SOYASAPONIN I
- Product Name
- SOYASAPONIN I
- CAS No.
- 51330-27-9
- Chemical Name
- SOYASAPONIN I
- Synonyms
- SCM 3B;SOYASAPONIN I;Soyasaponin Bb-RM;Soybean saponin BB;SOYASAPONIN I USP/EP/BP;SoyasaponinⅠ(Soyasaponin Bb);SOYASAPONIN BB; SOYASAPONIN I;Soyasaponin I (Soyasaponin Bb);2)-O-b-D-galactopyranosyl-(1®Inhibitor,inhibit,Soyasaponin Bb
- CBNumber
- CB5345670
- Molecular Formula
- C48H78O18
- Formula Weight
- 943.13
- MOL File
- 51330-27-9.mol
SOYASAPONIN I Property
- Melting point:
- 220-222 °C(Solv: methanol (67-56-1))
- Boiling point:
- 1024.2±65.0 °C(Predicted)
- Density
- 1.41
- storage temp.
- 2-8°C
- solubility
- ethanol: soluble1mg/mL, clear, colorless
- pka
- 2.76±0.70(Predicted)
- form
- powder
- color
- White
- Stability:
- Hygroscopic
- InChIKey
- PTDAHAWQAGSZDD-IOVCITQVSA-N
Safety
- WGK Germany
- 3
- HS Code
- 29389090
N-Bromosuccinimide Price
- Product number
- S9951
- Product name
- Soyasaponin I
- Packaging
- 5mg
- Price
- $368
- Updated
- 2024/03/01
- Product number
- S9951
- Product name
- Soyasaponin I
- Packaging
- 25mg
- Price
- $1470
- Updated
- 2024/03/01
- Product number
- 25140
- Product name
- Soyasaponin Bb
- Purity
- ≥95%
- Packaging
- 1mg
- Price
- $32
- Updated
- 2024/03/01
- Product number
- 25140
- Product name
- Soyasaponin Bb
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $139
- Updated
- 2024/03/01
- Product number
- PHL83545
- Product name
- Soyasaponin Bb
- Purity
- phyproof? Reference Substance
- Packaging
- 10mg
- Price
- $514
- Updated
- 2024/03/01
SOYASAPONIN I Chemical Properties,Usage,Production
Description
Soyasaponin Bb is a triterpenoid saponin that has been found in soy and has enzyme inhibitory, antimetastatic, anti-inflammatory, and neuroprotective biological activities. It selectively inhibits human recombinant and porcine kidney renin (IC50s = 30 and 30 μg/ml, respectively) over bovine trypsin, human urinary kallikrein, and rabbit angiotensin converting enzyme (ACE) when used at a concentration of 100 μg/ml. Soyasaponin Bb inhibits the mouse brain sialyltransferase ST3GAL1 (Ki = 2.1 μM) and decreases levels of α2,3-linked sialic acid on the cell surface and decreases migration of B16/F10 mouse melanoma cells in vitro when used at a concentration of 75 μM. It also dose-dependently increases viability and mRNA expression of heme oxygenase-1 (HO-1) in BRL 3A immortalized rat hepatocytes subjected to alcohol-induced oxidative stress. Soyasaponin Bb (10 mg/kg per day) increases the latency to enter the dark chamber in a passive avoidance test and the percentage of spontaneous alterations in the Y-maze test in a rat model of learning and memory impairment induced by ibotenic acid .
Uses
Soyasaponin I has been used:
- to test its effect on migration and invasion of ovarian cancer cell lines
- as standard for the quantification of saponins from quinoa and fenugreek samples
- as L-15 medium supplement for Zebrafish liver cell lines
Definition
ChEBI: Soyasaponin I is a triterpenoid saponin that is composed of soyasapogenol B having an alpha-L-rhamnopyranosyl-(1->2)-beta-D-galactopyranosyl-(1->2)-beta-D-glucopyranosiduronic acid moiety attached at the 3-position via a glycosidic linkage. It has a role as a sialyltransferase inhibitor. It is a pentacyclic triterpenoid, a triterpenoid saponin, a trisaccharide derivative and a carbohydrate acid derivative. It is functionally related to a soyasapogenol B. It is a conjugate acid of a soyasaponin I(1-).
General Description
Soyasaponin I is an oleanene-type triterpenoid aglycone and is a group B soyasaponin. It is an amphiphilic molecule and is metabolized by intestinal bacteria into sugars and aglycones.
Biochem/physiol Actions
Antioxidant and anti-inflammatory saponin found in soybean. Attenuates TNBS-induced colitis in mice. The structure consists of a glycoside moiety and triterpene derivative. Sialytransferase inhibitor and renin inhibitor.
SOYASAPONIN I Preparation Products And Raw materials
Raw materials
Preparation Products
SOYASAPONIN I Suppliers
- Tel
- --
- Fax
- --
- info-tech@nacalai.co.jp
- Country
- Japan
- ProdList
- 6046
- Advantage
- 75
View Lastest Price from SOYASAPONIN I manufacturers
- Product
- SOYASAPONIN I； Soybean Extract 51330-27-9
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- ≥98% HPLC
- Supply Ability
- 1000KG
- Release date
- 2022-09-16
- Product
- Soyasaponin I 51330-27-9
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2024-10-28
- Product
- Soyasaponin Bb 51330-27-9
- Price
- US $0.00/mg
- Min. Order
- 5mg
- Purity
- ≥98%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2020-03-06