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BroMocriptine-13C-d3

Product Name
BroMocriptine-13C-d3
Chemical Name
BroMocriptine-13C-d3
Synonyms
BroMocriptine-13C-d3
CBNumber
CB42673660
Molecular Formula
C32H37BrD3N5O5
Formula Weight
658.621985334
MOL File
Mol file
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BroMocriptine-13C-d3 Property

solubility 
Chloroform: soluble
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
26669
Product name
Bromocriptine-13C-d3
Packaging
500μg
Price
$413
Updated
2024/03/01
Cayman Chemical
Product number
26669
Product name
Bromocriptine-13C-d3
Packaging
1mg
Price
$783
Updated
2024/03/01
American Custom Chemicals Corporation
Product number
RDL0006691
Product name
BROMOCRIPTINE-13C-D3
Purity
95.00%
Packaging
5MG
Price
$500.93
Updated
2021/12/16
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BroMocriptine-13C-d3 Chemical Properties,Usage,Production

Description

Bromocriptine-13C-d3 is intended for use as an internal standard for the quantification of bromocriptine (Item No. 14598) by GC- or LC-MS. Bromocriptine is a dopamine receptor agonist (Kis = 1,659, 12.2, 12.2, 59.7, and 1,691 nM for dopamine D1, D2, D3, D4, and D5 receptors, respectively).1 It also binds to the serotonin (5-HT) receptor subtypes 5-HT1A and 5-HT1D (Kis = 12.9 and 10.7 nM, respectively), as well as α1-adrenergic receptors (Kis = 1.12-4.17 nM).1,2 Bromocriptine (5 mg/kg) restores locomotor activity, without inducing dyskinesia, in a macaque model of Parkinson’s disease induced by MPTP.3 Formulations containing bromocriptine have been used in the treatment of Parkinson's disease, hyperprolactinemia-associated dysfunctions, and acromegaly.WARNING This product is not for human or veterinary use.

References

[1] MSC TROND KVERNMO  PhD E B  PhD Sebastian Härtter. A review of the receptor-binding and pharmacokinetic properties of dopamine agonists[J]. Clinical therapeutics, 2006, 28 8: Pages 1065-1078. DOI: 10.1016/j.clinthera.2006.08.004
[2] MARK J MILLAN. Differential actions of antiparkinson agents at multiple classes of monoaminergic receptor. I. A multivariate analysis of the binding profiles of 14 drugs at 21 native and cloned human receptor subtypes.[J]. Journal of Pharmacology and Experimental Therapeutics, 2002, 303 2: 791-804. DOI: 10.1124/jpet.102.039867
[3] C. ROUILLARD  T. D P  P J Bédard. Effects of chronic treatment of MPTP monkeys with bromocriptine alone or in combination with SKF 38393[J]. European journal of pharmacology, 1990, 185 2: Pages 209-215. DOI: 10.1016/0014-2999(90)90642-j

BroMocriptine-13C-d3 Preparation Products And Raw materials

Raw materials

Preparation Products

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BroMocriptine-13C-d3 Suppliers

ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11218
Advantage
58
TLC Pharmaceutical Standards Ltd.
Tel
18012923235; 18012923235
Email
chinasales04@tlcstandards.com.cn
Country
China
ProdList
7974
Advantage
58
BePure (Beijing) Biotechnology Co.
Tel
58896805
Email
7993601name@qq.com
Country
CHINA
ProdList
6620
Advantage
58
Cayman Chemical Company
Tel
800-364-9897
Email
sales@caymanchem.com
Country
China
ProdList
6838
Advantage
58
TargetMol Chemicals Inc.
Tel
+17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
19962
Advantage
58