Fax
0086-21-51320502
Email
tauto@tautobiotech.com
Country
China
ProdList
3989
Advantage
66
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
27322
Advantage
60
Chembest Research Laboratories Limited
Tel
021-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6009
Advantage
61
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18739
Advantage
57
Chengdu Biopurify Phytochemicals Ltd.
Tel
+86-028-82633397 18982077548
Fax
+86-28-82633165
Email
cwb1@biopurify.cn
Country
China
ProdList
2376
Advantage
60
Chengdu Climax Biotech Co., Ltd.
Tel
028-83311324 1278112614
Fax
028-83311324
Email
climaxbiotech@gmail.com
Country
China
ProdList
925
Advantage
58
Shanghai Winherb Medical Technology Co., Ltd.
Tel
400-186-5138 13341702378
Fax
QQ:190129269
Email
winherb@126.com
Country
China
ProdList
1009
Advantage
58
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12338
Advantage
58
Shanghai Ruji Biology Technology Co., Ltd.
Tel
+86-21-65211385-8001 36031160
Fax
+86-21-65211385-8004
Email
sales@shruji.com
Country
China
ProdList
3224
Advantage
55
Shanghai BeiZhuo Biotech Co., Ltd.
Tel
021-61119791,13386096464
Fax
021-50190009
Email
bzswkf@foxmail.com
Country
China
ProdList
3924
Advantage
50
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View Lastest Price from SOYASAPONIN I manufacturers

Changsha Staherb Natural Ingredients Co., Ltd.
Product
SOYASAPONIN I; Soybean Extract 51330-27-9
Price
US $0.00/KG
Min. Order
1KG
Purity
≥98% HPLC
Supply Ability
1000KG
Release date
2022-09-16
Hebei Guanlang Biotechnology Co., Ltd.
Product
Soyasaponin I 51330-27-9
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2022-10-18
Shanghai Standard Technology Co., Ltd.
Product
Soyasaponin Bb 51330-27-9
Price
US $0.00/mg
Min. Order
5mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2020-03-06

51330-27-9, SOYASAPONIN IRelated Search:


  • SOYASAPONIN I
  • β-D-Glucopyranosiduronic acid, (3β,4β,22β)-22,23-dihydroxyolean-12-en-3-yl O-6-deoxy-α-L-Mannopyranosyl-(1→2)-O-β-D-galactopyranosyl-(1→2)-
  • 2)-O-b-D-galactopyranosyl-(1&reg
  • b-D-Glucopyranosiduronic acid, (3b,4b,22b)-22,23-dihydroxyolean-12-en-3-yl O-6-deoxy-a-L-Mannopyranosyl-(1&reg
  • SoyasaponinⅠ(Soyasaponin Bb)
  • SCM 3B
  • SOYASAPONIN BB; SOYASAPONIN I
  • SOYASAPONIN I USP/EP/BP
  • (3beta,22beta)-22,24-dihydroxyolean-12-en-3-yl 6-deoxy-alpha...
  • Inhibitor,inhibit,Soyasaponin Bb
  • (2S,3S,4S,5R,6R)-5-(((2S,3R,4S,5R,6R)-4,5-Dihydroxy-6-(hydroxymethyl)-3-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-3,4-dihydroxy-6-(((3S,4S,4aR,6aR,6bS,8aR,9R,12aS,14aR,14bR)-9-hydroxy-4-(hydroxymethyl)-4,6a,6b,8a,11,11,14b-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicen-3-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
  • Soybean saponin BB
  • Soyasaponin I (Soyasaponin Bb)
  • 51330-27-9
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
  • Miscellaneous Natural Products